Calpain in the CNS: from synaptic function to neurotoxicity
about
Tau clearance mechanisms and their possible role in the pathogenesis of Alzheimer diseaseConcerted multi-pronged attack by calpastatin to occlude the catalytic cleft of heterodimeric calpainsEfficacy of antidotes (midazolam, atropine and HI-6) on nerve agent induced molecular and neuropathological changesDistinct regulatory functions of calpain 1 and 2 during neural stem cell self-renewal and differentiationExtrasynaptic NMDA receptors couple preferentially to excitotoxicity via calpain-mediated cleavage of STEPAcute death of astrocytes in blast-exposed rat organotypic hippocampal slice culturesNeurite consolidation is an active process requiring constant repression of protrusive activity.Physiological basis of tingling paresthesia evoked by hydroxy-alpha-sanshool.Human immunodeficiency virus-1 Tat activates calpain proteases via the ryanodine receptor to enhance surface dopamine transporter levels and increase transporter-specific uptake and Vmax.Wallerian-like degeneration of central neurons after synchronized and geometrically registered mass axotomy in a three-compartmental microfluidic chipCalpain and proteasomal regulation of antiretroviral zinc finger protein OTK18 in human macrophages: visualization in live cells by intramolecular FRET.17-Beta-estradiol increases neuronal excitability through MAP kinase-induced calpain activationGPS-CCD: a novel computational program for the prediction of calpain cleavage sites.Calpain cleavage prediction using multiple kernel learning.Overexpression of the calpain-specific inhibitor calpastatin reduces human alpha-Synuclein processing, aggregation and synaptic impairment in [A30P]αSyn transgenic mice.Calpain cleavage of brain glutamic acid decarboxylase 65 is pathological and impairs GABA neurotransmission.Calpain 1 knockdown improves tissue sparing and functional outcomes after spinal cord injury in rats.The ankyrin repeat-rich membrane spanning (ARMS)/Kidins220 scaffold protein is regulated by activity-dependent calpain proteolysis and modulates synaptic plasticity.Regulation of GABAergic synapse formation and plasticity by GSK3beta-dependent phosphorylation of gephyrin.Blood-based diagnostics of traumatic brain injuries.Effect of hypoxia on expression of selected proteins involved in regulation of apoptotic activity in striatum of newborn piglets.Interaction between calpain-1 and HSP90: new insights into the regulation of localization and activity of the protease.Calpain-mediated tau cleavage: a mechanism leading to neurodegeneration shared by multiple tauopathiesCalpain chronicle--an enzyme family under multidisciplinary characterizationCalpain dysregulation in Alzheimer's diseaseRaised Intracellular Calcium Contributes to Ischemia-Induced Depression of Evoked Synaptic Transmission.Loss of calbindin-D28K is associated with the full range of tangle pathology within basal forebrain cholinergic neurons in Alzheimer's diseaseBiomarkers of HIV-1-associated neurocognitive disorders: challenges of proteomic approachesALLN rescues an in vitro excitatory synaptic transmission deficit in Lis1 mutant miceEndocytosis of somatodendritic NCKX2 is regulated by Src family kinase-dependent tyrosine phosphorylationOverexpression of μ-calpain in the anterior temporal neocortex of patients with intractable epilepsy correlates with clinicopathological characteristicsAccumulation of human full-length tau induces degradation of nicotinic acetylcholine receptor α4 via activating calpain-2.Defects in the CAPN1 Gene Result in Alterations in Cerebellar Development and Cerebellar Ataxia in Mice and Humans.Differential Activation of Calpain-1 and Calpain-2 following Kainate-Induced Seizure Activity in Rats and Mice.Distinct roles for μ-calpain and m-calpain in synaptic NMDAR-mediated neuroprotection and extrasynaptic NMDAR-mediated neurodegeneration.Mechanical membrane injury induces axonal beading through localized activation of calpainBiochemical, structural, and biomarker evidence for calpain-mediated cytoskeletal change after diffuse brain injury uncomplicated by contusion.Inhibition of Histone Deacetylase 3 (HDAC3) Mediates Ischemic Preconditioning and Protects Cortical Neurons against Ischemia in RatsCritical role of astrocytic interleukin-17 A in post-stroke survival and neuronal differentiation of neural precursor cells in adult miceThalamo-cortical axons regulate the radial dispersion of neocortical GABAergic interneurons.
P2860
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P2860
Calpain in the CNS: from synaptic function to neurotoxicity
description
2008 nî lūn-bûn
@nan
2008 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Calpain in the CNS: from synaptic function to neurotoxicity
@ast
Calpain in the CNS: from synaptic function to neurotoxicity
@en
Calpain in the CNS: from synaptic function to neurotoxicity
@nl
type
label
Calpain in the CNS: from synaptic function to neurotoxicity
@ast
Calpain in the CNS: from synaptic function to neurotoxicity
@en
Calpain in the CNS: from synaptic function to neurotoxicity
@nl
prefLabel
Calpain in the CNS: from synaptic function to neurotoxicity
@ast
Calpain in the CNS: from synaptic function to neurotoxicity
@en
Calpain in the CNS: from synaptic function to neurotoxicity
@nl
P3181
P356
P1433
P1476
Calpain in the CNS: from synaptic function to neurotoxicity
@en
P2093
Ming Cheng Liu
P3181
P356
10.1126/STKE.114RE1
P407
P577
2008-04-08T00:00:00Z