The pleomorphic pathology of inherited Parkinson's disease: lessons from LRRK2
about
Leucine-rich repeat kinase 2 regulates Sec16A at ER exit sites to allow ER-Golgi exportLRRK2 affects vesicle trafficking, neurotransmitter extracellular level and membrane receptor localization.Selective expression of Parkinson's disease-related Leucine-rich repeat kinase 2 G2019S missense mutation in midbrain dopaminergic neurons impairs dopamine release and dopaminergic gene expression.LRRK2 and vesicle trafficking.Familial knockin mutation of LRRK2 causes lysosomal dysfunction and accumulation of endogenous insoluble α-synuclein in neurons.
P2860
The pleomorphic pathology of inherited Parkinson's disease: lessons from LRRK2
description
2006 nî lūn-bûn
@nan
2006 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
The pleomorphic pathology of inherited Parkinson's disease: lessons from LRRK2
@ast
The pleomorphic pathology of inherited Parkinson's disease: lessons from LRRK2
@en
The pleomorphic pathology of inherited Parkinson's disease: lessons from LRRK2
@nl
type
label
The pleomorphic pathology of inherited Parkinson's disease: lessons from LRRK2
@ast
The pleomorphic pathology of inherited Parkinson's disease: lessons from LRRK2
@en
The pleomorphic pathology of inherited Parkinson's disease: lessons from LRRK2
@nl
prefLabel
The pleomorphic pathology of inherited Parkinson's disease: lessons from LRRK2
@ast
The pleomorphic pathology of inherited Parkinson's disease: lessons from LRRK2
@en
The pleomorphic pathology of inherited Parkinson's disease: lessons from LRRK2
@nl
P1476
The pleomorphic pathology of inherited Parkinson's disease: lessons from LRRK2
@en
P2888
P356
10.1007/S11910-996-0013-Z
P407
P577
2006-09-01T00:00:00Z
P6179
1033350952