FANCM connects the genome instability disorders Bloom's Syndrome and Fanconi Anemia
about
CtIP is required to initiate replication-dependent interstrand crosslink repairScaffolding protein SPIDR/KIAA0146 connects the Bloom syndrome helicase with homologous recombination repairDNA repair. Proteomics reveals dynamic assembly of repair complexes during bypass of DNA cross-linksInteraction between the helicases genetically linked to Fanconi anemia group J and Bloom's syndromeIdentification of KIAA1018/FAN1, a DNA repair nuclease recruited to DNA damage by monoubiquitinated FANCD2Molecular pathogenesis and clinical management of Fanconi anemiaSusceptibility pathways in Fanconi's anemia and breast cancerIron Homeostasis in Health and DiseaseUpdate of the human and mouse Fanconi anemia genesFunctions and regulation of the multitasking FANCM family of DNA motor proteinsExploiting the Fanconi Anemia Pathway for Targeted Anti-Cancer TherapyRoles of DNA helicases in the maintenance of genome integrityStructure and Cellular Roles of the RMI Core Complex from the Bloom Syndrome DissolvasomeDefining the molecular interface that connects the Fanconi anemia protein FANCM to the Bloom syndrome dissolvasomeThe structure of the FANCM–MHF complex reveals physical features for functional assemblyArchitecture and DNA Recognition Elements of the Fanconi Anemia FANCM-FAAP24 ComplexStructural insights into the functions of the FANCM-FAAP24 complex in DNA repairThe DNA Damage Response: Making It Safe to Play with KnivesMutations in ERCC4, encoding the DNA-repair endonuclease XPF, cause Fanconi anemiaAdvances in understanding the complex mechanisms of DNA interstrand cross-link repairLoss of RMI2 Increases Genome Instability and Causes a Bloom-Like SyndromeExpanded roles of the Fanconi anemia pathway in preserving genomic stabilityCytokinesis failure occurs in Fanconi anemia pathway-deficient murine and human bone marrow hematopoietic cellsMultiple interactions of the intrinsically disordered region between the helicase and nuclease domains of the archaeal Hef proteinMechanistic and biological aspects of helicase action on damaged DNA.The FANCM/FAAP24 complex is required for the DNA interstrand crosslink-induced checkpoint responseThe genetic and biochemical basis of FANCD2 monoubiquitinationThe Rothmund-Thomson syndrome helicase RECQL4 is essential for hematopoiesis.KIAA1018/FAN1 nuclease protects cells against genomic instability induced by interstrand cross-linking agents.Essential functions of iron-requiring proteins in DNA replication, repair and cell cycle control.MHF1 plays Fanconi anaemia complementation group M protein (FANCM)-dependent and FANCM-independent roles in DNA repair and homologous recombination in plants.Heterozygous mutations in DNA repair genes and hereditary breast cancer: a question of power.The dissolution of double Holliday junctions.FANCB is essential in the male germline and regulates H3K9 methylation on the sex chromosomes during meiosis.Rescue from replication stress during mitosis.Fanconi anemia group J helicase and MRE11 nuclease interact to facilitate the DNA damage response.Role of replication protein A in double holliday junction dissolution mediated by the BLM-Topo IIIα-RMI1-RMI2 protein complexDefective FANCI binding by a fanconi anemia-related FANCD2 mutant.Human FAN1 promotes strand incision in 5'-flapped DNA complexed with RPA.Fanconi anemia and Bloom's syndrome crosstalk through FANCJ-BLM helicase interaction.
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P2860
FANCM connects the genome instability disorders Bloom's Syndrome and Fanconi Anemia
description
2009 nî lūn-bûn
@nan
2009 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
FANCM connects the genome instability disorders Bloom's Syndrome and Fanconi Anemia
@ast
FANCM connects the genome instability disorders Bloom's Syndrome and Fanconi Anemia
@en
FANCM connects the genome instability disorders Bloom's Syndrome and Fanconi Anemia
@nl
type
label
FANCM connects the genome instability disorders Bloom's Syndrome and Fanconi Anemia
@ast
FANCM connects the genome instability disorders Bloom's Syndrome and Fanconi Anemia
@en
FANCM connects the genome instability disorders Bloom's Syndrome and Fanconi Anemia
@nl
prefLabel
FANCM connects the genome instability disorders Bloom's Syndrome and Fanconi Anemia
@ast
FANCM connects the genome instability disorders Bloom's Syndrome and Fanconi Anemia
@en
FANCM connects the genome instability disorders Bloom's Syndrome and Fanconi Anemia
@nl
P3181
P1433
P1476
FANCM connects the genome instability disorders Bloom's Syndrome and Fanconi Anemia
@en
P304
P3181
P356
10.1016/J.MOLCEL.2009.12.006
P407
P577
2009-12-25T00:00:00Z