Multiple roles of the DSCR1 (Adapt78 or RCAN1) gene and its protein product calcipressin 1 (or RCAN1) in disease
about
Protein Ser/Thr phosphatases--the ugly ducklings of cell signalling.NF-kappaB-inducing kinase phosphorylates and blocks the degradation of Down syndrome candidate region 1.Gene expression signature of cerebellar hypoplasia in a mouse model of Down syndrome during postnatal development.Commonality in Down and fetal alcohol syndromes.Calcineurin as a Multifunctional Regulator: Unraveling Novel Functions in Fungal Stress Responses, Hyphal Growth, Drug Resistance, and PathogenesisPituitary Adenylate Cyclase-activating Polypeptide (PACAP) Targets Down Syndrome Candidate Region 1 (DSCR1/RCAN1) to control Neuronal Differentiation.Genetic variants within obesity-related genes are associated with tumor recurrence in patients with stages II/III colon cancer.Rescue of calcineurin Aα(-/-) mice reveals a novel role for the α isoform in the salivary gland.What Are the bona fide GSK3 Substrates?Regulator of calcineurin 1 (Rcan1) is required for the development of pulmonary eosinophilia in allergic inflammation in miceThe regulator of calcineurin 1 (RCAN1/DSCR1) activates the cAMP response element-binding protein (CREB) pathwayChronic expression of RCAN1-1L protein induces mitochondrial autophagy and metabolic shift from oxidative phosphorylation to glycolysis in neuronal cells.Antioxidants in Down syndrome.Tumour angiogenesis is reduced in the Tc1 mouse model of Down's syndrome.Free radical biology and medicine: it's a gas, man!Overexpression of Dyrk1A contributes to neurofibrillary degeneration in Down syndrome.Amyloid-β toxicity and tau hyperphosphorylation are linked via RCAN1 in Alzheimer's disease.Calcineurin regulation in fungi and beyondRcan1 negatively regulates Fc epsilonRI-mediated signaling and mast cell function.Trisomy 21 and Down syndrome: a short review.Down syndrome critical region 1 enhances the proteolytic cleavage of calcineurin.Novel inhibitors of the calcineurin/NFATc hub - alternatives to CsA and FK506?Chronic high levels of the RCAN1-1 protein may promote neurodegeneration and Alzheimer disease.Functional genomic analysis reveals cross-talk between peroxisome proliferator-activated receptor gamma and calcium signaling in human colorectal cancer cells.The Proteasome and Oxidative Stress in Alzheimer's Disease.Calcineurin in fungal virulence and drug resistance: Prospects for harnessing targeted inhibition of calcineurin for an antifungal therapeutic approach.RCAN1.4 regulates VEGFR-2 internalisation, cell polarity and migration in human microvascular endothelial cells.Deletion of hexose-6-phosphate dehydrogenase activates the unfolded protein response pathway and induces skeletal myopathy.Ubiquitin-specific protease 22 (USP22) positively regulates RCAN1 protein levels through RCAN1 de-ubiquitination.Cell line profiling to improve monoclonal antibody production.Activation of adenylate cyclase by forskolin increases the protein stability of RCAN1 (DSCR1 or Adapt78).RCAN1-4 knockdown attenuates cell growth through the inhibition of Ras signaling.Down syndrome candidate region 1 increases the stability of the IkappaBalpha protein: implications for its anti-inflammatory effects.Regulator of Calcineurin 1 in Periodontal Disease.Peroxisome proliferator activated receptor-γ and the ubiquitin-proteasome system in colorectal cancer.A major role for RCAN1 in atherosclerosis progressionGlucocorticoid evoked upregulation of RCAN1-1 in human leukemic CEM cells susceptible to apoptosis.Inflammatory and Immunological parameters in adults with Down syndromeFoxo transcription factors blunt cardiac hypertrophy by inhibiting calcineurin signalingKnockdown of RCAN1.4 Increases Susceptibility to FAS-mediated and DNA-damage-induced Apoptosis by Upregulation of p53 Expression.
P2860
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P2860
Multiple roles of the DSCR1 (Adapt78 or RCAN1) gene and its protein product calcipressin 1 (or RCAN1) in disease
description
2005 nî lūn-bûn
@nan
2005 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Multiple roles of the DSCR1 (A ...... ressin 1 (or RCAN1) in disease
@ast
Multiple roles of the DSCR1 (A ...... ressin 1 (or RCAN1) in disease
@en
Multiple roles of the DSCR1 (A ...... ressin 1 (or RCAN1) in disease
@nl
type
label
Multiple roles of the DSCR1 (A ...... ressin 1 (or RCAN1) in disease
@ast
Multiple roles of the DSCR1 (A ...... ressin 1 (or RCAN1) in disease
@en
Multiple roles of the DSCR1 (A ...... ressin 1 (or RCAN1) in disease
@nl
prefLabel
Multiple roles of the DSCR1 (A ...... ressin 1 (or RCAN1) in disease
@ast
Multiple roles of the DSCR1 (A ...... ressin 1 (or RCAN1) in disease
@en
Multiple roles of the DSCR1 (A ...... ressin 1 (or RCAN1) in disease
@nl
P3181
P1476
Multiple roles of the DSCR1 (A ...... ressin 1 (or RCAN1) in disease
@en
P2093
P2888
P304
P3181
P356
10.1007/S00018-005-5085-4
P407
P50
P577
2005-11-01T00:00:00Z