A divergence in the MAP kinase regulatory network defined by MEK kinase and Raf
about
JNKK1 organizes a MAP kinase module through specific and sequential interactions with upstream and downstream components mediated by its amino-terminal extensionA novel human STE20-related protein kinase, HGK, that specifically activates the c-Jun N-terminal kinase signaling pathwayJSAP1, a novel jun N-terminal protein kinase (JNK)-binding protein that functions as a Scaffold factor in the JNK signaling pathwayHuman JIK, a novel member of the STE20 kinase family that inhibits JNK and is negatively regulated by epidermal growth factorDirect activation of mitogen-activated protein kinase kinase kinase MEKK1 by the Ste20p homologue GCK and the adapter protein TRAF2.Scaffold role of a mitogen-activated protein kinase phosphatase, SKRP1, for the JNK signaling pathwayAcetylcholine muscarinic m1 receptor regulation of cyclic AMP synthesis controls growth factor stimulation of Raf activityRegulation of mitogen-activated protein kinases by a calcium/calmodulin-dependent protein kinase cascadeA human homolog of the yeast Ssk2/Ssk22 MAP kinase kinase kinases, MTK1, mediates stress-induced activation of the p38 and JNK pathwaysDirect activation of the stress-activated protein kinase (SAPK) and extracellular signal-regulated protein kinase (ERK) pathways by an inducible mitogen-activated protein Kinase/ERK kinase kinase 3 (MEKK) derivativeActivation of a human Ste20-like kinase by oxidant stress defines a novel stress response pathway.Regulation of Raf-1 kinase activity by the 14-3-3 family of proteinsMolecular cloning and functional expression of a cDNA encoding a new member of mixed lineage protein kinase from human brainCloning and characterization of a human STE20-like protein kinase with unusual cofactor requirementsInduction and down-regulation of PLK, a human serine/threonine kinase expressed in proliferating cells and tumorsActivation of the c-Jun N-terminal kinase pathway by a novel protein kinase related to human germinal center kinaseCharacterization of the structure and function of a novel MAP kinase kinase (MKK6)Cloning and characterization of a human protein kinase with homology to Ste20Coordinate regulation of IkappaB kinases by mitogen-activated protein kinase kinase kinase 1 and NF-kappaB-inducing kinaseHuman mitogen-activated protein kinase kinase kinase mediates the stress-induced activation of mitogen-activated protein kinase cascadesMip1, an MEKK2-interacting protein, controls MEKK2 dimerization and activation.BMK1/ERK5 regulates serum-induced early gene expression through transcription factor MEF2CThe MAP kinase ERK2 inhibits the cyclic AMP-specific phosphodiesterase HSPDE4D3 by phosphorylating it at Ser579.Interferon-gamma-dependent tyrosine phosphorylation of MEKK4 via Pyk2 is regulated by annexin II and SHP2 in keratinocytesMultiple ras downstream pathways mediate functional repression of the homeobox gene product TTF-1Synergistic interaction of MEK kinase 2, c-Jun N-terminal kinase (JNK) kinase 2, and JNK1 results in efficient and specific JNK1 activationPurification and cDNA cloning of SAPKK3, the major activator of RK/p38 in stress- and cytokine-stimulated monocytes and epithelial cellsActivation of MEK-1 and SEK-1 by Tpl-2 proto-oncoprotein, a novel MAP kinase kinase kinaseActivation of ternary complex factor Elk-1 by MAP kinasesProtein kinase A antagonizes platelet-derived growth factor-induced signaling by mitogen-activated protein kinase in human arterial smooth muscle cellsComparative analysis of the ternary complex factors Elk-1, SAP-1a and SAP-2 (ERP/NET)Identification of the sites in MAP kinase kinase-1 phosphorylated by p74raf-1Mapping of sites on the Src family protein tyrosine kinases p55blk, p59fyn, and p56lyn which interact with the effector molecules phospholipase C-gamma 2, microtubule-associated protein kinase, GTPase-activating protein, and phosphatidylinositol 3-kIdentification and characterization of a new mammalian mitogen-activated protein kinase kinase, MKK2.Signaling by proinflammatory cytokines: oligomerization of TRAF2 and TRAF6 is sufficient for JNK and IKK activation and target gene induction via an amino-terminal effector domainRAS and RAF-1 form a signalling complex with MEK-1 but not MEK-2.Interaction of activated Ras with Raf-1 alone may be sufficient for transformation of rat2 cellsRheb interacts with Raf-1 kinase and may function to integrate growth factor- and protein kinase A-dependent signals.3pK, a novel mitogen-activated protein (MAP) kinase-activated protein kinase, is targeted by three MAP kinase pathwaysInduction of cyclin D1 by simian virus 40 small tumor antigen
P2860
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P2860
A divergence in the MAP kinase regulatory network defined by MEK kinase and Raf
description
1993 nî lūn-bûn
@nan
1993 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1993 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1993年の論文
@ja
1993年学术文章
@wuu
1993年学术文章
@zh-cn
1993年学术文章
@zh-hans
1993年学术文章
@zh-my
1993年学术文章
@zh-sg
1993年學術文章
@yue
name
A divergence in the MAP kinase regulatory network defined by MEK kinase and Raf
@ast
A divergence in the MAP kinase regulatory network defined by MEK kinase and Raf
@en
A divergence in the MAP kinase regulatory network defined by MEK kinase and Raf
@nl
type
label
A divergence in the MAP kinase regulatory network defined by MEK kinase and Raf
@ast
A divergence in the MAP kinase regulatory network defined by MEK kinase and Raf
@en
A divergence in the MAP kinase regulatory network defined by MEK kinase and Raf
@nl
prefLabel
A divergence in the MAP kinase regulatory network defined by MEK kinase and Raf
@ast
A divergence in the MAP kinase regulatory network defined by MEK kinase and Raf
@en
A divergence in the MAP kinase regulatory network defined by MEK kinase and Raf
@nl
P2093
P2860
P356
P1433
P1476
A divergence in the MAP kinase regulatory network defined by MEK kinase and Raf
@en
P2093
A M Gardner
C A Lange-Carter
C M Pleiman
G L Johnson
K J Blumer
P2860
P356
10.1126/SCIENCE.8385802
P407
P577
1993-04-16T00:00:00Z