The IkappaB kinase - a bridge between inflammation and cancer
about
Towards a unifying, systems biology understanding of large-scale cellular death and destruction caused by poorly liganded iron: Parkinson's, Huntington's, Alzheimer's, prions, bactericides, chemical toxicology and others as examplesKappaB-Ras is a nuclear-cytoplasmic small GTPase that inhibits NF-kappaB activation through the suppression of transcriptional activation of p65/RelAEvolution of host innate defence: insights from Caenorhabditis elegans and primitive invertebratesTumor endothelin-1 enhances metastatic colonization of the lung in mouse xenograft models of bladder cancerThe mTOR signalling pathway in human cancerpoky/chuk/ikk1 is required for differentiation of the zebrafish embryonic epidermis.Regulation of glucose metabolism by p53: emerging new roles for the tumor suppressorMolecular and Cellular Effects of Hydrogen Peroxide on Human Lung Cancer Cells: Potential Therapeutic ImplicationsThe SphKs/S1P/S1PR1 axis in immunity and cancer: more ore to be minedTargeting apoptosis pathways in cancer with alantolactone and isoalantolactoneMechanisms of virus immune evasion lead to development from chronic inflammation to cancer formation associated with human papillomavirus infectionIncreased IKKα expression in the basal layer of the epidermis of transgenic mice enhances the malignant potential of skin tumorsInflammation and proliferation act together to mediate intestinal cell fusionDangerous liaisons: STAT3 and NF-kappaB collaboration and crosstalk in cancerGadd45 proteins as critical signal transducers linking NF-kappaB to MAPK cascadesIron behaving badly: inappropriate iron chelation as a major contributor to the aetiology of vascular and other progressive inflammatory and degenerative diseasesGrowth inhibition and apoptosis induced by osthole, a natural coumarin, in hepatocellular carcinomaNF-kappaB in lung cancer, a carcinogenesis mediator and a prevention and therapy targetMechanical phenotype is important for stromal aromatase expression.Loss of TFF1 is associated with activation of NF-κB-mediated inflammation and gastric neoplasia in mice and humansIKKbeta mediates cell shape-induced aromatase expression and estrogen biosynthesis in adipose stromal cellsRNAi-mediated c-Rel silencing leads to apoptosis of B cell tumor cells and suppresses antigenic immune response in vivo.Inflammation and oncogenesis: a vicious connection.Anticancer Role of PPARgamma Agonists in Hematological Malignancies Found in the Vasculature, Marrow, and Eyes.Macrophage Apoptosis and Efferocytosis in the Pathogenesis of AtherosclerosisThe receptor tyrosine kinase FGFR4 negatively regulates NF-kappaB signaling.Loss of glutathione peroxidase 7 promotes TNF-α-induced NF-κB activation in Barrett's carcinogenesis.Tumor-fibroblast interactions stimulate tumor vascularization by enhancing cytokine-driven production of MMP9 by tumor cells.Oxidants positively or negatively regulate nuclear factor kappaB in a context-dependent mannerHave tumor suppressor PDCD4 and its counteragent oncogenic miR-21 gone rogue?Tyrosine phosphorylation is required for IkappaB kinase-beta (IKKbeta) activation and function in osteoclastogenesisInhibition of choriodecidual cytokine production and inflammatory gene expression by selective I-kappaB kinase (IKK) inhibitors.Bacterial flagellin elicits widespread innate immune defense mechanisms, apoptotic signaling, and a sepsis-like systemic inflammatory response in mice.The tumor microenvironment of colorectal cancer: stromal TLR-4 expression as a potential prognostic markerOral feeding of pomegranate fruit extract inhibits early biomarkers of UVB radiation-induced carcinogenesis in SKH-1 hairless mouse epidermisMEKK3 expression correlates with nuclear factor kappa B activity and with expression of antiapoptotic genes in serous ovarian carcinoma.Comparative gene expression profiling identifies common molecular signatures of NF-κB activation in canine and human diffuse large B cell lymphoma (DLBCL).The hypoxia-inducible transcription factor ZNF395 is controlled by IĸB kinase-signaling and activates genes involved in the innate immune response and cancer.Mediators of Tyrosine Phosphorylation in Innate Immunity: From Host Defense to Inflammation onto Oncogenesis.Development of small-molecule inhibitors of sphingosine-1-phosphate signaling
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P2860
The IkappaB kinase - a bridge between inflammation and cancer
description
2008 nî lūn-bûn
@nan
2008 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի մարտին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
The IkappaB kinase - a bridge between inflammation and cancer
@ast
The IkappaB kinase - a bridge between inflammation and cancer
@en
The IkappaB kinase - a bridge between inflammation and cancer
@nl
type
label
The IkappaB kinase - a bridge between inflammation and cancer
@ast
The IkappaB kinase - a bridge between inflammation and cancer
@en
The IkappaB kinase - a bridge between inflammation and cancer
@nl
prefLabel
The IkappaB kinase - a bridge between inflammation and cancer
@ast
The IkappaB kinase - a bridge between inflammation and cancer
@en
The IkappaB kinase - a bridge between inflammation and cancer
@nl
P2860
P3181
P356
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P1476
The IkappaB kinase - a bridge between inflammation and cancer
@en
P2860
P2888
P304
P3181
P356
10.1038/CR.2008.30
P407
P577
2008-03-01T00:00:00Z
P5875
P6179
1022299285