A novel one-armed anti-c-Met antibody inhibits glioblastoma growth in vivo
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Three-dimensional lung tumor microenvironment modulates therapeutic compound responsiveness in vitro--implication for drug developmentThe MET axis as a therapeutic target.Biomarker development in MET-targeted therapyMolecular classification of gastric cancer: Towards a pathway-driven targeted therapyMET inhibitors in combination with other therapies in non-small cell lung cancerTargeting the epithelial to mesenchymal transition in glioblastoma: the emerging role of MET signalingDual anti-idiotypic purification of a novel, native-format biparatopic anti-MET antibody with improved in vitro and in vivo efficacy.c-Met inhibitors with novel binding mode show activity against several hereditary papillary renal cell carcinoma-related mutationsMonovalent antibody design and mechanism of action of onartuzumab, a MET antagonist with anti-tumor activity as a therapeutic agentAn allosteric switch for pro-HGF/Met signaling using zymogen activator peptidesDurable complete response of metastatic gastric cancer with anti-Met therapy followed by resistance at recurrence.A phase II study evaluating the efficacy and safety of AMG 102 (rilotumumab) in patients with recurrent glioblastomaAn orally bioavailable c-Met kinase inhibitor potently inhibits brain tumor malignancy and growth.Transcription-dependent epidermal growth factor receptor activation by hepatocyte growth factor.Four individually druggable MET hotspots mediate HGF-driven tumor progression.Constitutively active c-Met kinase in PC-3 cells is autocrine-independent and can be blocked by the Met kinase inhibitor BMS-777607.Therapeutic strategies for inhibiting invasion in glioblastoma.A novel bispecific c-MET/PD-1 antibody with therapeutic potential in solid cancer.EGFRvIII and c-Met pathway inhibitors synergize against PTEN-null/EGFRvIII+ glioblastoma xenografts.Comprehensive engineering of Escherichia coli for enhanced expression of IgG antibodiesBeyond natural antibodies: the power of in vitro display technologies.A novel decoy receptor fusion protein for FGF-2 potently inhibits tumour growth.In vivo characterization of several rodent glioma models by 1H MRSSmall molecule c-Met kinase inhibitors: a review of recent patents.A novel multipurpose monoclonal antibody for evaluating human c-Met expression in preclinical and clinical settings.New radiotracers for imaging of vascular targets in angiogenesis-related diseases.Non-agonistic bivalent antibodies that promote c-MET degradation and inhibit tumor growth and others specific for tumor related c-MET.Inhibition of the MET Receptor Tyrosine Kinase as a Novel Therapeutic Strategy in MedulloblastomaAnti-MET immunoPET for non-small cell lung cancer using novel fully human antibody fragmentsHGF rescues colorectal cancer cells from EGFR inhibition via MET activationAmiloride-sensitive Na+ channels contribute to regulatory volume increases in human glioma cells.The evolving genomic classification of lung cancer.Molecular alterations in glioblastoma: potential targets for immunotherapy.Randomized phase II trial of Onartuzumab in combination with erlotinib in patients with advanced non-small-cell lung cancer.Receptor-tyrosine-kinase-targeted therapies for head and neck cancer.VEGF and c-Met blockade amplify angiogenesis inhibition in pancreatic islet cancerStrategies for overcoming resistance to EGFR family tyrosine kinase inhibitorsThe role of the c-Met pathway in lung cancer and the potential for targeted therapy.PTEN reconstitution alters glioma responses to c-Met pathway inhibition.The hepatocyte growth factor/c-Met signaling pathway as a therapeutic target to inhibit angiogenesis.
P2860
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P2860
A novel one-armed anti-c-Met antibody inhibits glioblastoma growth in vivo
description
2006 nî lūn-bûn
@nan
2006 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
A novel one-armed anti-c-Met antibody inhibits glioblastoma growth in vivo
@ast
A novel one-armed anti-c-Met antibody inhibits glioblastoma growth in vivo
@en
A novel one-armed anti-c-Met antibody inhibits glioblastoma growth in vivo
@nl
type
label
A novel one-armed anti-c-Met antibody inhibits glioblastoma growth in vivo
@ast
A novel one-armed anti-c-Met antibody inhibits glioblastoma growth in vivo
@en
A novel one-armed anti-c-Met antibody inhibits glioblastoma growth in vivo
@nl
altLabel
A Novel One-Armed Anti-c-Met Antibody Inhibits Glioblastoma Growth In vivo
@en
prefLabel
A novel one-armed anti-c-Met antibody inhibits glioblastoma growth in vivo
@ast
A novel one-armed anti-c-Met antibody inhibits glioblastoma growth in vivo
@en
A novel one-armed anti-c-Met antibody inhibits glioblastoma growth in vivo
@nl
P2093
P3181
P1476
A novel one-armed anti-c-Met antibody inhibits glioblastoma growth in vivo
@en
P2093
Carmen Eckerich
Katrin Lamszus
Manfred Westphal
Nils-Ole Schmidt
Ralph Schwall
Regina Fillbrandt
Tobias Martens
P304
P3181
P356
10.1158/1078-0432.CCR-05-1418
P407
P433
P577
2006-10-01T00:00:00Z