The C terminus of cardiac troponin I stabilizes the Ca2+-activated state of tropomyosin on actin filaments
about
Gene regulation, alternative splicing, and posttranslational modification of troponin subunits in cardiac development and adaptation: a focused reviewCalcium-regulated conformational change in the C-terminal end segment of troponin I and its binding to tropomyosinStructural basis for the in situ Ca(2+) sensitization of cardiac troponin C by positive feedback from force-generating myosin cross-bridgesThin filament mutations: developing an integrative approach to a complex disorderThe cardiac acetyl-lysine proteomeA novel phosphorylation site, Serine 199, in the C-terminus of cardiac troponin I regulates calcium sensitivity and susceptibility to calpain-induced proteolysisTNNI1, TNNI2 and TNNI3: Evolution, regulation, and protein structure-function relationships.A model of calcium activation of the cardiac thin filamentCitrullination of myofilament proteins in heart failure.Dual regulatory functions of the thin filament revealed by replacement of the troponin I inhibitory peptide with a linkerLow temperature dynamic mapping reveals unexpected order and disorder in troponin.Structural dynamics of C-domain of cardiac troponin I protein in reconstituted thin filamentNitroxyl-mediated disulfide bond formation between cardiac myofilament cysteines enhances contractile function.Conformation and Dynamics of the Troponin I C-Terminal Domain: Combining Single-Molecule and Computational Approaches for a Disordered Protein Region.Significance of troponin dynamics for Ca2+-mediated regulation of contraction and inherited cardiomyopathy.Molecular effects of familial hypertrophic cardiomyopathy-related mutations in the TNT1 domain of cTnT.Structural and kinetic effects of hypertrophic cardiomyopathy related mutations R146G/Q and R163W on the regulatory switching activity of rat cardiac troponin IAtomic resolution probe for allostery in the regulatory thin filament.Role of cardiac troponin I carboxy terminal mobile domain and linker sequence in regulating cardiac contraction.The functional significance of the last 5 residues of the C-terminus of cardiac troponin I.Effect of N-Terminal Extension of Cardiac Troponin I on the Ca(2+) Regulation of ATP Binding and ADP Dissociation of Myosin II in Native Cardiac Myofibrils.Biochemical characterisation of Troponin C mutations causing hypertrophic and dilated cardiomyopathies.The functional diversity of essential genes required for mammalian cardiac development.Order-Disorder Transitions in the Cardiac Troponin Complex.The Relaxation Properties of Myofibrils Are Compromised by Amino Acids that Stabilize α-Tropomyosin.Restrictive Cardiomyopathy Caused by Troponin Mutations: Application of Disease Animal Models in Translational StudiesGreen Tea Catechin Normalizes the Enhanced Ca2+ Sensitivity of Myofilaments Regulated by a Hypertrophic Cardiomyopathy-Associated Mutation in Human Cardiac Troponin I (K206I)Structural implications of conserved aspartate residues located in tropomyosin's coiled-coil core.Functional significance of C-terminal mobile domain of cardiac troponin I.Heart Failure-Related Hyperphosphorylation in the Cardiac Troponin I C Terminus Has Divergent Effects on Cardiac Function In Vivo.The continuing evolution of cardiac troponin I biomarker analysis: from protein to proteoform.Role of the C-terminus mobile domain of cardiac troponin I in the regulation of thin filament activation in skinned papillary muscle strips.
P2860
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P2860
The C terminus of cardiac troponin I stabilizes the Ca2+-activated state of tropomyosin on actin filaments
description
2010 nî lūn-bûn
@nan
2010 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի մարտին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
The C terminus of cardiac trop ...... tropomyosin on actin filaments
@ast
The C terminus of cardiac trop ...... tropomyosin on actin filaments
@en
The C terminus of cardiac trop ...... tropomyosin on actin filaments
@nl
type
label
The C terminus of cardiac trop ...... tropomyosin on actin filaments
@ast
The C terminus of cardiac trop ...... tropomyosin on actin filaments
@en
The C terminus of cardiac trop ...... tropomyosin on actin filaments
@nl
prefLabel
The C terminus of cardiac trop ...... tropomyosin on actin filaments
@ast
The C terminus of cardiac trop ...... tropomyosin on actin filaments
@en
The C terminus of cardiac trop ...... tropomyosin on actin filaments
@nl
P2093
P2860
P1433
P1476
The C terminus of cardiac trop ...... tropomyosin on actin filaments
@en
P2093
Agnieszka Galińska
Anne M Murphy
C-L Albert Wang
Jennifer E Van Eyk
Roger Craig
Victoria Hatch
P2860
P304
P356
10.1161/CIRCRESAHA.109.210047
P407
P577
2009-12-24T00:00:00Z