Dimerization-induced inhibition of receptor protein tyrosine phosphatase function through an inhibitory wedge
about
Pleiotrophin signals increased tyrosine phosphorylation of beta beta-catenin through inactivation of the intrinsic catalytic activity of the receptor-type protein tyrosine phosphatase beta/zetaIntramolecular interactions between the juxtamembrane domain and phosphatase domains of receptor protein-tyrosine phosphatase RPTPmu. Regulation of catalytic activityProtein tyrosine phosphatase CD148-mediated inhibition of T-cell receptor signal transduction is associated with reduced LAT and phospholipase Cgamma1 phosphorylationSubdomain X of the kinase domain of Lck binds CD45 and facilitates dephosphorylationIntegrin CD11a cytoplasmic tail interacts with the CD45 membrane-proximal protein tyrosine phosphatase domain 1The conserved immunoglobulin domain controls the subcellular localization of the homophilic adhesion receptor protein-tyrosine phosphatase muA novel mechanism for Wnt activation of canonical signaling through the LRP6 receptorPositive and negative regulation of T-cell activation through kinases and phosphatasesGenomic organization and alternative splicing of the human and mouse RPTPrho genesCrystal structure of 12-oxophytodienoate reductase 3 from tomato: self-inhibition by dimerizationDimerization of receptor protein-tyrosine phosphatase alpha in living cellsCellular biochemistry methods for investigating protein tyrosine phosphatasesMultiple interactions between receptor protein-tyrosine phosphatase (RPTP) alpha and membrane-distal protein-tyrosine phosphatase domains of various RPTPsMultimerization of the protein-tyrosine phosphatase (PTP)-like insulin-dependent diabetes mellitus autoantigens IA-2 and IA-2beta with receptor PTPs (RPTPs). Inhibition of RPTPalpha enzymatic activityIntra- and intermolecular interactions between intracellular domains of receptor protein-tyrosine phosphatasesThe MAM (meprin/A5-protein/PTPmu) domain is a homophilic binding site promoting the lateral dimerization of receptor-like protein-tyrosine phosphatase muRedox regulation of dimerization of the receptor protein-tyrosine phosphatases RPTPalpha, LAR, RPTPmu and CD45Protein tyrosine phosphatases and the immune responseReciprocal regulation of lymphocyte activation by tyrosine kinases and phosphatasesTwo mechanisms activate PTPalpha during mitosisDimerization inhibits the activity of receptor-like protein-tyrosine phosphatase-alphaDimerization in vivo and inhibition of the nonreceptor form of protein tyrosine phosphatase epsilonCD45 ectodomain controls interaction with GEMs and Lck activity for optimal TCR signalingProtein tyrosine phosphatase receptor type Z is inactivated by ligand-induced oligomerizationGain control of N-methyl-D-aspartate receptor activity by receptor-like protein tyrosine phosphatase alphaDimerization of tyrosine phosphatase PTPRO decreases its activity and ability to inactivate TrkCRegulation of insulin granule turnover in pancreatic beta-cells by cleaved ICA512.Phosphorylation of CD45 by casein kinase 2. Modulation of activity and mutational analysis.A monoclonal antibody against CD148, a receptor-like tyrosine phosphatase, inhibits endothelial-cell growth and angiogenesisAn extracellular ligand increases the specific activity of the receptor-like protein tyrosine phosphatase DEP-1.Transmembrane homodimerization of receptor-like protein tyrosine phosphatases.Involvement of glycoreceptors in galactoxylomannan-induced T cell death.Role of protein phosphatases in the regulation of human mast cell and basophil function.Receptor-like protein tyrosine phosphatase alpha homodimerizes on the cell surface.Structural and evolutionary relationships among protein tyrosine phosphatase domainsSelected glimpses into the activation and function of Src kinase.T cells modulate glycans on CD43 and CD45 during development and activation, signal regulation, and survival.The biology of CD45 and its use as a therapeutic target.CD45, CD148, and Lyp/Pep: critical phosphatases regulating Src family kinase signaling networks in immune cellsLiprin-alpha has LAR-independent functions in R7 photoreceptor axon targeting
P2860
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P2860
Dimerization-induced inhibition of receptor protein tyrosine phosphatase function through an inhibitory wedge
description
1998 nî lūn-bûn
@nan
1998 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Dimerization-induced inhibitio ...... on through an inhibitory wedge
@ast
Dimerization-induced inhibitio ...... on through an inhibitory wedge
@en
Dimerization-induced inhibitio ...... on through an inhibitory wedge
@nl
type
label
Dimerization-induced inhibitio ...... on through an inhibitory wedge
@ast
Dimerization-induced inhibitio ...... on through an inhibitory wedge
@en
Dimerization-induced inhibitio ...... on through an inhibitory wedge
@nl
prefLabel
Dimerization-induced inhibitio ...... on through an inhibitory wedge
@ast
Dimerization-induced inhibitio ...... on through an inhibitory wedge
@en
Dimerization-induced inhibitio ...... on through an inhibitory wedge
@nl
P2093
P1433
P1476
Dimerization-induced inhibitio ...... on through an inhibitory wedge
@en
P2093
P356
10.1126/SCIENCE.279.5347.88
P407
P577
1998-01-02T00:00:00Z