Mutations in the BRCA1-associated RING domain (BARD1) gene in primary breast, ovarian and uterine cancers - Wikidata - wikimedia - TriplyDB

Mutations in the BRCA1-associated RING domain (BARD1) gene in primary breast, ovarian and uterine cancers

Mutations in the BRCA1-associated RING domain (BARD1) gene in primary breast, ovarian and uterine cancers

http://www.wikidata.org/entity/Q28258544

about

Function of BRCA1 in the DNA damage response is mediated by ADP-ribosylation BARD1 induces apoptosis by catalysing phosphorylation of p53 by DNA-damage response kinase Estrogen receptor alpha regulates expression of the breast cancer 1 associated ring domain 1 (BARD1) gene through intronic DNA sequence Cancer incidence in relatives of a population-based set of cases of early-onset breast cancer with a known BRCA1 and BRCA2 mutation status Aberrations of TACC1 and TACC3 are associated with ovarian cancer The role of poly(ADP-ribosyl)ation in DNA damage response and cancer chemotherapy The BRCA1 Breast Cancer Suppressor: Regulation of Transport, Dynamics, and Function at Multiple Subcellular Locations Crystal Structure of the BARD1 Ankyrin Repeat Domain and Its Functional Consequences Nuclear-cytoplasmic shuttling of BARD1 contributes to its proapoptotic activity and is regulated by dimerization with BRCA1 Mutations in the RAD54 recombination gene in primary cancers The RING heterodimer BRCA1-BARD1 is a ubiquitin ligase inactivated by a breast cancer-derived mutation BARD1 induces BRCA1 intranuclear foci formation by increasing RING-dependent BRCA1 nuclear import and inhibiting BRCA1 nuclear export Phosphopeptide binding specificities of BRCA1 COOH-terminal (BRCT) domains Identification of residues required for the interaction of BARD1 with BRCA1 Enhancement of BRCA1 E3 ubiquitin ligase activity through direct interaction with the BARD1 protein Is there more to BARD1 than BRCA1?BARD1 expression during spermatogenesis is associated with apoptosis and hormonally regulated Loss of Bard1, the heterodimeric partner of the Brca1 tumor suppressor, results in early embryonic lethality and chromosomal instability BARD1 participates with BRCA1 in homology-directed repair of chromosome breaks Identification of functional SNPs in BARD1 gene and in silico analysis of damaging SNPs: based on data procured from dbSNP database The BARD1 Cys557Ser variant and breast cancer risk in Iceland The functions of breast cancer susceptibility gene 1 (BRCA1) product and its associated proteins.Structural basis to stabilize the domain motion of BARD1-ARD BRCT by CstF50.BRCA1 physically and functionally interacts with ATF1.Emerging roles of BRCA1 alternative splicing.Functional communication between endogenous BRCA1 and its partner, BARD1, during Xenopus laevis development.BRCA1 and prostate cancer.Common genetic variation at BARD1 is not associated with breast cancer risk in BRCA1 or BRCA2 mutation carriers.Association of three common BARD1 variants with cancer susceptibility: a system review and meta-analysis.Identification and characterization of missense alterations in the BRCA1 associated RING domain (BARD1) gene in breast and ovarian cancer Analysis of large mutations in BARD1 in patients with breast and/or ovarian cancer: the Polish population as an example Ubiquitin and breast cancer.BARD1 expression predicts outcome in colon cancer.Breast cancer susceptibility and the DNA damage response.In vitro repression of Brca1-associated RING domain gene, Bard1, induces phenotypic changes in mammary epithelial cells The Association between GWAS-identified BARD1 Gene SNPs and Neuroblastoma Susceptibility in a Southern Chinese Population.The basal-like mammary carcinomas induced by Brca1 or Bard1 inactivation implicate the BRCA1/BARD1 heterodimer in tumor suppression.Nordic collaborative study of the BARD1 Cys557Ser allele in 3956 patients with cancer: enrichment in familial BRCA1/BRCA2 mutation-negative breast cancer but not in other malignancies.Recognition of DNA double strand breaks by the BRCA1 tumor suppressor network.The BARD1 C-terminal domain structure and interactions with polyadenylation factor CstF-50.

