Leukotriene B4 receptor-2 promotes invasiveness and metastasis of ovarian cancer cells through signal transducer and activator of transcription 3 (STAT3)-dependent up-regulation of matrix metalloproteinase 2

Leukotriene B4 receptor-2 promotes invasiveness and metastasis of ovarian cancer cells through signal transducer and activator of transcription 3 (STAT3)-dependent up-regulation of matrix metalloproteinase 2

Item

http://www.wikidata.org/entity/Q28261408

Q28261408

about

BLT2 is a pro-tumorigenic mediator during cancer progression and a therapeutic target for anti-cancer drug development Current evidence linking polyunsaturated Fatty acids with cancer risk and progression Oxidative stress in cancer and fibrosis: Opportunity for therapeutic intervention with antioxidant compounds, enzymes, and nanoparticles Ras promotes transforming growth factor-β (TGF-β)-induced epithelial-mesenchymal transition via a leukotriene B4 receptor-2-linked cascade in mammary epithelial cells Myeloid differentiation primary response gene 88-leukotriene B4 receptor 2 cascade mediates lipopolysaccharide-potentiated invasiveness of breast cancer cells Activation of the leukotriene B4 receptor 2-reactive oxygen species (BLT2-ROS) cascade following detachment confers anoikis resistance in prostate cancer cells Update on leukotriene, lipoxin and oxoeicosanoid receptors: IUPHAR Review 7 Effects of RNA silencing of matrix metalloproteinase-2 on the growth of esophageal carcinoma cells in vivo NADPH oxidases: a perspective on reactive oxygen species production in tumor biology Decoding NADPH oxidase 4 expression in human tumors.ABCA transporter gene expression and poor outcome in epithelial ovarian cancer.The role of chemoattractant receptors in shaping the tumor microenvironment.BLT2 up-regulates interleukin-8 production and promotes the invasiveness of breast cancer cells Catalpol suppresses proliferation and facilitates apoptosis of OVCAR-3 ovarian cancer cells through upregulating microRNA-200 and downregulating MMP-2 expression Targeted Blockade of JAK/STAT3 Signaling Inhibits Ovarian Carcinoma Growth.Targeted tumor therapy by Rubia tinctorum L.: analytical characterization of hydroxyanthraquinones and investigation of their selective cytotoxic, adhesion and migration modulator effects on melanoma cell lines (A2058 and HT168-M1).Leukotriene receptor expression in esophageal squamous cell cancer and non-transformed esophageal epithelium: a matched case control study.LPS Up-Regulates ICAM-1 Expression in Breast Cancer Cells by Stimulating a MyD88-BLT2-ERK-Linked Cascade, Which Promotes Adhesion to Monocytes.Mechanisms of ovarian cancer metastasis: biochemical pathways.The duplicitous origin of ovarian cancer.A leukotriene B4 receptor-2 is associated with paclitaxel resistance in MCF-7/DOX breast cancer cells Polymerase delta interacting protein 2 sustains vascular structure and function.Aiding and abetting roles of NOX oxidases in cellular transformation.Are GPCRs still a source of new targets?Redox regulation of cancer metastasis: molecular signaling and therapeutic opportunities.The human Nox4: gene, structure, physiological function and pathological significance.Estrogen potentiates reactive oxygen species (ROS) tolerance to initiate carcinogenesis and promote cancer malignant transformation.Molecular mechanisms of target recognition by lipid GPCRs: relevance for cancer.Elevated STAT3 expression in ovarian cancer ascites promotes invasion and metastasis: a potential therapeutic target.Galectin-1 promotes tumor progression via NF-κB signaling pathway in epithelial ovarian cancer.Leukotriene B4 receptor 2 gene polymorphism (rs1950504, Asp196Gly) leads to enhanced cell motility under low-dose ligand stimulation.The yin and yang of leukotriene B4 mediated inflammation in cancer.

P2860

Q24631264-9E50495A-EB65-4FB4-A44D-0A0598E264B7 Q27022573-A6A6152B-F185-4B76-A99C-5D8901A85F1D Q28075551-550E185E-0800-4C29-8000-10FC8D74BB87 Q28243232-5DBDF44D-0CB0-43D2-A9B0-894B7BB8E9C3 Q28257239-F40D86BB-7ABF-477A-BD2B-D4951B6DF931 Q28297542-5504161D-C716-4EEE-967C-611C8C53036E Q28308192-F5F52650-925D-4E7A-A71A-A0ADCB691611 Q33598470-B8F338B4-430A-4301-B16B-B75B978C5764 Q33632660-598AFB50-B56B-4B05-8A25-F9A345A3E2C4 Q33761274-F9AC5067-FA1A-435D-BFE0-F7F000A1BE38 Q33947899-9B1F1DB7-AD38-4299-BA9D-0ED76038614E Q33993124-F1165856-37E0-4629-991A-7A3108032C01 Q34474210-78E30613-11A7-491A-9C76-6C33295A3AF5 Q34684928-498F8948-9C21-4864-B8F2-C6AC25E0EFC2 Q35374753-D6EB58EF-9B8C-405D-8FC2-3F4F678097EA Q35874369-D0554B7C-9594-4C8C-8EC2-34513AC22D65 Q36091008-44CF0109-154B-40AD-8BB0-9CE140E4E466 Q36107269-34FFBC1D-C29A-441E-9A6F-048EF082AB8F Q36321859-16A87BAE-38E1-40C4-AD7F-9B0B0307FF1D Q36919484-ED2EAD19-17C5-4F85-BE82-20320D4E13B6 Q37040640-DDE5CFBD-402C-4B2A-96C2-0DA942A76D37 Q37334463-2A122F6E-445F-4F82-B66D-C1976957B498 Q38037330-63A73867-199B-4B48-B0DA-D1ABA9A3A7BE Q38129012-B0D98AD0-7FDD-4697-A409-3DEB5E4BBADB Q38243631-338AB4BB-4D91-43E4-8D14-94A2FDABD410 Q38464231-8F939584-E835-42B5-8E91-E7DB38C19FB2 Q38632920-918A01DC-05C3-4CF1-80D1-E8D736C77E0B Q38660494-31676BCC-CD73-4B7C-AAEC-B0FBDC6D9112 Q41863613-F7BF828F-23F8-497C-80EF-94C5795DAE4A Q46011748-8A1ECDF0-5599-4270-AE15-83CA6B131F96 Q46255055-CF35A035-AF2F-457E-B1C4-1C88FC8CEA70 Q49573862-7F640E7A-96FE-431B-AD40-53FE86BD3E5F

P2860

Leukotriene B4 receptor-2 promotes invasiveness and metastasis of ovarian cancer cells through signal transducer and activator of transcription 3 (STAT3)-dependent up-regulation of matrix metalloproteinase 2

Item

http://www.wikidata.org/entity/Q28261408

description

2012 nî lūn-bûn

@nan

2012 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2012 թվականի ապրիլին հրատարակված գիտական հոդված

@hy

2012年の論文

@ja

2012年論文

@yue

2012年論文

@zh-hant

2012年論文

@zh-hk

2012年論文

@zh-mo

2012年論文

@zh-tw

2012年论文

@wuu