TC-1 is a novel tumorigenic and natively disordered protein associated with thyroid cancer
about
C8orf4 negatively regulates self-renewal of liver cancer stem cells via suppression of NOTCH2 signallingWnt/beta-catenin signaling and small molecule inhibitorsTC1(C8orf4) regulates hematopoietic stem/progenitor cells and hematopoiesisA decade and a half of protein intrinsic disorder: biology still waits for physicsStructural characterization of partially disordered human Chibby: insights into its function in the Wnt-signaling pathwayUnderstanding protein non-folding.Nuclear magnetic resonance and circular dichroism study of metastin (Kisspeptin-54) structure in solution.Potential utility and limitations of thyroid cancer cell lines as models for studying thyroid cancer.TC-1 overexpression promotes cell proliferation in human non-small cell lung cancer that can be inhibited by PD173074.A molecular computational model improves the preoperative diagnosis of thyroid nodules.Effects of molecular crowding on the dynamics of intrinsically disordered proteins.Tight regulation of unstructured proteins: from transcript synthesis to protein degradationA link between smooth muscle cell death and extracellular matrix degradation during vascular atrophyPhosphorylation of Krüppel-like factor 3 (KLF3/BKLF) and C-terminal binding protein 2 (CtBP2) by homeodomain-interacting protein kinase 2 (HIPK2) modulates KLF3 DNA binding and activityIntrinsic disorder and functional proteomics.The combination of four molecular markers improves thyroid cancer cytologic diagnosis and patient management.Aberrant Activation of Notch Signaling Inhibits PROX1 Activity to Enhance the Malignant Behavior of Thyroid Cancer CellsEpigenetic regulation of cyclooxygenase-2 by methylation of c8orf4 in pulmonary fibrosisKnockdown of TC-1 enhances radiosensitivity of non-small cell lung cancer via the Wnt/β-catenin pathwayAbeta aggregation and possible implications in Alzheimer's disease pathogenesisAdipose tissue hyperplasia with enhanced adipocyte-derived stem cell activity in Tc1(C8orf4)-deleted mice.Protein intrinsic disorder as a flexible armor and a weapon of HIV-1.TC1(C8orf4) is upregulated by IL-1beta/TNF-alpha and enhances proliferation of human follicular dendritic cells.miR-199a-3p displays tumor suppressor functions in papillary thyroid carcinoma.Chibby functions in Xenopus ciliary assembly, embryonic development, and the regulation of gene expression.Thyroid cancer 1 (C8orf4) shows high expression, no mutation and reduced methylation level in lung cancers, and its expression correlates with β-catenin and DNMT1 expression and poor prognosisOn the intrinsic disorder status of the major players in programmed cell death pathways.The intrinsically disordered TC-1 interacts with Chibby via regions with high helical propensity.Human Thyroid Cancer-1 (TC-1) is a vertebrate specific oncogenic protein that protects against copper and pro-apoptotic genes in yeast.TC-1 (C8orf4) expression is correlated with differentiation in ovarian carcinomas and might distinguish metastatic ovarian from metastatic colorectal carcinomas.More than just tails: intrinsic disorder in histone proteins.The high expression of TC1 (C8orf4) was correlated with the expression of β-catenin and cyclin D1 and the progression of squamous cell carcinomas of the tongue.
P2860
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P2860
TC-1 is a novel tumorigenic and natively disordered protein associated with thyroid cancer
description
2004 nî lūn-bûn
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2004 թուականի Ապրիլին հրատարակուած գիտական յօդուած
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2004 թվականի ապրիլին հրատարակված գիտական հոդված
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2004年の論文
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2004年論文
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2004年論文
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2004年論文
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2004年論文
@zh-mo
2004年論文
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2004年论文
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name
TC-1 is a novel tumorigenic an ...... associated with thyroid cancer
@ast
TC-1 is a novel tumorigenic an ...... associated with thyroid cancer
@en
TC-1 is a novel tumorigenic an ...... associated with thyroid cancer
@nl
type
label
TC-1 is a novel tumorigenic an ...... associated with thyroid cancer
@ast
TC-1 is a novel tumorigenic an ...... associated with thyroid cancer
@en
TC-1 is a novel tumorigenic an ...... associated with thyroid cancer
@nl
prefLabel
TC-1 is a novel tumorigenic an ...... associated with thyroid cancer
@ast
TC-1 is a novel tumorigenic an ...... associated with thyroid cancer
@en
TC-1 is a novel tumorigenic an ...... associated with thyroid cancer
@nl
P2093
P50
P3181
P1433
P1476
TC-1 is a novel tumorigenic an ...... associated with thyroid cancer
@en
P2093
Alison K Death
Elizabeth L Chua
P304
P3181
P356
10.1158/0008-5472.CAN-03-2093
P407
P577
2004-04-01T00:00:00Z