A high-content chemical screen identifies ellipticine as a modulator of p53 nuclear localization
about
Improved assays for determining the cytosolic access of peptides, proteins, and their mimetics.Characterization and optimization of a novel protein-protein interaction biosensor high-content screening assay to identify disruptors of the interactions between p53 and hDM2.Targeting p53 for Novel Anticancer Therapy.Study of DNA-ellipticine interaction by capillary electrophoresis with laser-induced fluorescence detection.Targeting nucleocytoplasmic transport in cancer therapySuppression of cancer progression by MGAT1 shRNA knockdown.The anticancer drug ellipticine activated with cytochrome P450 mediates DNA damage determining its pharmacological efficiencies: studies with rats, Hepatic Cytochrome P450 Reductase Null (HRN™) mice and pure enzymes.Non-genotoxic anti-neoplastic effects of ellipticine derivative NSC176327 in p53-deficient human colon carcinoma cells involve stimulation of p73The MDM2-p53 pathway revisitedMoving to the core: spatiotemporal analysis of Forkhead box O (FOXO) and nuclear factor-κB (NF-κB) nuclear translocation.Oncoapoptotic markers in oral cancer: prognostics and therapeutic perspective.Regulation of ribosomal gene expression in cancer.The collective nuclear migration of p53 and phosphorylated S473 of Akt during ellipticine-mediated apoptosis in human lung epithelial cancer cells.Assessment of CA1 injury after global ischemia using supervised 2D analyses of nuclear pyknosis.Stimulation of suicidal erythrocyte death by ellipticine.Defining external factors that determine neuronal survival, apoptosis and necrosis during excitotoxic injury using a high content screening imaging platform.Overview of high-throughput screening.Isolation, biological activity and synthesis of the natural product ellipticine and related pyridocarbazoles
P2860
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P2860
A high-content chemical screen identifies ellipticine as a modulator of p53 nuclear localization
description
2008 nî lūn-bûn
@nan
2008 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի մարտին հրատարակված գիտական հոդված
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2008年の論文
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2008年学术文章
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2008年学术文章
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2008年学术文章
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2008年学术文章
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2008年学术文章
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2008年學術文章
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name
A high-content chemical screen ...... or of p53 nuclear localization
@ast
A high-content chemical screen ...... or of p53 nuclear localization
@en
A high-content chemical screen ...... or of p53 nuclear localization
@nl
type
label
A high-content chemical screen ...... or of p53 nuclear localization
@ast
A high-content chemical screen ...... or of p53 nuclear localization
@en
A high-content chemical screen ...... or of p53 nuclear localization
@nl
prefLabel
A high-content chemical screen ...... or of p53 nuclear localization
@ast
A high-content chemical screen ...... or of p53 nuclear localization
@en
A high-content chemical screen ...... or of p53 nuclear localization
@nl
P2093
P2860
P1433
P1476
A high-content chemical screen ...... or of p53 nuclear localization
@en
P2093
C Anne Koch
Chloe J Macrae
Imtiaz A Mawji
James W Dennis
Jeffrey L Wrana
P2860
P2888
P304
P356
10.1007/S10495-007-0175-4
P407
P577
2008-03-01T00:00:00Z