Ataxia telangiectasia mutated and p21CIP1 modulate cell survival of drug-induced senescent tumor cells: implications for chemotherapy
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Centrosome-associated regulators of the G(2)/M checkpoint as targets for cancer therapyThe Growing Complexity of Cancer Cell Response to DNA-Damaging Agents: Caspase 3 Mediates Cell Death or Survival?Cellular senescence in aging and age-related disease: from mechanisms to therapyDNA Damage Signalling and Repair Inhibitors: The Long-Sought-After Achilles' Heel of CancerOxidative stress-induced DNA damage and cell cycle regulation in B65 dopaminergic cell linep21(WAF1/CIP1) upregulation through the stress granule-associated protein CUGBP1 confers resistance to bortezomib-mediated apoptosis.Common variants near ATM are associated with glycemic response to metformin in type 2 diabetesp53-independent epigenetic repression of the p21(WAF1) gene in T-cell acute lymphoblastic leukemia.Metformin and the ATM DNA damage response (DDR): accelerating the onset of stress-induced senescence to boost protection against cancerThe autophagy-senescence connection in chemotherapy: must tumor cells (self) eat before they sleep?Tetraploidization or autophagy: The ultimate fate of senescent human endometrial stem cells under ATM or p53 inhibitionThe ataxia telangiectasia mutated kinase pathway regulates IL-23 expression by human dendritic cellsNew insights into p53 signaling and cancer cell response to DNA damage: implications for cancer therapy.Ionizing radiation-induced responses in human cells with differing TP53 status.CGK733-induced LC3 II formation is positively associated with the expression of cyclin-dependent kinase inhibitor p21Waf1/Cip1 through modulation of the AMPK and PERK/CHOP signaling pathways.Cell context-dependent involvement of ATR in early stages of retroviral replicationActivation and Inhibition of ATM by Phytochemicals: Awakening and Sleeping the Guardian Angel Naturally.Impact of Premature Senescence on Radiosensitivity Measured by High Throughput Cell-Based Assays.PERK/CHOP contributes to the CGK733-induced vesicular calcium sequestration which is accompanied by non-apoptotic cell deathDominant effects of Δ40p53 on p53 function and melanoma cell fateDown-regulation of wild-type p53-induced phosphatase 1 (Wip1) plays a critical role in regulating several p53-dependent functions in premature senescent tumor cells.ATR controls cellular adaptation to hypoxia through positive regulation of hypoxia-inducible factor 1 (HIF-1) expression.Significance of Wild-Type p53 Signaling in Suppressing Apoptosis in Response to Chemical Genotoxic Agents: Impact on Chemotherapy Outcome.HMGA proteins promote ATM expression and enhance cancer cell resistance to genotoxic agents.NF-κB-dependent cytokine secretion controls Fas expression on chemotherapy-induced premature senescent tumor cells.Switching p53-dependent growth arrest to apoptosis via the inhibition of DNA damage-activated kinases.The ATM and ATR inhibitors CGK733 and caffeine suppress cyclin D1 levels and inhibit cell proliferation.Insight into the role of PIKK family members and NF-кB in DNAdamage-induced senescence and senescence-associated secretory phenotype of colon cancer cells.Trabectedin modulates the senescence-associated secretory phenotype and promotes cell death in senescent tumor cells by targeting NF-κB.MiRNA-106a and prostate cancer radioresistance: a novel role for LITAF in ATM regulation.Roles of Polyploid/Multinucleated Giant Cancer Cells in Metastasis and Disease Relapse Following Anticancer Treatment.Cisplatin resistance reversal by disulfiram and caffeine.
P2860
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P2860
Ataxia telangiectasia mutated and p21CIP1 modulate cell survival of drug-induced senescent tumor cells: implications for chemotherapy
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2008 nî lūn-bûn
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2008 թուականի Մարտին հրատարակուած գիտական յօդուած
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2008 թվականի մարտին հրատարակված գիտական հոդված
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2008年の論文
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2008年論文
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2008年論文
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2008年論文
@zh-hk
2008年論文
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2008年論文
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2008年论文
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name
Ataxia telangiectasia mutated ...... implications for chemotherapy
@ast
Ataxia telangiectasia mutated ...... implications for chemotherapy
@en
Ataxia telangiectasia mutated ...... implications for chemotherapy
@nl
type
label
Ataxia telangiectasia mutated ...... implications for chemotherapy
@ast
Ataxia telangiectasia mutated ...... implications for chemotherapy
@en
Ataxia telangiectasia mutated ...... implications for chemotherapy
@nl
prefLabel
Ataxia telangiectasia mutated ...... implications for chemotherapy
@ast
Ataxia telangiectasia mutated ...... implications for chemotherapy
@en
Ataxia telangiectasia mutated ...... implications for chemotherapy
@nl
P2093
P3181
P1476
Ataxia telangiectasia mutated ...... implications for chemotherapy
@en
P2093
Elvira Crescenzi
Giuseppe Palumbo
Hugh J M Brady
Jasper de Boer
P304
P3181
P356
10.1158/1078-0432.CCR-07-4298
P407
P577
2008-03-15T00:00:00Z