Cutting edge: IL-21 is a switch factor for the production of IgG1 and IgG3 by human B cells
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A Temporal Model of Human IgE and IgG Antibody FunctionThe role of the T follicular helper cells in allergic diseaseThe role of interleukin-21 in HIV infectionAntibody Subclass Repertoire and Graft Outcome Following Solid Organ TransplantationThe Biological Effects of IL-21 Signaling on B-Cell-Mediated Responses in Organ TransplantationInterleukin-21: a modulator of lymphoid proliferation, apoptosis and differentiationLineages of human T-cell clones, including T helper 17/T helper 1 cells, isolated at different stages of anti-factor VIII immune responses.Exosomes derived from Burkitt's lymphoma cell lines induce proliferation, differentiation, and class-switch recombination in B cells.Phenotypic characterization of autoreactive B cells--checkpoints of B cell tolerance in patients with systemic lupus erythematosusB cell-intrinsic signaling through IL-21 receptor and STAT3 is required for establishing long-lived antibody responses in humans.Production of IgG antibodies to pneumococcal polysaccharides is associated with expansion of ICOS+ circulating memory T follicular-helper cells which is impaired by HIV infection.Molecular signatures to improve diagnosis in peripheral T-cell lymphoma and prognostication in angioimmunoblastic T-cell lymphoma.IL-21 acts directly on B cells to regulate Bcl-6 expression and germinal center responses.BMP-7 induces apoptosis in human germinal center B cells and is influenced by TGF-β receptor type I ALK5Impaired humoral immunity in X-linked lymphoproliferative disease is associated with defective IL-10 production by CD4+ T cells.IgG subclass antibodies to human and bacterial HSP60 are not associated with disease activity and progression over time in axial spondyloarthritis.Increased frequency of circulating IL-21 producing Th-cells in patients with granulomatosis with polyangiitis (GPA).IL-21 receptor signalling partially mediates Th2-mediated allergic airway responsesNew paradigms for functional HIV-specific nonneutralizing antibodiesIL-6 is required for airway mucus production induced by inhaled fungal allergensIL-21 deficiency influences CD8 T cell quality and recall responses following an acute viral infectionExpansion or depletion of T follicular helper cells during HIV infection: consequences for B cell responses.The Memories of NK Cells: Innate-Adaptive Immune Intrinsic Crosstalk.Interleukin-21 induces T-cell activation and proinflammatory cytokine secretion in rheumatoid arthritis.Human blood CXCR5(+)CD4(+) T cells are counterparts of T follicular cells and contain specific subsets that differentially support antibody secretion.Interleukin-21 augments the efficacy of T-cell therapy by eliciting concurrent cellular and humoral responses.The IL-21 receptor augments Th2 effector function and alternative macrophage activationAnalysis of the role of IL-21 in development of murine B cell progenitors in the bone marrow.IL-21 ensures TGF-beta 1-induced IgA isotype expression in mouse Peyer's patches.Human tonsil B-cell lymphoma 6 (BCL6)-expressing CD4+ T-cell subset specialized for B-cell help outside germinal centers.Upregulation of IL-21 receptor on B cells and IL-21 secretion distinguishes novel 2009 H1N1 vaccine responders from nonresponders among HIV-infected persons on combination antiretroviral therapy.The important role of T cells and receptor expression in Sjögren's syndrome.The current concept of T (h) 17 cells and their expanding role in systemic lupus erythematosus.Interleukin-21 administration to rhesus macaques chronically infected with simian immunodeficiency virus increases cytotoxic effector molecules in T cells and NK cells and enhances B cell function without increasing immune activation or viral replicDual regulation of IRF4 function in T and B cells is required for the coordination of T-B cell interactions and the prevention of autoimmunity.Divide and conquer: the importance of cell division in regulating B-cell responses.Autoregulatory function of interleukin-10-producing pre-naïve B cells is defective in systemic lupus erythematosusInborn errors of human JAKs and STATs.Opposing roles of STAT1 and STAT3 in IL-21 function in CD4+ T cellsIL-21 is the primary common γ chain-binding cytokine required for human B-cell differentiation in vivo.
P2860
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P2860
Cutting edge: IL-21 is a switch factor for the production of IgG1 and IgG3 by human B cells
description
2004 nî lūn-bûn
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2004 թուականի Մայիսին հրատարակուած գիտական յօդուած
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2004 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Cutting edge: IL-21 is a switc ...... IgG1 and IgG3 by human B cells
@ast
Cutting edge: IL-21 is a switc ...... IgG1 and IgG3 by human B cells
@en
Cutting edge: IL-21 is a switc ...... IgG1 and IgG3 by human B cells
@nl
type
label
Cutting edge: IL-21 is a switc ...... IgG1 and IgG3 by human B cells
@ast
Cutting edge: IL-21 is a switc ...... IgG1 and IgG3 by human B cells
@en
Cutting edge: IL-21 is a switc ...... IgG1 and IgG3 by human B cells
@nl
prefLabel
Cutting edge: IL-21 is a switc ...... IgG1 and IgG3 by human B cells
@ast
Cutting edge: IL-21 is a switc ...... IgG1 and IgG3 by human B cells
@en
Cutting edge: IL-21 is a switc ...... IgG1 and IgG3 by human B cells
@nl
P2093
P3181
P1476
Cutting edge: IL-21 is a switc ...... IgG1 and IgG3 by human B cells
@en
P2093
Adriana Delwail
Don Foster
Elodie Drouet
Jean-Claude Lecron
Jean-François Gauchat
Jérôme Pène
Paul Guglielmi
Sandrine Lécart
Vera Boulay
P304
P3181
P356
10.4049/JIMMUNOL.172.9.5154
P407
P50
P577
2004-05-01T00:00:00Z