Sex- and tissue-specific changes in mTOR signaling with age in C57BL/6J mice - Wikidata - wikimedia - TriplyDB

Sex- and tissue-specific changes in mTOR signaling with age in C57BL/6J mice

Sex- and tissue-specific changes in mTOR signaling with age in C57BL/6J mice

http://www.wikidata.org/entity/Q28271425

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The Mechanistic Target of Rapamycin: The Grand ConducTOR of Metabolism and Aging Increased 4E-BP1 Expression Protects against Diet-Induced Obesity and Insulin Resistance in Male Mice.Moderate lifelong overexpression of tuberous sclerosis complex 1 (TSC1) improves health and survival in mice Aging and Autophagy in the Heart Rapamycin: An InhibiTOR of Aging Emerges From the Soil of Easter Island.Rapamycin increases grip strength and attenuates age-related decline in maximal running distance in old low capacity runner rats.Comparative idiosyncrasies in life extension by reduced mTOR signalling and its distinctiveness from dietary restriction Age related increase in mTOR activity contributes to the pathological changes in ovarian surface epithelium.Voluntary resistance wheel exercise from mid-life prevents sarcopenia and increases markers of mitochondrial function and autophagy in muscles of old male and female C57BL/6J mice.The underlying mechanism of proinflammatory NF-κB activation by the mTORC2/Akt/IKKα pathway during skin aging.Sexual dimorphism in glioma glycolysis underlies sex differences in survival Sex differences in aging: genomic instability.mTOR drives cerebral blood flow and memory deficits in LDLR(-/-) mice modeling atherosclerosis and vascular cognitive impairment.Alcoholic Cardiomyopathy: Disrupted Protein Balance and Impaired Cardiomyocyte Contractility.Life history evolution, reproduction, and the origins of sex-dependent aging and longevity.Evidence that a mitochondrial death spiral underlies antagonistic pleiotropy.Simulation of Cellular Energy Restriction in Quiescence (ERiQ)-A Theoretical Model for Aging.PTEN deletion increases hippocampal granule cell excitability in male and female mice.Restoration of metabolic health by decreased consumption of branched-chain amino acids.Deletion of Nrip1 extends female mice longevity, increases autophagy, and delays cell senescence.Evolution of sex-specific pace-of-life syndromes: genetic architecture and physiological mechanisms.Short-term methionine deprivation improves metabolic health via sexually dimorphic, mTORC1-independent mechanisms.Loss of Malat1 does not modify age- or diet-induced adipose tissue accretion and insulin resistance in mice.

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Sex- and tissue-specific changes in mTOR signaling with age in C57BL/6J mice

http://www.wikidata.org/entity/Q28271425

description

2016 nî lūn-bûn

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2016 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2016 թվականի փետրվարին հրատարակված գիտական հոդված

@hy

2016年の論文

@ja

2016年論文

@yue

2016年論文

@zh-hant

2016年論文

@zh-hk

2016年論文

@zh-mo

2016年論文

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2016年论文

@wuu

name

Sex- and tissue-specific changes in mTOR signaling with age in C57BL/6J mice

@ast

Sex- and tissue-specific changes in mTOR signaling with age in C57BL/6J mice

@en

Sex- and tissue-specific changes in mTOR signaling with age in C57BL/6J mice

@nl

type

label

Sex- and tissue-specific changes in mTOR signaling with age in C57BL/6J mice

@ast

Sex- and tissue-specific changes in mTOR signaling with age in C57BL/6J mice

@en

Sex- and tissue-specific changes in mTOR signaling with age in C57BL/6J mice

@nl

prefLabel

Sex- and tissue-specific changes in mTOR signaling with age in C57BL/6J mice

@ast

Sex- and tissue-specific changes in mTOR signaling with age in C57BL/6J mice

@en

Sex- and tissue-specific changes in mTOR signaling with age in C57BL/6J mice

@nl

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Sex- and tissue-specific changes in mTOR signaling with age in C57BL/6J mice

@en

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Emma L Baar

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Irene M Ong

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Kathryn A Carbajal

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A Tumor suppressor complex with GAP activity for the Rag GTPases that signal amino acid sufficiency to mTORC1

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles.

Extension of chronological life span in yeast by decreased TOR pathway signaling

Rapamycin, but not resveratrol or simvastatin, extends life span of genetically heterogeneous mice

Rapamycin-induced insulin resistance is mediated by mTORC2 loss and uncoupled from longevity

mTOR signaling in growth control and disease

Resveratrol delays age-related deterioration and mimics transcriptional aspects of dietary restriction without extending life span

Up-regulation of phosphorylated/activated p70 S6 kinase and its relationship to neurofibrillary pathology in Alzheimer's disease

A diverse array of cancer-associated MTOR mutations are hyperactivating and can predict rapamycin sensitivity.

Depletion of Rictor, an essential protein component of mTORC2, decreases male lifespan

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155-166

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scholarly article

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1901510

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10.1111/ACEL.12425

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1

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15

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Dudley W Lamming

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2015-11-24T00:00:00Z

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284786407

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26695882

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4717274

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