Reconstitution of hairpin ribozyme activity following separation of functional domains
about
De novo synthesis and development of an RNA enzymeCrystal structure of a hairpin ribozyme-inhibitor complex with implications for catalysisA posterioridesign of crystal contacts to improve the X-ray diffraction properties of a small RNA enzymeStructural basis for heterogeneous kinetics: reengineering the hairpin ribozymeWater in the active site of an all-RNA hairpin ribozyme and effects of Gua8 base variants on the geometry of phosphoryl transferFunctional involvement of G8 in the hairpin ribozyme cleavage mechanism.Imaging of single hairpin ribozymes in solution by atomic force microscopy.Small self-cleaving ribozymesTertiary structure formation in the hairpin ribozyme monitored by fluorescence resonance energy transferCleavage of highly structured viral RNA molecules by combinatorial libraries of hairpin ribozymes. The most effective ribozymes are not predicted by substrate selection rules.Exploring ribozyme conformational changes with X-ray crystallography.Ligation activity of fragmented ribozymes in frozen solution: implications for the RNA world.Mg2+-independent hairpin ribozyme catalysis in hydrated RNA films.Modifications and deletions of helices within the hairpin ribozyme-substrate complex: an active ribozyme lacking helix 1.The loop B domain is physically separable from the loop A domain in the hairpin ribozyme.The hairpin ribozyme.Mutational inhibition of ligation in the hairpin ribozyme: substitutions of conserved nucleobases A9 and A10 destabilize tertiary structure and selectively promote cleavage.Intermolecular domain docking in the hairpin ribozyme: metal dependence, binding kinetics and catalysisCation-specific structural accommodation within a catalytic RNA.Generation of functional RNAs from inactive oligonucleotide complexes by non-enzymatic primer extensionModulating RNA structure and catalysis: lessons from small cleaving ribozymes.The many faces of the hairpin ribozyme: structural and functional variants of a small catalytic RNA.Analysis of the functional role of a G.A sheared base pair by in vitro genetics.An RNA aptamer to the xanthine/guanine base with a distinctive mode of purine recognition.In vitro selection of second site revertants analysis of the hairpin ribozyme active site.Thermodynamics and kinetics of RNA tertiary structure formation in the junctionless hairpin ribozyme.RNA double cleavage by a hairpin-derived twin ribozyme.Base and sugar requirements for RNA cleavage of essential nucleoside residues in internal loop B of the hairpin ribozyme: implications for secondary structure.Metal ions play a passive role in the hairpin ribozyme catalysed reactionFreeze-thaw cycles as drivers of complex ribozyme assembly.The folding of the hairpin ribozyme: dependence on the loops and the junctionThe influence of junction conformation on RNA cleavage by the hairpin ribozyme in its natural junction form.Probing RNA structural dynamics and function by fluorescence resonance energy transfer (FRET).
P2860
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P2860
Reconstitution of hairpin ribozyme activity following separation of functional domains
description
1995 nî lūn-bûn
@nan
1995 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
Reconstitution of hairpin ribozyme activity following separation of functional domains
@ast
Reconstitution of hairpin ribozyme activity following separation of functional domains
@en
Reconstitution of hairpin ribozyme activity following separation of functional domains
@nl
type
label
Reconstitution of hairpin ribozyme activity following separation of functional domains
@ast
Reconstitution of hairpin ribozyme activity following separation of functional domains
@en
Reconstitution of hairpin ribozyme activity following separation of functional domains
@nl
prefLabel
Reconstitution of hairpin ribozyme activity following separation of functional domains
@ast
Reconstitution of hairpin ribozyme activity following separation of functional domains
@en
Reconstitution of hairpin ribozyme activity following separation of functional domains
@nl
P2093
P356
P1476
Reconstitution of hairpin ribozyme activity following separation of functional domains
@en
P2093
J E Heckman
S E Butcher
P304
P356
10.1074/JBC.270.50.29648
P407
P577
1995-12-15T00:00:00Z