S-nitrosylation of parkin regulates ubiquitination and compromises parkin's protective function
about
S-nitrosylation of Bcl-2 inhibits its ubiquitin-proteasomal degradation - a novel antiapoptotic mechanism that suppresses apoptosisPARIS (ZNF746) repression of PGC-1α contributes to neurodegeneration in Parkinson's diseaseTRIM9, a novel brain-specific E3 ubiquitin ligase, is repressed in the brain of Parkinson's disease and dementia with Lewy bodiesLeucine-rich repeat kinase 2 (LRRK2) interacts with parkin, and mutant LRRK2 induces neuronal degeneration.Phosphorylation by the c-Abl protein tyrosine kinase inhibits parkin's ubiquitination and protective functionAutoregulation of Parkin activity through its ubiquitin-like domainThe role of oxidative stress in Parkinson's diseaseParkin-dependent degradation of the F-box protein Fbw7β promotes neuronal survival in response to oxidative stress by stabilizing Mcl-1ATF4 protects against neuronal death in cellular Parkinson's disease models by maintaining levels of parkinProgrammed cell death-2 isoform1 is ubiquitinated by parkin and increased in the substantia nigra of patients with autosomal recessive Parkinson's diseaseProtein microarray characterization of the S-nitrosoproteomeDopamine covalently modifies and functionally inactivates parkinStructure and Function of Parkin, PINK1, and DJ-1, the Three Musketeers of NeuroprotectionSignaling by gasotransmittersUbiquitin phosphorylation in Parkinson's disease: Implications for pathogenesis and treatmentImplications of glial nitric oxide in neurodegenerative diseasesRBR E3 ubiquitin ligases: new structures, new insights, new questionsMechanisms of altered redox regulation in neurodegenerative diseases--focus on S--glutathionylationMolecular aspects of dopaminergic neurodegeneration: gene-environment interaction in parkin dysfunctionGasotransmitters in Gametogenesis and Early Development: Holy Trinity for Assisted Reproductive Technology-A ReviewGene-environment interactions in Parkinson's disease: specific evidence in humans and mammalian modelsPathologic and therapeutic implications for the cell biology of parkinMitochondria and mitophagy: the yin and yang of cell death controlNitric oxide destabilizes Pias3 and regulates sumoylationCell-permeable parkin proteins suppress Parkinson disease-associated phenotypes in cultured cells and animalsParkin promotes proteasomal degradation of p62: implication of selective vulnerability of neuronal cells in the pathogenesis of Parkinson's diseaseStructure of the Parkin in-between-ring domain provides insights for E3-ligase dysfunction in autosomal recessive Parkinson's diseaseExploration of the Active Site of Neuronal Nitric Oxide Synthase by the Design and Synthesis of Pyrrolidinomethyl 2-Aminopyridine DerivativesInsights into BAY 60-2770 Activation and S -Nitrosylation-Dependent Desensitization of Soluble Guanylyl Cyclase via Crystal Structures of Homologous Nostoc H-NOX Domain Complexes14-3-3eta is a novel regulator of parkin ubiquitin ligase.S-Nitrosylation of parkin as a novel regulator of p53-mediated neuronal cell death in sporadic Parkinson's diseaseThe parkin-like human homolog of Drosophila ariadne-1 (HHARI) can induce aggresome formation in mammalian cells and is immunologically detectable in Lewy bodiesIdentification of far upstream element-binding protein-1 as an authentic Parkin substrateThe branched-chain aminotransferase proteins: novel redox chaperones for protein disulfide isomerase--implications in Alzheimer's diseaseNitrosothiol signaling and protein nitrosation in cell deathMDA-7/IL-24 induces Bcl-2 denitrosylation and ubiquitin-degradation involved in cancer cell apoptosisModes of physiologic H2S signaling in the brain and peripheral tissuesGene-environment interactions: key to unraveling the mystery of Parkinson's diseaseStriatal neuroinflammation promotes Parkinsonism in ratsParkin deficiency delays motor decline and disease manifestation in a mouse model of synucleinopathy
P2860
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P2860
S-nitrosylation of parkin regulates ubiquitination and compromises parkin's protective function
description
2004 nî lūn-bûn
@nan
2004 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
S-nitrosylation of parkin regu ...... s parkin's protective function
@ast
S-nitrosylation of parkin regu ...... s parkin's protective function
@en
S-nitrosylation of parkin regu ...... s parkin's protective function
@nl
type
label
S-nitrosylation of parkin regu ...... s parkin's protective function
@ast
S-nitrosylation of parkin regu ...... s parkin's protective function
@en
S-nitrosylation of parkin regu ...... s parkin's protective function
@nl
prefLabel
S-nitrosylation of parkin regu ...... s parkin's protective function
@ast
S-nitrosylation of parkin regu ...... s parkin's protective function
@en
S-nitrosylation of parkin regu ...... s parkin's protective function
@nl
P2093
P3181
P356
P1433
P1476
S-nitrosylation of parkin regu ...... s parkin's protective function
@en
P2093
Bobby Thomas
Juan C Troncoso
Kenny K K Chung
Laura Marsh
Olga Pletnikova
Valina L Dawson
Xiaojie Li
P304
P3181
P356
10.1126/SCIENCE.1093891
P407
P577
2004-05-28T00:00:00Z