A genome-wide association study identifies IL23R as an inflammatory bowel disease gene - Wikidata - wikimedia - TriplyDB

A genome-wide association study identifies IL23R as an inflammatory bowel disease gene

A genome-wide association study identifies IL23R as an inflammatory bowel disease gene

http://www.wikidata.org/entity/Q28270603

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Systematic association mapping identifies NELL1 as a novel IBD disease gene Intestinal DMBT1 expression is modulated by Crohn's disease-associated IL23R variants and by a DMBT1 variant which influences binding of the transcription factors CREB1 and ATF-2 Evidence for significant overlap between common risk variants for Crohn's disease and ankylosing spondylitis Genetic Association of Peptidoglycan Recognition Protein Variants with Inflammatory Bowel Disease A genome-wide association study of psoriasis and psoriatic arthritis identifies new disease loci Subtype specific genetic associations for juvenile idiopathic arthritis: ERAP1 with the enthesitis related arthritis subtype and IL23R with juvenile psoriatic arthritis Interaction of Crohn's disease susceptibility genes in an Australian paediatric cohort Molecular reclassification of Crohn's disease by cluster analysis of genetic variants Analysis of East Asia genetic substructure using genome-wide SNP arrays Interpretation of genetic association studies: markers with replicated highly significant odds ratios may be poor classifiers Crohn's disease risk alleles on the NOD2 locus have been maintained by natural selection on standing variation Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease Innate immunity in inflammatory bowel disease: a disease hypothesis Involvement of mycobacterium avium subspecies paratuberculosis in TNF-α production from macrophage: Possible link between MAP and immune response in Crohnʼs disease Fine mapping versus replication in whole-genome association studies TGF-beta-induced Foxp3 inhibits T(H)17 cell differentiation by antagonizing RORgammat function Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls Ustekinumab in psoriasis immunopathology with emphasis on the Th17-IL23 axis: a primer The interleukin 23 receptor is essential for the terminal differentiation of interleukin 17-producing effector T helper cells in vivo High prevalence of viable Mycobacterium avium subspecies paratuberculosis in Crohn's disease Deep resequencing of GWAS loci identifies independent rare variants associated with inflammatory bowel disease Characterization of interleukin-17-producing regulatory T cells in inflamed intestinal mucosa from patients with inflammatory bowel diseases Genome-wide association scan for five major dimensions of personality NKX2-3 and IRGM variants are associated with disease susceptibility to IBD in Eastern European patients Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci The emerging role of IL-17 in the pathogenesis of psoriasis: preclinical and clinical findings Genomic views of STAT function in CD4+ T helper cell differentiation A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus Psoriasis genetics: breaking the barrier Association of linear growth impairment in pediatric Crohn's disease and a known height locus: a pilot study Comparative genetic analysis of inflammatory bowel disease and type 1 diabetes implicates multiple loci with opposite effects Primary biliary cirrhosis associated with HLA, IL12A, and IL12RB2 variants Ulcerative colitis-risk loci on chromosomes 1p36 and 12q15 found by genome-wide association study Diverse genome-wide association studies associate the IL12/IL23 pathway with Crohn Disease IL23R variation determines susceptibility but not disease phenotype in inflammatory bowel disease Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants Loci on 20q13 and 21q22 are associated with pediatric-onset inflammatory bowel disease Genome-wide association scan identifies candidate polymorphisms associated with differential response to anti-TNF treatment in rheumatoid arthritis Structure and signalling in the IL-17 receptor family European population genetic substructure: further definition of ancestry informative markers for distinguishing among diverse European ethnic groups

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A genome-wide association study identifies IL23R as an inflammatory bowel disease gene

http://www.wikidata.org/entity/Q28270603

description

2006 nî lūn-bûn

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2006 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2006 թվականի դեկտեմբերին հրատարակված գիտական հոդված

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2006年の論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年论文

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name

A genome-wide association study identifies IL23R as an inflammatory bowel disease gene

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A genome-wide association study identifies IL23R as an inflammatory bowel disease gene

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A genome-wide association study identifies IL23R as an inflammatory bowel disease gene

@nl

type

label

A genome-wide association study identifies IL23R as an inflammatory bowel disease gene

@ast

A genome-wide association study identifies IL23R as an inflammatory bowel disease gene

@en

A genome-wide association study identifies IL23R as an inflammatory bowel disease gene

@nl

prefLabel

A genome-wide association study identifies IL23R as an inflammatory bowel disease gene

@ast

A genome-wide association study identifies IL23R as an inflammatory bowel disease gene

@en

A genome-wide association study identifies IL23R as an inflammatory bowel disease gene

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A genome-wide association study identifies IL23R as an inflammatory bowel disease gene

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Alain Bitton

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Anne Griffiths

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Annette T Lee

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Clara Abraham

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Emily O Kistner

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Judy H Cho

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Kent D Taylor

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L Philip Schumm

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P2860

Inflammatory Bowel Disease

A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease

Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12

A receptor for the heterodimeric cytokine IL-23 is composed of IL-12Rbeta1 and a novel cytokine receptor subunit, IL-23R

Human IL-23-producing type 1 macrophages promote but IL-10-producing type 2 macrophages subvert immunity to (myco)bacteria

Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells

Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease

Ubiquitous transgenic expression of the IL-23 subunit p19 induces multiorgan inflammation, runting, infertility, and premature death

Interleukin-23 promotes a distinct CD4 T cell activation state characterized by the production of interleukin-17

Transforming growth factor-beta induces development of the T(H)17 lineage

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Mark Joseph Daly

Michael Barmada

Jerome I Rotter

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