P2860

Q24293084-B9C2F638-9551-412E-ABF8-24B38F81DDEF Q24298631-F34B0A39-4BB8-4A3F-B816-9C7028396049 Q24684173-C50F5A14-99F4-4DE8-A09F-C9C5FDDC7DA4 Q24802534-B50FC9C2-2D47-449C-9F76-FD3FF314518C Q24811001-7A48C1D0-D68E-47A7-A09C-BCE18AC59612 Q27010084-1674B088-339A-4846-AFDC-1BD5923A3BBF Q27026264-A530360F-B588-475C-8723-28493F258254 Q27650617-29224431-4CB1-462E-B1C5-4D5A747EB3A2 Q28188597-35B366F0-4044-4B89-A380-9F8ABF2BB01A Q28199167-E50523BA-D83A-41DF-BB9F-8B53196291E0 Q28207617-07F65E50-5D98-423A-BFF1-B4EFD4BF3DBB Q28211710-C9EB9552-A5E6-4DF4-B836-DF0894268428 Q28212425-072A5F38-1166-46C2-89DC-277A257CE37E Q28214378-241B2A20-BA34-4C1A-852A-4658D8623710 Q28214794-22141188-AAD0-4B5F-B469-57AC356C465F Q28236135-B13F809F-9F22-4093-9CE1-B0D7A523473C Q28581513-47DD0063-1E69-46B4-9F35-549B85D3C38E Q28609929-E6A4D873-7F05-4678-B7C1-4E2B3EFE7498 Q28609933-E0C4FF6A-589A-4907-A57A-534C32D35084 Q30000832-2D18D733-0121-4156-AC1F-F0DED5C08CBB Q33246499-B3B82720-1585-49A6-B50A-FF452A3F4003 Q33589502-38EF44AD-C1E7-4DFD-968E-A2FC51DDD87D Q33818899-DF89A075-1D18-42BC-9A1F-D3413D23D1D9 Q33914215-EB68A3E1-F4C9-4419-989D-1450498F7ECD Q33919195-586353E0-5801-48CC-90B3-41C3DA91BFF4 Q33946999-4CF63636-5004-4AEE-B889-3F088CC64E17 Q34280860-0566F406-DA5F-44CB-979E-40CC5AE147ED Q34949394-2D54B379-A4B3-4791-BFD8-17FF8EC8EC15 Q35173448-179EA32A-C09D-4841-A780-BFFB72638637 Q35448920-3E25ACC8-CD79-4E71-BB59-D27F4EC575C2 Q35631708-9CA0CF2C-A51B-46CD-9FEB-5CD55A885B7B Q35691563-D3C475BA-C048-4D8F-859E-DA35BBD9960C Q36023795-11CAA5FA-39DA-431C-983B-4B26909D115E Q36108626-5C32E965-7A79-4C43-AD2A-CDFD8B60D963 Q36256353-EDC1929A-B23F-4AE2-A1C8-39FEE64719D5 Q36610631-1A60B58D-FD02-4F6E-BD7C-DEB5815B60AB Q36627600-0E6F337A-3F59-42D2-AAF4-AB63C1E2AA4A Q36927115-E912979A-21E6-4477-89C5-762BC0A473F0 Q37120275-A133FA7A-B993-490F-A291-384D72109901 Q37124472-0731A280-95A8-40E9-AD3A-25ED24653A51

