about
The mutant form of lamin A that causes Hutchinson-Gilford progeria is a biomarker of cellular aging in human skinMolecular ageing in progeroid syndromes: Hutchinson-Gilford progeria syndrome as a modelThe nuclear envelopathies and human diseasesLamin A/C haploinsufficiency modulates the differentiation potential of mouse embryonic stem cellsSumoylation regulates lamin A function and is lost in lamin A mutants associated with familial cardiomyopathiesLINC complex alterations in DMD and EDMD/CMT fibroblastsProgeria: a rare genetic premature ageing disorderPhenotype and course of Hutchinson-Gilford progeria syndromeProgerin and telomere dysfunction collaborate to trigger cellular senescence in normal human fibroblastsMutations in the nervous system--specific HSN2 exon of WNK1 cause hereditary sensory neuropathy type IIA farnesyltransferase inhibitor prevents both the onset and late progression of cardiovascular disease in a progeria mouse modelMouse models of laminopathiesNuclear assembly as a target for anti-cancer therapiesThe nuclear envelope as a chromatin organizerRole for perinuclear chromosome tethering in maintenance of genome stability.Surveillance of nuclear pore complex assembly by ESCRT-III/Vps4.Analysis of prelamin A biogenesis reveals the nucleus to be a CaaX processing compartmentRecent advances in understanding the role of lamins in health and diseaseInherited bradyarrhythmia: A diverse genetic backgroundRecent advances in animal and human pluripotent stem cell modeling of cardiac laminopathyNuclear envelope structural proteins facilitate nuclear shape changes accompanying embryonic differentiation and fidelity of gene expressionLamin b1 polymorphism influences morphology of the nuclear envelope, cell cycle progression, and risk of neural tube defects in miceHow Research on Human Progeroid and Antigeroid Syndromes Can Contribute to the Longevity Dividend InitiativeAgeing-related chromatin defects through loss of the NURD complexMonoclonal antibodies specific for disease-associated point-mutants: lamin A/C R453W and R482WGenotype-phenotype associations in dilated cardiomyopathy: meta-analysis on more than 8000 individuals.mTOR complex 1 regulates lipin 1 localization to control the SREBP pathway.Is LMNB1 a susceptibility gene for neural tube defects in humans?Loss of GATA6 leads to nuclear deformation and aneuploidy in ovarian cancer.Farnesylated nuclear proteins Kugelkern and lamin Dm0 affect nuclear morphology by directly interacting with the nuclear membrane.Novel nesprin-1 mutations associated with dilated cardiomyopathy cause nuclear envelope disruption and defects in myogenesis.Barrier-to-autointegration factor proteome reveals chromatin-regulatory partners.Intermediate filaments: a historical perspectiveFitting the pieces of the puzzle together: a case report of the Dunnigan-type of familial partial lipodystrophy in the adolescent girlDifferential expression of A-type and B-type lamins during hair cycling.Disheveled hair and ear (Dhe), a spontaneous mouse Lmna mutation modeling human laminopathies.Lamin A rod domain mutants target heterochromatin protein 1alpha and beta for proteasomal degradation by activation of F-box protein, FBXW10Dynamics of lamin-A processing following precursor accumulation.Nuclear localization signal deletion mutants of lamin A and progerin reveal insights into lamin A processing and emerin targetingLamina-associated polypeptide 2alpha loss impairs heart function and stress response in mice.
P2860
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P2860
description
2006 nî lūn-bûn
@nan
2006 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Human laminopathies: nuclei gone genetically awry
@ast
Human laminopathies: nuclei gone genetically awry
@en
Human laminopathies: nuclei gone genetically awry
@nl
type
label
Human laminopathies: nuclei gone genetically awry
@ast
Human laminopathies: nuclei gone genetically awry
@en
Human laminopathies: nuclei gone genetically awry
@nl
prefLabel
Human laminopathies: nuclei gone genetically awry
@ast
Human laminopathies: nuclei gone genetically awry
@en
Human laminopathies: nuclei gone genetically awry
@nl
P3181
P356
P1476
Human laminopathies: nuclei gone genetically awry
@en
P2888
P304
P3181
P356
10.1038/NRG1906
P407
P577
2006-12-01T00:00:00Z
P5875
P6179
1020031345