The structure and mechanism of protein phosphatases: insights into catalysis and regulation
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Crystal structures of a purple acid phosphatase, representing different steps of this enzyme's catalytic cycleIdentification of the human YVH1 protein-tyrosine phosphatase orthologue reveals a novel zinc binding domain essential for in vivo functionHuman PIR1 of the protein-tyrosine phosphatase superfamily has RNA 5'-triphosphatase and diphosphatase activitiesInteraction of inhibitor-2 with the catalytic subunit of type 1 protein phosphatase. Identification of a sequence analogous to the consensus type 1 protein phosphatase-binding motifIntramolecular interactions between the juxtamembrane domain and phosphatase domains of receptor protein-tyrosine phosphatase RPTPmu. Regulation of catalytic activityPhosphorylation of the PTEN tail regulates protein stability and functionModulation of integrin signal transduction by ILKAP, a protein phosphatase 2C associating with the integrin-linked kinase, ILK1.Calcium-independent calmodulin binding and two-metal-ion catalytic mechanism of anthrax edema factor.A novel RNA polymerase II C-terminal domain phosphatase that preferentially dephosphorylates serine 5Crystal structures and inhibitor identification for PTPN5, PTPRR and PTPN7: a family of human MAPK-specific protein tyrosine phosphatasesAssociation and regulation of heat shock transcription factor 4b with both extracellular signal-regulated kinase mitogen-activated protein kinase and dual-specificity tyrosine phosphatase DUSP26A novel, evolutionarily conserved protein phosphatase complex involved in cisplatin sensitivityDephosphorylation of the C-terminal tyrosyl residue of the DNA damage-related histone H2A.X is mediated by the protein phosphatase eyes absentLarge-scale structural analysis of the classical human protein tyrosine phosphatomeTIMAP is a positive regulator of pulmonary endothelial barrier functionSmall carboxyl-terminal domain phosphatase 2 attenuates androgen-dependent transcriptionThe C-terminus of NIPP1 (nuclear inhibitor of protein phosphatase-1) contains a novel binding site for protein phosphatase-1 that is controlled by tyrosine phosphorylation and RNA bindingUltrasensitivity in multisite phosphorylation of membrane-anchored proteinsTargeting protein serine/threonine phosphatases for drug developmentThe protein-phosphatome of the human malaria parasite Plasmodium falciparumThe human Vps29 retromer component is a metallo-phosphoesterase for a cation-independent mannose 6-phosphate receptor substrate peptideThe structure of the cell cycle protein Cdc14 reveals a proline-directed protein phosphataseA novel tetratricopeptide repeat (TPR) containing PP5 serine/threonine protein phosphatase in the malaria parasite, Plasmodium falciparumUse of an anaerobic chamber environment for the assay of endogenous cellular protein-tyrosine phosphatase activitiesSignaling regulation of fetoplacental angiogenesisTGF-β cascade regulation by PPP1 and its interactors -impact on prostate cancer development and therapyTurning off AKT: PHLPP as a drug targetTwo membrane-associated tyrosine phosphatase homologs potentiate C. elegans AKT-1/PKB signalingA unique protein phosphatase with kelch-like domains (PPKL) in Plasmodium modulates ookinete differentiation, motility and invasionA test case for structure-based functional assignment: The 1.2 Å crystal structure of the yjgF gene product from Escherichia coliCrystal structure of YegS, a homologue to the mammalian diacylglycerol kinases, reveals a novel regulatory metal binding siteStructural Basis for Selective Inhibition of Mycobacterium tuberculosis Protein Tyrosine Phosphatase PtpBStructure of Streptococcus agalactiae serine/threonine phosphataseCrystal Structure of Pyruvate Dehydrogenase Phosphatase 1 and its Functional ImplicationsSubstrate-Promoted Formation of a Catalytically Competent Binuclear Center and Regulation of Reactivity in a Glycerophosphodiesterase from Enterobacter aerogenesImpaired Acid Catalysis by Mutation of a Protein Loop Hinge Residue in a YopH Mutant Revealed by Crystal StructuresStructural and Functional Characterization of the 2H-Phosphatase Domain of Sts-2 Reveals an Acid-Dependent Phosphatase Activity †Structural insights into the mechanism of abscisic acid signaling by PYL proteinsStructural and functional analysis of the phosphoryl transfer reaction mediated by the human small C-terminal domain phosphatase, Scp1Insights into the Reaction of Protein-tyrosine Phosphatase 1B: CRYSTAL STRUCTURES FOR TRANSITION STATE ANALOGS OF BOTH CATALYTIC STEPS
P2860
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P2860
The structure and mechanism of protein phosphatases: insights into catalysis and regulation
description
1998 nî lūn-bûn
@nan
1998 թուականին հրատարակուած գիտական յօդուած
@hyw
1998 թվականին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
The structure and mechanism of ...... into catalysis and regulation
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The structure and mechanism of ...... into catalysis and regulation
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The structure and mechanism of ...... into catalysis and regulation
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type
label
The structure and mechanism of ...... into catalysis and regulation
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The structure and mechanism of ...... into catalysis and regulation
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The structure and mechanism of ...... into catalysis and regulation
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prefLabel
The structure and mechanism of ...... into catalysis and regulation
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The structure and mechanism of ...... into catalysis and regulation
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The structure and mechanism of ...... into catalysis and regulation
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P2093
P3181
P1476
The structure and mechanism of ...... into catalysis and regulation
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P2093
P304
P3181
P356
10.1146/ANNUREV.BIOPHYS.27.1.133
P407
P577
1998-01-01T00:00:00Z