Purification, characterization, and biosynthesis of margatoxin, a component of Centruroides margaritatus venom that selectively inhibits voltage-dependent potassium channels
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Kv1.3 potassium channels are localized in the immunological synapse formed between cytotoxic and target cellsK+ channels as targets for specific immunomodulationScorpions from Mexico: From Species Diversity to Venom ComplexityComputational Studies of Venom Peptides Targeting Potassium ChannelsThe Gatekeepers in the Mouse Ophthalmic Artery: Endothelium-Dependent Mechanisms of Cholinergic Vasodilation.Structural and functional consequences of the presence of a fourth disulfide bridge in the scorpion short toxins: Solution structure of the potassium channel inhibitor HsTX1Potent suppression of vascular smooth muscle cell migration and human neointimal hyperplasia by KV1.3 channel blockersRole of Kv1 potassium channels in regulating dopamine release and presynaptic D2 receptor functionThe antibody targeting the E314 peptide of human Kv1.3 pore region serves as a novel, potent and specific channel blockerRecombinant expression of margatoxin and agitoxin-2 in Pichia pastoris: an efficient method for production of KV1.3 channel blockersCharacterization of voltage-gated potassium channels in human neural progenitor cellsPredominant functional expression of Kv1.3 by activated microglia of the hippocampus after Status epilepticus.Molecular diversity and regulation of renal potassium channels.Binding modes of two scorpion toxins to the voltage-gated potassium channel kv1.3 revealed from molecular dynamics.Potassium secretion by voltage-gated potassium channel Kv1.3 in the rat kidneyMature and precursor brain-derived neurotrophic factor have individual roles in the mouse olfactory bulbComputational simulations of interactions of scorpion toxins with the voltage-gated potassium ion channel.Stimulation of glucose uptake in murine soleus muscle and adipocytes by 5-(4-phenoxybutoxy)psoralen (PAP-1) may be mediated by Kv1.5 rather than Kv1.3.Blockade of Kv1.3 potassium channels inhibits differentiation and granzyme B secretion of human CD8+ T effector memory lymphocytes.Potent suppression of Kv1.3 potassium channel and IL-2 secretion by diphenyl phosphine oxide-1 in human T cells.Immunomodulatory effects of the Tityus serrulatus venom on murine macrophage functions in vitro.Comparison of modulation of Kv1.3 channel by two receptor tyrosine kinases in olfactory bulb neurons of rodents.Shaker-type Kv1 channel blockers increase the peristaltic activity of guinea-pig ileum by stimulating acetylcholine and tachykinins release by the enteric nervous system.Postnatal development of A-type and Kv1- and Kv2-mediated potassium channel currents in neocortical pyramidal neurons.Kv1.3 channels regulate synaptic transmission in the nucleus of solitary tractFunctional unit size of the charybdotoxin receptor in smooth muscle.Expression and function of a CP339,818-sensitive K⁺ current in a subpopulation of putative nociceptive neurons from adult mouse trigeminal ganglia.The Lymphocyte Potassium Channels Kv1.3 and KCa3.1 as Targets for Immunosuppression.Toxins Targeting the Kv1.3 Channel: Potential Immunomodulators for Autoimmune DiseasesKv1 channels and neural processing in vestibular calyx afferents.Analogs of the sea anemone potassium channel blocker ShK for the treatment of autoimmune diseases.Rituximab inhibits Kv1.3 channels in human B lymphoma cells via activation of FcγRIIB receptorsVm24, a natural immunosuppressive peptide, potently and selectively blocks Kv1.3 potassium channels of human T cells.Selective inhibition of CCR7(-) effector memory T cell activation by a novel peptide targeting Kv1.3 channel in a rat experimental autoimmune encephalomyelitis modelCeramide-induced inhibition of T lymphocyte voltage-gated potassium channel is mediated by tyrosine kinases.Kv1.3 channels in postganglionic sympathetic neurons: expression, function, and modulation.Biochemical and electrophysiological characterization of two sea anemone type 1 potassium toxins from a geographically distant population of Bunodosoma caissarum.Participation of Kv1 channels in control of membrane excitability and burst generation in mesencephalic V neurons.K+ channel modulators for the treatment of neurological disorders and autoimmune diseasesThe functional network of ion channels in T lymphocytes
P2860
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P2860
Purification, characterization, and biosynthesis of margatoxin, a component of Centruroides margaritatus venom that selectively inhibits voltage-dependent potassium channels
description
1993 nî lūn-bûn
@nan
1993 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1993 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1993年の論文
@ja
1993年学术文章
@wuu
1993年学术文章
@zh-cn
1993年学术文章
@zh-hans
1993年学术文章
@zh-my
1993年学术文章
@zh-sg
1993年學術文章
@yue
name
Purification, characterization ...... e-dependent potassium channels
@ast
Purification, characterization ...... e-dependent potassium channels
@en
Purification, characterization ...... e-dependent potassium channels
@nl
type
label
Purification, characterization ...... e-dependent potassium channels
@ast
Purification, characterization ...... e-dependent potassium channels
@en
Purification, characterization ...... e-dependent potassium channels
@nl
prefLabel
Purification, characterization ...... e-dependent potassium channels
@ast
Purification, characterization ...... e-dependent potassium channels
@en
Purification, characterization ...... e-dependent potassium channels
@nl
P2093
P1476
Purification, characterization ...... e-dependent potassium channels
@en
P2093
G J Kaczorowski
M Garcia-Calvo
M L Garcia
R J Leonard
S P Stevens
W Schmalhofer
P304
P407
P577
1993-09-05T00:00:00Z