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Advances in genetics: widening our understanding of prostate cancerA comparison of genetic risk score with family history for estimating prostate cancer riskInherited susceptibility for aggressive prostate cancerDevelopmental disease and cancer: biological and clinical overlapsStrategies for Imputing and Analyzing Rare Variants in Association StudiesImputation of the rare HOXB13 G84E mutation and cancer risk in a large population-based cohortIdentification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array.In Silico Analysis of the deleterious nsSNP's (missense) in the Homeobox domain of human HOXB13 gene responsible for hereditary prostate cancer.Computational Modeling of complete HOXB13 protein for predicting the functional effect of SNPs and the associated role in hereditary prostate cancer.Introduction to deep sequencing and its application to drug addiction research with a focus on rare variants.Identification and characterization of locus-specific methylation patterns within novel loci undergoing hypermethylation during breast cancer pathogenesis.Validation study of genes with hypermethylated promoter regions associated with prostate cancer recurrence.Prevalence of the HOXB13 G84E mutation among unaffected men with a family history of prostate cancerProstate cancer risk regions at 8q24 and 17q24 are differentially associated with somatic TMPRSS2:ERG fusion status.The molecular basis for ethnic variation and histological subtype differences in prostate cancer.Systems analysis of the prostate tumor suppressor NKX3.1 supports roles in DNA repair and luminal cell differentiation.Mutational landscape of candidate genes in familial prostate cancerDysregulation of the homeobox transcription factor gene HOXB13: role in prostate cancer.Prostate cancer in young men: an important clinical entity.Testing for the recurrent HOXB13 G84E germline mutation in men with clinical indications for prostate biopsyA comprehensive resequence-analysis of 250 kb region of 8q24.21 in men of African ancestryMolecular pathways and targets in prostate cancerIdentification of a novel germline SPOP mutation in a family with hereditary prostate cancer.β-catenin is required for prostate development and cooperates with Pten loss to drive invasive carcinoma.Population-based estimate of prostate cancer risk for carriers of the HOXB13 missense mutation G84E.Genome-wide testing of putative functional exonic variants in relationship with breast and prostate cancer risk in a multiethnic population.A rare 8q24 single nucleotide polymorphism (SNP) predisposes North American men to prostate cancer and possibly more aggressive diseasePutative linkage signals identified for breast cancer in African American families.Fine-mapping the HOXB region detects common variants tagging a rare coding allele: evidence for synthetic association in prostate cancer.Genome-wide association scan for variants associated with early-onset prostate cancerFine-mapping the 2q37 and 17q11.2-q22 loci for novel genes and sequence variants associated with a genetic predisposition to prostate cancerInterest in genomic SNP testing for prostate cancer risk: a pilot survey.Multiple novel prostate cancer susceptibility signals identified by fine-mapping of known risk loci among Europeans.Recurrent SKIL-activating rearrangements in ETS-negative prostate cancer.The role of HOXC6 in prostate cancer development.Common genetic variants associated with disease from genome-wide association studies are mutually exclusive in prostate cancer and rheumatoid arthritis.Germline HOXB13 p.Gly84Glu mutation and cancer susceptibility: a pooled analysis of 25 epidemiological studies with 145,257 participates.HOXB13 overexpression is an independent predictor of early PSA recurrence in prostate cancer treated by radical prostatectomyIdentification of Two Novel HOXB13 Germline Mutations in Portuguese Prostate Cancer PatientsScreening for familial and hereditary prostate cancer.
P2860
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P2860
description
2012 nî lūn-bûn
@nan
2012 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Germline mutations in HOXB13 and prostate-cancer risk
@ast
Germline mutations in HOXB13 and prostate-cancer risk
@en
Germline mutations in HOXB13 and prostate-cancer risk
@nl
type
label
Germline mutations in HOXB13 and prostate-cancer risk
@ast
Germline mutations in HOXB13 and prostate-cancer risk
@en
Germline mutations in HOXB13 and prostate-cancer risk
@nl
prefLabel
Germline mutations in HOXB13 and prostate-cancer risk
@ast
Germline mutations in HOXB13 and prostate-cancer risk
@en
Germline mutations in HOXB13 and prostate-cancer risk
@nl
P2093
P2860
P3181
P356
P1476
Germline mutations in HOXB13 and prostate-cancer risk
@en
P2093
Anna M Ray
Charles M Ewing
Chris Bizon
Christiane M Robbins
David W Craig
Dorhyun Johng
Ethan M Lange
Guifang Yan
James E Montie
John D Carpten
P2860
P3181
P356
10.1056/NEJMOA1110000
P407
P577
2012-01-12T00:00:00Z