Downstream processing of monoclonal antibodies--application of platform approaches
about
Industrialization of mAb production technology: the bioprocessing industry at a crossroadsRecovery and purification process development for monoclonal antibody productionHigh-Capacity Hierarchically Imprinted Polymer Beads for Protein Recognition and CaptureNature of foulants and fouling mechanism in the Protein A MabSelect resin cycled in a monoclonal antibody purification process.Structural and functional characteristics of virgin and fouled Protein A MabSelect resin cycled in a monoclonal antibody purification process.Predictive approach for protein aggregation: Correlation of protein surface characteristics and conformational flexibility to protein aggregation propensity.Aggregation Kinetics for IgG1-Based Monoclonal Antibody Therapeutics.Hitchhiker antigens: inconsistent ChIP results, questionable immunohistology data, and poor antibody performance may have a common factor.Advances in inline quantification of co-eluting proteins in chromatography: Process-data-based model calibration and application towards real-life separation issues.High-throughput profiling of N-linked oligosaccharides in therapeutic antibodies using a microfluidic CD platform and MALDI-MS.High-mannose glycans on the Fc region of therapeutic IgG antibodies increase serum clearance in humans.Cation-exchange chromatography of monoclonal antibodies: characterisation of a novel stationary phase designed for production-scale purificationNeutron reflectivity measurement of protein A-antibody complex at the solid-liquid interface.A non-chromatographic method for the purification of a bivalently active monoclonal IgG antibody from biological fluidsEvaluation of protein engineering and process optimization approaches to enhance antibody drug manufacturability.Engineered protein A ligands, derived from a histidine-scanning library, facilitate the affinity purification of IgG under mild acidic conditions.Porcine parvovirus removal using trimer and biased hexamer peptides.Host cell protein dynamics in the supernatant of a mAb producing CHO cell line.Porcine circovirus (PCV) removal by Q sepharose fast flow chromatographyProtected hinge in the immunoglobulin G2-A2 disulfide isoformImpact of glycation on antibody clearanceAnalyzing clonal variation of monoclonal antibody-producing CHO cell lines using an in silico metabolomic platformHuman IgG2 antibodies display disulfide-mediated structural isoforms.High-throughput strategies for the discovery and engineering of enzymes for biocatalysis.Flow Cytometry as a Tool for Quality Control of Fluorescent Conjugates Used in ImmunoassaysQSAR models for prediction of chromatographic behavior of homologous Fab variants.Cost-effective production of a vaginal protein microbicide to prevent HIV transmission.Acid-induced aggregation propensity of nivolumab is dependent on the Fc.Human IgG1 hinge fragmentation as the result of H2O2-mediated radical cleavage.Human antibodies targeting the C-type lectin-like domain of the tumor endothelial cell marker clec14a regulate angiogenic properties in vitro.Aggregates in monoclonal antibody manufacturing processes.State-of-the-art in downstream processing of monoclonal antibodies: process trends in design and validation.Protein production using the baculovirus-insect cell expression system.Host cell protein testing by ELISAs and the use of orthogonal methods.Accelerated formulation development of monoclonal antibodies (mAbs) and mAb-based modalities: review of methods and tools.The present state of the art in expression, production and characterization of monoclonal antibodies.Clarification technologies for monoclonal antibody manufacturing processes: Current state and future perspectives.Downstream Processing Technologies/Capturing and Final Purification : Opportunities for Innovation, Change, and Improvement. A Review of Downstream Processing Developments in Protein Purification.Sophisticated Cloning, Fermentation, and Purification Technologies for an Enhanced Therapeutic Protein Production: A Review.Maximizing the functional lifetime of Protein A resins.
P2860
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P2860
Downstream processing of monoclonal antibodies--application of platform approaches
description
2007 nî lūn-bûn
@nan
2007 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի մարտին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Downstream processing of monoclonal antibodies--application of platform approaches
@ast
Downstream processing of monoclonal antibodies--application of platform approaches
@en
Downstream processing of monoclonal antibodies--application of platform approaches
@nl
type
label
Downstream processing of monoclonal antibodies--application of platform approaches
@ast
Downstream processing of monoclonal antibodies--application of platform approaches
@en
Downstream processing of monoclonal antibodies--application of platform approaches
@nl
prefLabel
Downstream processing of monoclonal antibodies--application of platform approaches
@ast
Downstream processing of monoclonal antibodies--application of platform approaches
@en
Downstream processing of monoclonal antibodies--application of platform approaches
@nl
P2093
P3181
P1476
Downstream processing of monoclonal antibodies--application of platform approaches
@en
P2093
Abhinav A Shukla
Brian Hubbard
Duncan Low
Tim Tressel
P3181
P356
10.1016/J.JCHROMB.2006.09.026
P407
P577
2007-03-15T00:00:00Z