Structural model of MD-2 and functional role of its basic amino acid clusters involved in cellular lipopolysaccharide recognition
about
Allergenicity resulting from functional mimicry of a Toll-like receptor complex proteinCrystal structures of human MD-2 and its complex with antiendotoxic lipid IVaHow exposures to biologics influence the induction and incidence of asthmaToll-like receptors: structural pieces of a curve-shaped puzzle.The differential interaction of Brucella and ochrobactrum with innate immunity reveals traits related to the evolution of stealthy pathogensSOCS2 influences LPS induced human monocyte-derived dendritic cell maturation.Transcriptional responses in honey bee larvae infected with chalkbrood fungus.Synthetic toll-like receptor 4 agonists stimulate innate resistance to infectious challenge.Novel roles of lysines 122, 125, and 58 in functional differences between human and murine MD-2.Prothymosin-alpha inhibits HIV-1 via Toll-like receptor 4-mediated type I interferon induction.N-linked glycosylation at Asn3 and the positively charged residues within the amino-terminal domain of the c1 inhibitor are required for interaction of the C1 Inhibitor with Salmonella enterica serovar typhimurium lipopolysaccharide and lipid A.Partially glycosylated dendrimers block MD-2 and prevent TLR4-MD-2-LPS complex mediated cytokine responses.Mite allergen Der-p2 triggers human B lymphocyte activation and Toll-like receptor-4 induction.Host transcription factors in the immediate pro-inflammatory response to the parasitic mite Psoroptes ovis.Early steps in steroidogenesis: intracellular cholesterol trafficking.LPS ligand and culture additives improve production of monomeric MD-1 and 2 in Pichia pastoris by decreasing aggregation and intermolecular disulfide bondingToll-like receptor-mediated responses by placental Hofbauer cells (HBCs): a potential pro-inflammatory role for fetal M2 macrophagesStructure and immunological characterization of the capsular polysaccharide of a pyrogenic liver abscess caused by Klebsiella pneumoniae: activation of macrophages through Toll-like receptor 4Modulating LPS signal transduction at the LPS receptor complex with synthetic Lipid A analoguesUnique Toll-Like Receptor 4 Activation by NAMPT/PBEF Induces NFκB Signaling and Inflammatory Lung InjuryNMR studies of hexaacylated endotoxin bound to wild-type and F126A mutant MD-2 and MD-2·TLR4 ectodomain complexes.Activation of Human Toll-like Receptor 4 (TLR4)·Myeloid Differentiation Factor 2 (MD-2) by Hypoacylated Lipopolysaccharide from a Clinical Isolate of Burkholderia cenocepaciaMechanisms of endotoxin neutralization by synthetic cationic compounds.Paclitaxel ameliorates lipopolysaccharide-induced kidney injury by binding myeloid differentiation protein-2 to block Toll-like receptor 4-mediated nuclear factor-κB activation and cytokine production.Isolation of monomeric and dimeric secreted MD-2. Endotoxin.sCD14 and Toll-like receptor 4 ectodomain selectively react with the monomeric form of secreted MD-2.MD-2 binds cholesterol.Niemann-pick type C2 deficiency in human fibroblasts confers robust and selective activation of prostaglandin E2 biosynthesis.Essential roles of hydrophobic residues in both MD-2 and toll-like receptor 4 in activation by endotoxinFree thiol group of MD-2 as the target for inhibition of the lipopolysaccharide-induced cell activationAedes aegypti ML and Niemann-Pick type C family members are agonists of dengue virus infection.New insights into innate immune mechanisms underlying allergenicity.Molecular Basis of the Functional Differences between Soluble Human Versus Murine MD-2: Role of Val135 in Transfer of Lipopolysaccharide from CD14 to MD-2.Alcoholic liver disease and the gut-liver axis.Allergen-specific pattern recognition receptor pathways.Factors influencing the allergenicity and adjuvanticity of allergens.Novel roles in human MD-2 of phenylalanines 121 and 126 and tyrosine 131 in activation of Toll-like receptor 4 by endotoxin.Toll-like receptor 4 senses oxidative stress mediated by the oxidation of phospholipids in extracellular vesicles.Paclitaxel binding to human and murine MD-2.Transfer of monomeric endotoxin from MD-2 to CD14: characterization and functional consequences.Gut-homing Δ42PD1(+)Vδ2 T cells promote innate mucosal damage via TLR4 during acute HIV type 1 infection.
P2860
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P2860
Structural model of MD-2 and functional role of its basic amino acid clusters involved in cellular lipopolysaccharide recognition
description
2004 nî lūn-bûn
@nan
2004 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Structural model of MD-2 and f ...... lipopolysaccharide recognition
@ast
Structural model of MD-2 and f ...... lipopolysaccharide recognition
@en
Structural model of MD-2 and f ...... lipopolysaccharide recognition
@nl
type
label
Structural model of MD-2 and f ...... lipopolysaccharide recognition
@ast
Structural model of MD-2 and f ...... lipopolysaccharide recognition
@en
Structural model of MD-2 and f ...... lipopolysaccharide recognition
@nl
prefLabel
Structural model of MD-2 and f ...... lipopolysaccharide recognition
@ast
Structural model of MD-2 and f ...... lipopolysaccharide recognition
@en
Structural model of MD-2 and f ...... lipopolysaccharide recognition
@nl
P2093
P356
P1476
Structural model of MD-2 and f ...... lipopolysaccharide recognition
@en
P2093
Anton Gruber
Carsten J Kirschning
Hermann Wagner
Mateja Mancek
P304
P356
10.1074/JBC.M400993200
P407
P50
P577
2004-07-02T00:00:00Z