Genotype-phenotype correlation between the polymorphic UGT2B17 gene deletion and NNAL glucuronidation activities in human liver microsomes
about
Urinary biomarkers of smokers' exposure to tobacco smoke constituents in tobacco products assessment: a fit for purpose approachInterindividual variability in hepatic drug glucuronidation: studies into the role of age, sex, enzyme inducers, and genetic polymorphism using the human liver bank as a model system.Meta-analysis reveals a lack of association between UGT2B17 deletion polymorphism and tumor susceptibility.Nicotine metabolism in African Americans and European Americans: variation in glucuronidation by ethnicity and UGT2B10 haplotype.UDP-glucuronosyltransferase 1A10: activity against the tobacco-specific nitrosamine, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol, and a potential role for a novel UGT1A10 promoter deletion polymorphism in cancer susceptibility.The functional impact of structural variation in humans.Glucuronidation genotypes and nicotine metabolic phenotypes: importance of functional UGT2B10 and UGT2B17 polymorphismsCharacterization of UDP-glucuronosyltransferase 2A1 (UGT2A1) variants and their potential role in tobacco carcinogenesis.Associations between polymorphisms in glucuronidation and sulfation enzymes and sex steroid concentrations in premenopausal women in the United StatesCopy number alterations in urothelial carcinomas: their clinicopathological significance and correlation with DNA methylation alterationsCharacterization of 17-dihydroexemestane glucuronidation: potential role of the UGT2B17 deletion in exemestane pharmacogenetics.Variation in trans-3'-hydroxycotinine glucuronidation does not alter the nicotine metabolite ratio or nicotine intake.UGT1A and UGT2B genetic variation alters nicotine and nitrosamine glucuronidation in european and african american smokers.Uridine 5'-diphospho-glucuronosyltransferase genetic polymorphisms and response to cancer chemotherapy.Homozygous deletions of UGT2B17 modifies effects of smoking on TP53-mutations and relapse of head and neck carcinomaGlucuronidation of trans-3'-hydroxycotinine by UGT2B17 and UGT2B10.Germline copy number loss of UGT2B28 and gain of PLEC contribute to increased human esophageal squamous cell carcinoma risk in Southwest China.Identification and functional characterization of a novel UDP-glucuronosyltransferase 2A1 splice variant: potential importance in tobacco-related cancer susceptibility.A pharmacogenomics primer.Effects of menthol on tobacco smoke exposure, nicotine dependence, and NNAL glucuronidation.Functional significance of UDP-glucuronosyltransferase variants in the metabolism of active tamoxifen metabolitesHigh throughput liquid and gas chromatography-tandem mass spectrometry assays for tobacco-specific nitrosamine and polycyclic aromatic hydrocarbon metabolites associated with lung cancer in smokers.Glucuronidation of tobacco-specific nitrosamines by UGT2B10Association between Glucuronidation Genotypes and Urinary NNAL Metabolic Phenotypes in Smokers.Exposure to the carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in smokers from 3 populations with different risks of lung cancer.UGT2B gene expression analysis in multiple tobacco carcinogen-targeted tissues.Genetic polymorphisms of human UDP-glucuronosyltransferase (UGT) genes and cancer risk.Role of the UGT2B17 deletion in exemestane pharmacogenetics.Characterization of UGTs active against SAHA and association between SAHA glucuronidation activity phenotype with UGT genotype.A new liquid chromatography/mass spectrometry method for 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) in urine.NNK reduction pathway gene polymorphisms and risk of lung cancer.Influence of UGT2B10 genotype on urinary excretion of NNAL-N-glucuronide by African American smokers.Combined effect of genetic polymorphisms in phase I and II biotransformation enzymes on head and neck cancer risk.
P2860
Q28662000-A326C13E-BA74-464B-A911-5589FA8A07B5Q33451969-140749B1-713C-4D94-A02F-F7EF54C39D0AQ33573400-36825F9F-36C8-459F-A5A6-999A9BF92CFBQ33574895-7DE65C70-783B-4BEC-BFE1-9A4451DD3CA5Q33714575-B3CE1272-0F5C-40C6-9706-0629A1B595CAQ33847296-8430172C-7186-4C7A-8F00-E9C619B6B60EQ34390412-3AA9C1CB-C4C2-4942-A1C4-2FD071ED9926Q34482453-9FCE8C47-5078-4777-8445-14D00CC8E805Q34730731-BA07B708-9D1D-4058-AB9A-94E4C0968EF7Q34734078-BBD19BCB-2F59-4968-9171-5DE9F1099527Q34793489-3DAFBD91-2C35-45B4-983E-E50CF0053F0AQ34926339-FA6E77F9-85C4-4960-A80F-EE9B8BF2AC54Q34964392-44319774-E137-412C-B094-6259461E0684Q35008045-427C38A4-F90F-4F21-9DC7-27366AE346BAQ35319092-4D1D2CE2-355E-43C8-A276-53CD455AB5DAQ35745357-AA3B5394-D354-44A1-B34D-8C7C2C552087Q36309393-5BBE1282-8EB1-41B8-BBF2-64FCCF9DC7ECQ36406279-865398B4-4A63-4040-9846-C6037FCD44BEQ36896796-5555C170-DA6D-4310-83D9-EAB259DF23AAQ37178887-A0C68A42-C056-4DE0-8389-2A1F29BFD24AQ37195375-86B6CB47-575B-4491-908B-567C6343D604Q37243159-65BDFF50-D2B2-4C39-A3B1-56E932970991Q37271209-7E85B9F5-AA69-4775-8ECA-AAD803FEB23BQ37381909-92558205-81B4-493A-9AB3-16BA6B098BA8Q37426846-442F300A-7DBB-4722-95A3-17CFD6AFEBC4Q37663398-F9D71E34-7233-45F6-BD3C-224BE40EAE2CQ38717288-808BA297-6E4D-488D-AB8B-0FBB6AA7155AQ38769425-7AADB1E3-5077-44FF-BE8D-56BBCA560525Q39868674-36572913-0F6C-4265-ADDD-31677850B3EAQ42154700-B5EC3B2E-A920-4CAB-A6C1-3EF87667114AQ48852585-019287F8-2B74-476A-99F0-854131319C4AQ49820994-59094B03-7BCE-416A-A51B-EFBD98EC1817Q53268985-C9573795-FB48-468A-9CEF-C179EF637683
P2860
Genotype-phenotype correlation between the polymorphic UGT2B17 gene deletion and NNAL glucuronidation activities in human liver microsomes
description
2005 nî lūn-bûn
@nan
2005 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Genotype-phenotype correlation ...... ties in human liver microsomes
@ast
Genotype-phenotype correlation ...... ties in human liver microsomes
@en
Genotype-phenotype correlation ...... ties in human liver microsomes
@nl
type
label
Genotype-phenotype correlation ...... ties in human liver microsomes
@ast
Genotype-phenotype correlation ...... ties in human liver microsomes
@en
Genotype-phenotype correlation ...... ties in human liver microsomes
@nl
prefLabel
Genotype-phenotype correlation ...... ties in human liver microsomes
@ast
Genotype-phenotype correlation ...... ties in human liver microsomes
@en
Genotype-phenotype correlation ...... ties in human liver microsomes
@nl
P2093
P1476
Genotype-phenotype correlation ...... ties in human liver microsomes
@en
P2093
Doris Wiener
E Aaron Runkle
Joshua E Muscat
Philip Lazarus
P304
P356
10.1097/01.FPC.0000175596.52443.EF
P407
P577
2005-11-01T00:00:00Z