A comparison of the properties of two classes, C4A and C4B, of the human complement component C4
about
Substitution of a single amino acid (aspartic acid for histidine) converts the functional activity of human complement C4B to C4AStructural basis of the polymorphism of human complement components C4A and C4B: gene size, reactivity and antigenicity.The molecular biology, biochemistry, and physiology of human steroidogenesis and its disordersReal-time PCR quantification of human complement C4A and C4B genes.Early Components of the Complement Classical Activation Pathway in Human Systemic Autoimmune DiseasesCovalent binding properties of the human complement protein C4 and hydrolysis rate of the internal thioester upon activationSchizophrenia risk from complex variation of complement component 4The internal thioester and the covalent binding properties of the complement proteins C3 and C4Effect of thiol compounds on human complement component C4Infectious diseases associated with complement deficiencies.Sulfation of tyrosine residues increases activity of the fourth component of complement.Deficiencies of human complement component C4A and C4B and heterozygosity in length variants of RP-C4-CYP21-TNX (RCCX) modules in caucasians. The load of RCCX genetic diversity on major histocompatibility complex-associated disease.Dating the primigenial C4-CYP21 duplication in primates.Polymorphism of the human complement C4 and steroid 21-hydroxylase genes. Restriction fragment length polymorphisms revealing structural deletions, homoduplications, and size variants.Complement and systemic lupus erythematosus.Total C4B deficiency due to gene deletion and gene conversion in a patient with severe infections.A unique recombination event resulting in a C4A*Q0,C4B*Q0 double null haplotype.Gene copy-number variation and associated polymorphisms of complement component C4 in human systemic lupus erythematosus (SLE): low copy number is a risk factor for and high copy number is a protective factor against SLE susceptibility in European AGenetically determined partial complement C4 deficiency states are not independent risk factors for SLE in UK and Spanish populations.Induction of contact sensitivity by cell-associated immunocomplexes requires activation of the early complement componentsStructural differences between the two human complement C4 isotypes affect the humoral immune response.Complement activation and cardiac surgery: a novel target for improving outcomes.Complement-dependent transport of antigen into B cell follicles.Membrane-bound C4b interacts endogenously with complement receptor CR1 of human red cells.Assessment of complement C4 gene copy number using the paralog ratio test.The interaction between complement component C4b-binding protein and the vitamin K-dependent protein S forms a link between blood coagulation and the complement systemIncreased frequency of complement C4B deficiency in rheumatoid arthritisPhenotypes, genotypes and disease susceptibility associated with gene copy number variations: complement C4 CNVs in European American healthy subjects and those with systemic lupus erythematosus.Slp is an essential component of an EDTA-resistant activation pathway of mouse complement.The search for lupus biomarkers.Identification of the 5'-flanking regulatory region responsible for the difference in transcriptional control between mouse complement C4 and Slp genes.Association between C4, C4A, and C4B copy number variations and susceptibility to autoimmune diseases: a meta-analysis.The structure and function of thioester-containing proteins in arthropods.Counterregulatory effects of interferon-gamma and endotoxin on expression of the human C4 genes.Defective prevention of immune precipitation in autoimmune diseases is independent of C4A*Q0.Gene copy-number variations (CNVs) of complement C4 and C4A deficiency in genetic risk and pathogenesis of juvenile dermatomyositis.Influence of C4 null alleles on C4 activation in systemic lupus erythematosus.C4B gene influences intestinal microbiota through complement activation in patients with paediatric-onset inflammatory bowel disease.The origin of the very variable haemolytic activities of the common human complement component C4 allotypes including C4-A6.The complement component C4 of mammals.
P2860
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P2860
A comparison of the properties of two classes, C4A and C4B, of the human complement component C4
description
1984 nî lūn-bûn
@nan
1984 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1984 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1984年の論文
@ja
1984年論文
@yue
1984年論文
@zh-hant
1984年論文
@zh-hk
1984年論文
@zh-mo
1984年論文
@zh-tw
1984年论文
@wuu
name
A comparison of the properties ...... human complement component C4
@ast
A comparison of the properties ...... human complement component C4
@en
A comparison of the properties ...... human complement component C4
@nl
type
label
A comparison of the properties ...... human complement component C4
@ast
A comparison of the properties ...... human complement component C4
@en
A comparison of the properties ...... human complement component C4
@nl
prefLabel
A comparison of the properties ...... human complement component C4
@ast
A comparison of the properties ...... human complement component C4
@en
A comparison of the properties ...... human complement component C4
@nl
P2860
P1433
P1476
A comparison of the properties ...... human complement component C4
@en
P2093
P2860
P304
P356
10.1002/J.1460-2075.1984.TB02052.X
P407
P50
P577
1984-08-01T00:00:00Z