P2860

Mutations in the BRCA1-associated RING domain (BARD1) gene in primary breast, ovarian and uterine cancers

http://www.wikidata.org/entity/Q28258544

description

1998 nî lūn-bûn

@nan

1998 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

1998 թվականի փետրվարին հրատարակված գիտական հոդված

@hy

1998年の論文

@ja

1998年論文

@yue

1998年論文

@zh-hant

1998年論文

@zh-hk

1998年論文

@zh-mo

1998年論文

@zh-tw

1998年论文

@wuu

name

Mutations in the BRCA1-associa ...... t, ovarian and uterine cancers

@ast

Mutations in the BRCA1-associa ...... t, ovarian and uterine cancers

@en

Mutations in the BRCA1-associa ...... t, ovarian and uterine cancers

@nl

type

label

Mutations in the BRCA1-associa ...... t, ovarian and uterine cancers

@ast

Mutations in the BRCA1-associa ...... t, ovarian and uterine cancers

@en

Mutations in the BRCA1-associa ...... t, ovarian and uterine cancers

@nl

prefLabel

Mutations in the BRCA1-associa ...... t, ovarian and uterine cancers

@ast

Mutations in the BRCA1-associa ...... t, ovarian and uterine cancers

@en

Mutations in the BRCA1-associa ...... t, ovarian and uterine cancers

@nl

P1433

Q28258544-9D69AFE9-7517-4955-AA01-C0FDE615386B

P1476

Q28258544-55961F86-7DF1-47FD-B18F-442BF929A9AD

P2093

Q28258544-0D6ABC6C-C987-4BBB-B234-F5C9016F75C3

Q28258544-2558CDCF-AB51-4925-8E01-A47928BF43CC

Q28258544-272DAE3D-9F09-4D1F-A956-B527DB3AA404

Q28258544-3BE822B5-7125-4289-AD0B-46F4A97C7D2E

Q28258544-58F10F08-8C85-4C15-9A33-D4EBB45D78DF

Q28258544-8133628C-F794-4411-B66F-E3F395E1AD67

Q28258544-A316C68C-EA2C-4890-B99F-8528CA57B8E5

Q28258544-A3B50708-B9D8-4E1B-B4EA-60D963C58758

Q28258544-AF76C76B-AA30-4CFC-B1A1-F2BC3442BEFA

Q28258544-BBB53F27-52C4-4110-A333-4DFE6E8E7ECA

P304

Q28258544-504DB4BB-A706-48BC-9995-5D7C6C09FA09

P31

Q28258544-899F4477-AE49-45E1-A964-57A136B341CE

P356

Q28258544-705E52AD-3971-439C-9AFC-A64879CD9955

P407

Q28258544-D2776181-981B-4D95-AE10-2FF47F29010C

P433

Q28258544-3E6306DA-8DC1-44A1-867B-DFFEC15D71EB

P478

Q28258544-FA64FDCF-8965-4C2E-AE39-A2A0BFD89B00

P577

Q28258544-29F44107-881F-40A6-A652-56F4F45AA10B

P5875

Q28258544-AE9400BD-A3C0-434D-BC77-F80301040EF3

P698

Q28258544-79EEBD05-DA46-4017-A48E-6DB55C19EA34

P356

P1433

Human Molecular Genetics

P1476

Mutations in the BRCA1-associa ...... t, ovarian and uterine cancers

@en

P2093

A M Bowcock

http://www.w3.org/2001/XMLSchema#string

A Phung

http://www.w3.org/2001/XMLSchema#string

B J Trask

http://www.w3.org/2001/XMLSchema#string

C Y Muller

http://www.w3.org/2001/XMLSchema#string

D S Miller

http://www.w3.org/2001/XMLSchema#string

F Du

http://www.w3.org/2001/XMLSchema#string

H F Massa

http://www.w3.org/2001/XMLSchema#string

J M Mathis

http://www.w3.org/2001/XMLSchema#string

J T Tsan

http://www.w3.org/2001/XMLSchema#string

M A Spillman

http://www.w3.org/2001/XMLSchema#string

P304

195-202

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1093/HMG/7.2.195

http://www.w3.org/2001/XMLSchema#string

P407

P433

2

http://www.w3.org/2001/XMLSchema#string

P478

7

http://www.w3.org/2001/XMLSchema#string

P577

1998-02-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

279610432

http://www.w3.org/2001/XMLSchema#string

P698

9425226

http://www.w3.org/2001/XMLSchema#string