Insulin-dependent translocation of ARNO to the plasma membrane of adipocytes requires phosphatidylinositol 3-kinase
about
ASAP1, a phospholipid-dependent arf GTPase-activating protein that associates with and is phosphorylated by Src.Identification of centaurin-alpha1 as a potential in vivo phosphatidylinositol 3,4,5-trisphosphate-binding protein that is functionally homologous to the yeast ADP-ribosylation factor (ARF) GTPase-activating protein, Gcs1Conformation, localization, and integrin binding of talin depend on its interaction with phosphoinositidesAttenuation of cell adhesion in lymphocytes is regulated by CYTIP, a protein which mediates signal complex sequestrationThe TBC (Tre-2/Bub2/Cdc16) domain protein TRE17 regulates plasma membrane-endosomal trafficking through activation of Arf6.Nerve growth factor- and epidermal growth factor-stimulated translocation of the ADP-ribosylation factor-exchange factor GRP1 to the plasma membrane of PC12 cells requires activation of phosphatidylinositol 3-kinase and the GRP1 pleckstrin homologyStructural basis for membrane recruitment and allosteric activation of cytohesin family Arf GTPase exchange factorsSignal-dependent membrane targeting by pleckstrin homology (PH) domainsMembrane recruitment of DOCK180 by binding to PtdIns(3,4,5)P3Identification and analysis of PH domain-containing targets of phosphatidylinositol 3-kinase using a novel in vivo assay in yeast.The Phox homology (PX) domain, a new player in phosphoinositide signallingThe Gab1 PH domain is required for localization of Gab1 at sites of cell-cell contact and epithelial morphogenesis downstream from the met receptor tyrosine kinaseLocalization of phosphatidylinositol 3-phosphate in yeast and mammalian cellsThe guanine nucleotide exchange factor ARNO mediates the activation of ARF and phospholipase D by insulin.Phosphoinositides: tiny lipids with giant impact on cell regulationA phosphatidylinositol-3-kinase-dependent signal transition regulates ARF1 and ARF6 during Fcgamma receptor-mediated phagocytosisStructural Basis and Mechanism of Autoregulation in 3-Phosphoinositide-Dependent Grp1 Family Arf GTPase Exchange FactorsPhosphatidylinositol 3-kinase-dependent membrane association of the Bruton's tyrosine kinase pleckstrin homology domain visualized in single living cellsRho GTPase control of protein kinase C-related protein kinase activation by 3-phosphoinositide-dependent protein kinaseInteraction of GRASP, a protein encoded by a novel retinoic acid-induced gene, with members of the cytohesin family of guanine nucleotide exchange factorsThe N-terminal coiled coil domain of the cytohesin/ARNO family of guanine nucleotide exchange factors interacts with the scaffolding protein CASPLL5beta is a phosphatidylinositol (3,4,5)-trisphosphate sensor that can bind the cytoskeletal adaptor, gamma-filaminDirect interaction between the cytoplasmic tail of ADAM 12 and the Src homology 3 domain of p85alpha activates phosphatidylinositol 3-kinase in C2C12 cellsThe phox homology (PX) domain-dependent, 3-phosphoinositide-mediated association of sorting nexin-1 with an early sorting endosomal compartment is required for its ability to regulate epidermal growth factor receptor degradationADP-ribosylation factor 6 as a target of guanine nucleotide exchange factor GRP1Cloning and characterization of a 72-kDa inositol-polyphosphate 5-phosphatase localized to the Golgi networkStructural determinants of phosphoinositide selectivity in splice variants of Grp1 family PH domainsIn vivo dynamics of the F-actin-binding protein neurabin-IIInteraction protein for cytohesin exchange factors 1 (IPCEF1) binds cytohesin 2 and modifies its activityPhosphoinositide-dependent activation of the ADP-ribosylation factor GTPase-activating protein ASAP1. Evidence for the pleckstrin homology domain functioning as an allosteric siteSignaling complexes of the FERM domain-containing protein GRSP1 bound to ARF exchange factor GRP1A novel positive feedback loop mediated by the docking protein Gab1 and phosphatidylinositol 3-kinase in epidermal growth factor receptor signalingActivation of ARF6 by ARNO stimulates epithelial cell migration through downstream activation of both Rac1 and phospholipase DGRASP and IPCEF promote ARF-to-Rac signaling and cell migration by coordinating the association of ARNO/cytohesin 2 with Dock180.ARL4D recruits cytohesin-2/ARNO to modulate actin remodelingJFC1, a novel tandem C2 domain-containing protein associated with the leukocyte NADPH oxidase.Desensitization of the luteinizing hormone/choriogonadotropin receptor in ovarian follicular membranes is inhibited by catalytically inactive ARNO(+).Spatial compartmentalization of signal transduction in insulin action.The role of G proteins in insulin signalling.Modular PH and C2 domains in membrane attachment and other functions.
P2860
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P2860
Insulin-dependent translocation of ARNO to the plasma membrane of adipocytes requires phosphatidylinositol 3-kinase
description
1998 nî lūn-bûn
@nan
1998 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Insulin-dependent translocatio ...... phosphatidylinositol 3-kinase
@ast
Insulin-dependent translocatio ...... phosphatidylinositol 3-kinase
@en
Insulin-dependent translocatio ...... phosphatidylinositol 3-kinase
@nl
type
label
Insulin-dependent translocatio ...... phosphatidylinositol 3-kinase
@ast
Insulin-dependent translocatio ...... phosphatidylinositol 3-kinase
@en
Insulin-dependent translocatio ...... phosphatidylinositol 3-kinase
@nl
prefLabel
Insulin-dependent translocatio ...... phosphatidylinositol 3-kinase
@ast
Insulin-dependent translocatio ...... phosphatidylinositol 3-kinase
@en
Insulin-dependent translocatio ...... phosphatidylinositol 3-kinase
@nl
P2093
P1433
P1476
Insulin-dependent translocatio ...... phosphatidylinositol 3-kinase
@en
P2093
J M Tavaré
K Venkateswarlu
P J Cullen
P356
10.1016/S0960-9822(98)70181-2
P407
P577
1998-04-09T00:00:00Z