High-affinity binders selected from designed ankyrin repeat protein libraries
about
CD4-specific designed ankyrin repeat proteins are novel potent HIV entry inhibitors with unique characteristicsRemodeling a DNA-binding protein as a specific in vivo inhibitor of bacterial secretin PulDSequence variation in ligand binding sites in proteinsTargeting extracellular domains D4 and D7 of vascular endothelial growth factor receptor 2 reveals allosteric receptor regulatory sitesToward a magic or imaginary bullet? Ligands for drug targeting to cancer cells: principles, hopes, and challengesStructure of thermally activated TRP channelsA historical perspective on protein crystallization from 1840 to the present dayDrug export pathway of multidrug exporter AcrB revealed by DARPin inhibitorsStructural consequences of mutations in interfacial Tyr residues of a protein antigen-antibody complex. The case of HyHEL-10-HELHigh-affinity single-domain binding proteins with a binary-code interfaceStructural insights into an equilibrium folding intermediate of an archaeal ankyrin repeat proteinCrystal Structure of the BARD1 Ankyrin Repeat Domain and Its Functional ConsequencesCrystal Structure and Function of a DARPin Neutralizing Inhibitor of Lactococcal Phage TP901-1: COMPARISON OF DARPin AND CAMELID VHH BINDING MODEStructural Basis of Chemokine Sequestration by a Tick Chemokine Binding Protein: The Crystal Structure of the Complex between Evasin-1 and CCL3Structure Function Studies of Vaccinia Virus Host Range Protein K1 Reveal a Novel Functional Surface for Ankyrin Repeat ProteinsA designed ankyrin repeat protein selected to bind to tubulin caps the microtubule plus endStructural and functional analysis of phosphorylation-specific binders of the kinase ERK from designed ankyrin repeat protein librariesTeaching an Old Scaffold New Tricks: Monobodies Constructed Using Alternative Surfaces of the FN3 ScaffoldDevelopment of a generic adenovirus delivery system based on structure-guided design of bispecific trimeric DARPin adaptersDesign of a binding scaffold based on variable lymphocyte receptors of jawless vertebrates by module engineeringStructure-Based Rational Design of a Toll-like Receptor 4 (TLR4) Decoy Receptor with High Binding Affinity for a Target ProteinDesign, construction, and characterization of a second-generation DARPin library with reduced hydrophobicitySelection of Specific Protein Binders for Pre-Defined Targets from an Optimized Library of Artificial Helicoidal Repeat Proteins (alphaRep)Tracking Molecular Recognition at the Atomic Level with a New Protein Scaffold Based on the OB-FoldStructure of a kinesin-tubulin complex and implications for kinesin motilityCombined inhibition of caspase 3 and caspase 7 by two highly selective DARPins slows down cellular demiseNanomedicines based on recombinant fusion proteins for targeting therapeutic siRNA oligonucleotides.TRPV4 channel activity is modulated by direct interaction of the ankyrin domain to PI(4,5)P₂The structure of apo-kinesin bound to tubulin links the nucleotide cycle to movementArtificial affinity proteins as ligands of immunoglobulinsEngineering of recombinant crystallization chaperonesCrystal structures of MBP fusion proteinsStreamlined protocol for mRNA displayTuning the drug efflux activity of an ABC transporter in vivo by in vitro selected DARPin bindersAmyloid-β peptide-specific DARPins as a novel class of potential therapeutics for Alzheimer diseaseConstruction of ribosome display library based on lipocalin scaffold and screening anticalins with specificity for estradiol.Ubiquitin is a versatile scaffold protein for the generation of molecules with de novo binding and advantageous drug-like propertiesExpansion of protein domain repeatsA stringent test for hydrophobicity scales: two proteins with 88% sequence identity but different structure and functionRational design of α-helical tandem repeat proteins with closed architectures
P2860
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P2860
High-affinity binders selected from designed ankyrin repeat protein libraries
description
2004 nî lūn-bûn
@nan
2004 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
High-affinity binders selected from designed ankyrin repeat protein libraries
@ast
High-affinity binders selected from designed ankyrin repeat protein libraries
@en
High-affinity binders selected from designed ankyrin repeat protein libraries
@nl
type
label
High-affinity binders selected from designed ankyrin repeat protein libraries
@ast
High-affinity binders selected from designed ankyrin repeat protein libraries
@en
High-affinity binders selected from designed ankyrin repeat protein libraries
@nl
prefLabel
High-affinity binders selected from designed ankyrin repeat protein libraries
@ast
High-affinity binders selected from designed ankyrin repeat protein libraries
@en
High-affinity binders selected from designed ankyrin repeat protein libraries
@nl
P2093
P2860
P3181
P356
P1433
P1476
High-affinity binders selected from designed ankyrin repeat protein libraries
@en
P2093
Andreas Kohl
Christophe Briand
H Kaspar Binz
Markus G Grütter
Michael T Stumpp
Patrick Amstutz
Patrik Forrer
P2860
P2888
P304
P3181
P356
10.1038/NBT962
P407
P577
2004-05-01T00:00:00Z
P5875
P6179
1005158698