Cloning, sequencing and expression of human TSH receptor
about
Two-subunit structure of the human thyrotropin receptorArg60 to Leu mutation of the human thromboxane A2 receptor in a dominantly inherited bleeding disorderCloning, chromosomal assignment, and regulation of the rat thyrotropin receptor: expression of the gene is regulated by thyrotropin, agents that increase cAMP levels, and thyroid autoantibodiesTSH signalling and cancer.Structural-Functional Features of the Thyrotropin Receptor: A Class A G-Protein-Coupled Receptor at WorkThyrotropin receptor-associated diseases: from adenomata to Graves diseaseThe genetics of the thyroid stimulating hormone receptor: history and relevanceBinding domains of stimulatory and inhibitory thyrotropin (TSH) receptor autoantibodies determined with chimeric TSH-lutropin/chorionic gonadotropin receptors.Defining thyrotropin-dependent and -independent steps of thyroid hormone synthesis by using thyrotropin receptor-null mice.The TSH receptor reveals itself.Molecular cloning, genomic organization, developmental regulation, and a knock-out mutant of a novel leu-rich repeats-containing G protein-coupled receptor (DLGR-2) from Drosophila melanogaster.Molecular basis for the autoreactivity against thyroid stimulating hormone receptor.Immunogenetic mechanisms leading to thyroid autoimmunity: recent advances in identifying susceptibility genes and regions.Deleting the Redundant TSH Receptor C-Peptide Region Permits Generation of the Conformationally Intact Extracellular Domain by Insect Cells.Expression of thyrotrophin receptor gene in thyroid carcinoma is associated with a good prognosis.TSH Receptor Cleavage Into Subunits and Shedding of the A-Subunit; A Molecular and Clinical Perspective.Novel insights on thyroid-stimulating hormone receptor signal transduction.Familial congenital hypothyroidism due to inactivating mutation of the thyrotropin receptor causing profound hypoplasia of the thyroid gland.Thyrotropin-luteinizing hormone/chorionic gonadotropin receptor extracellular domain chimeras as probes for thyrotropin receptor function.Direct evidence that ganglioside is an integral component of the thyrotropin receptor.Localization and synthesis of the hormone-binding regions of the human thyrotropin receptor.The heterodimeric glycoprotein hormone, GPA2/GPB5, regulates ion transport across the hindgut of the adult mosquito, Aedes aegypti.Significance of the carbohydrate moiety of the rat ovarian luteinizing-hormone/chorionic-gonadotropin receptor for ligand-binding specificity and signal transduction.Molecular cloning of a human thyrotropin receptor cDNA fragment. Use of highly degenerate, inosine containing primers derived from aligned amino acid sequences of a homologous family of glycoprotein hormone receptors.TSH receptor status of thyroid neoplasms--TaqMan RT-PCR analysis of archival material.Transcriptional repressor DREAM interacts with thyroid transcription factor-1 and regulates thyroglobulin gene expression.Engineering the human thyrotropin receptor ectodomain from a non-secreted form to a secreted, highly immunoreactive glycoprotein that neutralizes autoantibodies in Graves' patients' sera.Autoantibodies interacting with purified native thyrotropin receptor.Basolateral localization and transcytosis of gonadotropin and thyrotropin receptors expressed in Madin-Darby canine kidney cells.Shedding of human thyrotropin receptor ectodomain. Involvement of a matrix metalloprotease.Differential roles of exoloop 1 of the human follicle-stimulating hormone receptor in hormone binding and receptor activation.Molecular insights into TSH receptor abnormality and thyroid disease.Analysis of human TSH receptor gene and RNA transcripts in patients with thyroid disorders.Induction of TSH binding inhibitory immunoglobulins with the extracellular domain of human thyrotropin receptor produced using baculovirus expression system.Enhanced cAMP accumulation by the human thyrotropin receptor variant with the Pro52Thr substitution in the extracellular domain.Measurement of cAMP accumulation in Chinese hamster ovary cells transfected with the recombinant human TSH receptor (CHO-R): a new bioassay for human thyrotropin.Induction of hyperthyroidism in mice by intradermal immunization with DNA encoding the thyrotropin receptor.An N-linked glycosylation motif from the noncleaving luteinizing hormone receptor substituted for the homologous region (Gly367 to Glu369) of the thyrotropin receptor prevents cleavage at its second, downstream site.Molecular cloning, genomic organization, and developmental regulation of a novel receptor from Drosophila melanogaster structurally related to members of the thyroid-stimulating hormone, follicle-stimulating hormone, luteinizing hormone/choriogonado
P2860
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P2860
Cloning, sequencing and expression of human TSH receptor
description
1990 nî lūn-bûn
@nan
1990 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1990 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1990年の論文
@ja
1990年論文
@yue
1990年論文
@zh-hant
1990年論文
@zh-hk
1990年論文
@zh-mo
1990年論文
@zh-tw
1990年论文
@wuu
name
Cloning, sequencing and expression of human TSH receptor
@ast
Cloning, sequencing and expression of human TSH receptor
@en
Cloning, sequencing and expression of human TSH receptor
@nl
type
label
Cloning, sequencing and expression of human TSH receptor
@ast
Cloning, sequencing and expression of human TSH receptor
@en
Cloning, sequencing and expression of human TSH receptor
@nl
prefLabel
Cloning, sequencing and expression of human TSH receptor
@ast
Cloning, sequencing and expression of human TSH receptor
@en
Cloning, sequencing and expression of human TSH receptor
@nl
P2093
P1476
Cloning, sequencing and expression of human TSH receptor
@en
P2093
P304
P356
10.1016/0006-291X(90)91958-U
P407
P577
1990-01-15T00:00:00Z