SynGAP isoforms exert opposing effects on synaptic strength
about
Pathogenic SYNGAP1 mutations impair cognitive development by disrupting maturation of dendritic spine synapses.SYNGAP1: Mind the GapRapid dispersion of SynGAP from synaptic spines triggers AMPA receptor insertion and spine enlargement during LTP.PDZ affinity chromatography: a general method for affinity purification of proteins based on PDZ domains and their ligands.Camkii-mediated phosphorylation regulates distributions of Syngap-α1 and -α2 at the postsynaptic density.SynGAP regulates protein synthesis and homeostatic synaptic plasticity in developing cortical networks.Characterisation of CDKL5 Transcript Isoforms in Human and MouseConvergence of Hippocampal Pathophysiology in Syngap+/- and Fmr1-/y Mice.SYNGAP1 links the maturation rate of excitatory synapses to the duration of critical-period synaptic plasticity.A model for regulation by SynGAP-α1 of binding of synaptic proteins to PDZ-domain 'Slots' in the postsynaptic densityConvergent synaptic and circuit substrates underlying autism genetic risks.Genetic and neurodevelopmental spectrum of SYNGAP1-associated intellectual disability and epilepsy.Interplay of enzymatic and structural functions of CaMKII in long-term potentiation.Wnt-related SynGAP1 is a neuroprotective factor of glutamatergic synapses against Aβ oligomers.Biochemistry and neuroscience: the twain need to meet.Dab2IP Regulates Neuronal Positioning, Rap1 Activity and Integrin Signaling in the Developing CortexAn Antagomir to MicroRNA-106b-5p Ameliorates Cerebral Ischemia and Reperfusion Injury in Rats Via Inhibiting Apoptosis and Oxidative Stress.Alternative promoter usage generates novel shorter MAPT mRNA transcripts in Alzheimer's disease and progressive supranuclear palsy brains.Anchoring high concentrations of SynGAP at postsynaptic densities via liquid-liquid phase separation.Species-conserved SYNGAP1 phenotypes associated with neurodevelopmental disorders.
P2860
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P2860
SynGAP isoforms exert opposing effects on synaptic strength
description
2012 nî lūn-bûn
@nan
2012 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
SynGAP isoforms exert opposing effects on synaptic strength
@ast
SynGAP isoforms exert opposing effects on synaptic strength
@en
SynGAP isoforms exert opposing effects on synaptic strength
@nl
type
label
SynGAP isoforms exert opposing effects on synaptic strength
@ast
SynGAP isoforms exert opposing effects on synaptic strength
@en
SynGAP isoforms exert opposing effects on synaptic strength
@nl
prefLabel
SynGAP isoforms exert opposing effects on synaptic strength
@ast
SynGAP isoforms exert opposing effects on synaptic strength
@en
SynGAP isoforms exert opposing effects on synaptic strength
@nl
P2093
P2860
P50
P3181
P356
P1476
SynGAP isoforms exert opposing effects on synaptic strength
@en
P2093
M O Collins
M W Barnett
N H Komiyama
P N Stoney
P2860
P2888
P3181
P356
10.1038/NCOMMS1900
P407
P50
P577
2012-06-12T00:00:00Z
P5875
P6179
1025012362