Crh and Oprm1 mediate anxiety-related behavior and social approach in a mouse model of MECP2 duplication syndrome - Wikidata - wikimedia - TriplyDB

Crh and Oprm1 mediate anxiety-related behavior and social approach in a mouse model of MECP2 duplication syndrome

Crh and Oprm1 mediate anxiety-related behavior and social approach in a mouse model of MECP2 duplication syndrome

http://www.wikidata.org/entity/Q28257072

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MECP2 disorders: from the clinic to mice and back The molecular basis of cognitive deficits in pervasive developmental disorders Role of mecp2 in experience-dependent epigenetic programming Behavioral and Neuroanatomical Phenotypes in Mouse Models of Autism Reversal of phenotypes in MECP2 duplication mice using genetic rescue or antisense oligonucleotides.Ataxin1L is a regulator of HSC function highlighting the utility of cross-tissue comparisons for gene discovery Influenza A induces dysfunctional immunity and death in MeCP2-overexpressing mice.Loss of MeCP2 in cholinergic neurons causes part of RTT-like phenotypes via α7 receptor in hippocampus Loss of MeCP2 in the rat models regression, impaired sociability and transcriptional deficits of Rett syndrome.Induced gamma oscillations differentiate familiar and novel voices in children with MECP2 duplication and Rett syndromes.Mild expression differences of MECP2 influencing aggressive social behavior.Female Mecp2(+/-) mice display robust behavioral deficits on two different genetic backgrounds providing a framework for pre-clinical studies.Disruption of DNA-methylation-dependent long gene repression in Rett syndrome.Functional alterations in the dorsal raphe nucleus following acute and chronic ethanol exposure.Altered neuronal network and rescue in a human MECP2 duplication model.Applying the ethoexperimental approach to neurodevelopmental syndrome research reveals exaggerated defensive behavior in Mecp2 mutant mice.NUDT21-spanning CNVs lead to neuropsychiatric disease and altered MeCP2 abundance via alternative polyadenylation Synaptic plasticity in mouse models of autism spectrum disorders.The behavioral phenotype in MECP2 duplication syndrome: a comparison with idiopathic autism.Epigenetic mechanisms in neurological disease An AT-hook domain in MeCP2 determines the clinical course of Rett syndrome and related disorders.Tagging methyl-CpG-binding domain proteins reveals different spatiotemporal expression and supports distinct functions.Neuronal morphology in MeCP2 mouse models is intrinsically variable and depends on age, cell type, and Mecp2 mutation.Effects of early-life exposure to THIP on phenotype development in a mouse model of Rett syndrome.Dendritic arborization and spine dynamics are abnormal in the mouse model of MECP2 duplication syndrome.Transcriptional regulation in pluripotent stem cells by methyl CpG-binding protein 2 (MeCP2).DNA methylation in the gene body influences MeCP2-mediated gene repression.Distinct Defects in Spine Formation or Pruning in Two Gene Duplication Mouse Models of Autism.Synaptic plasticity and signaling in Rett syndrome.Rett syndrome: a complex disorder with simple roots.μ opioid receptor, social behaviour and autism spectrum disorder: reward matters.Autism genetics - an overview.Association analysis between the A118G polymorphism in the OPRM1 gene and treatment response to venlafaxine XR in generalized anxiety disorder.MeCP2 plays an analgesic role in pain transmission through regulating CREB / miR-132 pathway.Overexpression of methyl-CpG binding protein 2 impairs T(H)1 responses.Loss and Gain of MeCP2 Cause Similar Hippocampal Circuit Dysfunction that Is Rescued by Deep Brain Stimulation in a Rett Syndrome Mouse Model Altered visual cortical processing in a mouse model of MECP2 duplication syndrome.Diurnal Salivary Cortisol and Regression Status in MECP2 Duplication Syndrome.MECP2 impairs neuronal structure by regulating KIBRA.MeCP2-mediated alterations of striatal features accompany psychomotor deficits in a mouse model of Rett syndrome.

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Crh and Oprm1 mediate anxiety-related behavior and social approach in a mouse model of MECP2 duplication syndrome

http://www.wikidata.org/entity/Q28257072

description

2012 nî lūn-bûn

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2012 թուականի Յունուարին հրատարակուած գիտական յօդուած

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2012年の論文

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Crh and Oprm1 mediate anxiety- ...... of MECP2 duplication syndrome

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Crh and Oprm1 mediate anxiety- ...... of MECP2 duplication syndrome

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Crh and Oprm1 mediate anxiety- ...... of MECP2 duplication syndrome

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Bryan E McGill

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Caleigh Mandel-Brehm

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Christopher M McGraw

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P2860

Copy-number variations associated with neuropsychiatric conditions

Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2

Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex

MeCP2, a key contributor to neurological disease, activates and represses transcription

Loss of MeCP2 in aminergic neurons causes cell-autonomous defects in neurotransmitter synthesis and specific behavioral abnormalities

Identification of MeCP2 mutations in a series of females with autistic disorder

A mouse Mecp2-null mutation causes neurological symptoms that mimic Rett syndrome

Mice deficient for delta- and mu-opioid receptors exhibit opposing alterations of emotional responses

Corticotropin releasing factor receptor 1-deficient mice display decreased anxiety, impaired stress response, and aberrant neuroendocrine development

A partial loss of function allele of methyl-CpG-binding protein 2 predicts a human neurodevelopmental syndrome

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10.1038/NG.1066

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22231481

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3267865

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