Heat shock protein 90α (Hsp90α) is phosphorylated in response to DNA damage and accumulates in repair foci - Wikidata - wikimedia - TriplyDB

Heat shock protein 90α (Hsp90α) is phosphorylated in response to DNA damage and accumulates in repair foci

Heat shock protein 90α (Hsp90α) is phosphorylated in response to DNA damage and accumulates in repair foci

http://www.wikidata.org/entity/Q28257991

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Mechanisms of Hsp90 regulation Hsp90: A New Player in DNA Repair?DNA-PK: a dynamic enzyme in a versatile DSB repair pathway Genotypic characteristics of resistant tumors to pre-operative ionizing radiation in rectal cancer RNF144A, an E3 ubiquitin ligase for DNA-PKcs, promotes apoptosis during DNA damage DNA-PK target identification reveals novel links between DNA repair signaling and cytoskeletal regulation Regulation and function of the human HSP90AA1 gene Regulation of stress-inducible phosphoprotein 1 nuclear retention by protein inhibitor of activated STAT PIAS1.Kinesin KIFC1 actively transports bare double-stranded DNA.Effects of obesogenic diet and estradiol on dorsal raphe gene expression in old female macaques HSP90 regulates DNA repair via the interaction between XRCC1 and DNA polymerase β Ovarian steroids regulate gene expression related to DNA repair and neurodegenerative diseases in serotonin neurons of macaques.The HSP90 inhibitor ganetespib: A potential effective agent for Acute Myeloid Leukemia in combination with cytarabine Quantitative proteomics of the yeast Hsp70/Hsp90 interactomes during DNA damage reveal chaperone-dependent regulation of ribonucleotide reductase.The HSP90 Inhibitor Ganetespib Radiosensitizes Human Lung Adenocarcinoma Cells.Safety control for apoptotic irreversibility Heat shock protein 90α (HSP90α), a substrate and chaperone of DNA-PK necessary for the apoptotic response.Protein phosphatase 2A and DNA-dependent protein kinase are involved in mediating rapamycin-induced Akt phosphorylation.Increased extracellular heat shock protein 90α in severe sepsis and SIRS associated with multiple organ failure and related to acute inflammatory-metabolic stress response in children Hsp90, an unlikely ally in the war on cancer.Hyperthermia enhances 17-DMAG efficacy in hepatocellular carcinoma cells with aggravated DNA damage and impaired G2/M transition HSP90 inhibition sensitizes head and neck cancer to platin-based chemoradiotherapy by modulation of the DNA damage response resulting in chromosomal fragmentation.Reverse the Resistance to PARP Inhibitors.Localisation Microscopy of Breast Epithelial ErbB-2 Receptors and Gap Junctions: Trafficking after γ-Irradiation, Neuregulin-1β, and Trastuzumab Application.ATM is the primary kinase responsible for phosphorylation of Hsp90α after ionizing radiation Detection and repair of ionizing radiation-induced DNA double strand breaks: new developments in nonhomologous end joining.Targeting Hsp90 and its co-chaperones to treat Alzheimer's disease Centrosomes at M phase act as a scaffold for the accumulation of intracellular ubiquitinated proteins.Characterization of LGALS3 (galectin-3) as a player in DNA damage response.Regulatory Mechanisms of Hsp90.Both the charged linker region and ATPase domain of Hsp90 are essential for Rad51-dependent DNA repair.DNA-PK Promotes the Mitochondrial, Metabolic, and Physical Decline that Occurs During Aging.Cdc7-Dbf4-mediated phosphorylation of HSP90-S164 stabilizes HSP90-HCLK2-MRN complex to enhance ATR/ATM signaling that overcomes replication stress in cancer.Magnetic hyperthermia therapy for the treatment of glioblastoma: a review of the therapy's history, efficacy, and application in humans.Heat shock proteins and DNA repair mechanisms: an updated overview.The role of DNA-PK in aging and energy metabolism.Hsp90α regulates ATM and NBN functions in sensing and repair of DNA double-strand breaks.

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Heat shock protein 90α (Hsp90α) is phosphorylated in response to DNA damage and accumulates in repair foci

http://www.wikidata.org/entity/Q28257991

description

2012 nî lūn-bûn

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2012 թուականի Մարտին հրատարակուած գիտական յօդուած

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2012 թվականի մարտին հրատարակված գիտական հոդված

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年论文

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Heat shock protein 90α (Hsp90α ...... and accumulates in repair foci

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Heat shock protein 90α (Hsp90α ...... and accumulates in repair foci

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Heat shock protein 90α (Hsp90α ...... and accumulates in repair foci

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Heat shock protein 90α (Hsp90α ...... and accumulates in repair foci

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Heat shock protein 90α (Hsp90α ...... and accumulates in repair foci

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Heat shock protein 90α (Hsp90α ...... and accumulates in repair foci

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Heat shock protein 90α (Hsp90α ...... and accumulates in repair foci

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Heat shock protein 90α (Hsp90α ...... and accumulates in repair foci

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Heat shock protein 90α (Hsp90α ...... and accumulates in repair foci

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JBC.M111.320887

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Journal of Biological Chemistry

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Heat shock protein 90α (Hsp90α ...... and accumulates in repair foci

@en

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Aurélie Herbette

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Jian-Sheng Sun

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Leanne de Koning

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Mano Sayarath

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Maria Quanz

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Marie Dutreix

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P2860

Hyperactivation of DNA-PK by double-strand break mimicking molecules disorganizes DNA damage response

The mechanism of double-strand DNA break repair by the nonhomologous DNA end-joining pathway

MDC1 directly binds phosphorylated histone H2AX to regulate cellular responses to DNA double-strand breaks

ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage

Protein Tpr is required for establishing nuclear pore-associated zones of heterochromatin exclusion

Secreted heat shock protein 90alpha induces colorectal cancer cell invasion through CD91/LRP-1 and NF-kappaB-mediated integrin alphaV expression

The ATPase cycle of Hsp90 drives a molecular 'clamp' via transient dimerization of the N-terminal domains

Dynamics of DNA damage response proteins at DNA breaks: a focus on protein modifications

Trex1 prevents cell-intrinsic initiation of autoimmunity

The DNA Damage Response: Making It Safe to Play with Knives

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10.1074/JBC.M111.320887

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12

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287

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22270370

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phosphorylation

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3308794

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