FXR regulates organic solute transporters alpha and beta in the adrenal gland, kidney, and intestine - Wikidata - wikimedia - TriplyDB

FXR regulates organic solute transporters alpha and beta in the adrenal gland, kidney, and intestine

FXR regulates organic solute transporters alpha and beta in the adrenal gland, kidney, and intestine

http://www.wikidata.org/entity/Q28279170

about

The organic solute transporter alpha-beta, Ostalpha-Ostbeta, is essential for intestinal bile acid transport and homeostasis Bile acid transporters FXR signaling in the enterohepatic system Bile acid nuclear receptor FXR and digestive system diseases Bile acid signaling in metabolic disease and drug therapy Upregulation of a basolateral FXR-dependent bile acid efflux transporter OSTalpha-OSTbeta in cholestasis in humans and rodents Heterodimerization, trafficking and membrane topology of the two proteins, Ost alpha and Ost beta, that constitute the organic solute and steroid transporter Neurosteroid transport by the organic solute transporter OSTα-OSTβ.Identification of novel pathways that control farnesoid X receptor-mediated hypocholesterolemia.Bile acid-induced elevated oxidative stress in the absence of farnesoid X receptor.Clinical application of transcriptional activators of bile salt transporters.Getting the mOST from OST: Role of organic solute transporter, OSTalpha-OSTbeta, in bile acid and steroid metabolism.Transcriptional regulation of the intestinal nuclear bile acid farnesoid X receptor (FXR) by the caudal-related homeobox 2 (CDX2).The heteromeric organic solute transporter, OSTα-OSTβ/SLC51: a transporter for steroid-derived molecules Association of genetic variation in the NR1H4 gene, encoding the nuclear bile acid receptor FXR, with inflammatory bowel disease.Endocrine functions of bile acids.Deciphering the nuclear bile acid receptor FXR paradigm.Aldo-keto reductase 1B7 is a target gene of FXR and regulates lipid and glucose homeostasis Molecular mechanisms of altered bile acid homeostasis in organic solute transporter-alpha knockout mice.Unusual binding of ursodeoxycholic acid to ileal bile acid binding protein: role in activation of FXRα Orally Administered Berberine Modulates Hepatic Lipid Metabolism by Altering Microbial Bile Acid Metabolism and the Intestinal FXR Signaling Pathway.FXR: a target for cholestatic syndromes?Does abnormal bile acid metabolism contribute to NEC?Arachidonic acid-induced expression of the organic solute and steroid transporter-beta (Ost-beta) in a cartilaginous fish cell line Ostalpha-Ostbeta is required for bile acid and conjugated steroid disposition in the intestine, kidney, and liver.Pleiotropic roles of bile acids in metabolism.Bacterial-dependent up-regulation of intestinal bile acid binding protein and transport is FXR-mediated following ileo-cecal resection.Pharmacology of bile acid receptors: Evolution of bile acids from simple detergents to complex signaling molecules.The farnesoid X receptor regulates transcription of 3beta-hydroxysteroid dehydrogenase type 2 in human adrenal cells.Farnesoid X receptor deficiency in mice leads to increased intestinal epithelial cell proliferation and tumor development OST alpha-OST beta: a key membrane transporter of bile acids and conjugated steroids.Nuclear receptors as therapeutic targets in cholestatic liver diseases.The role of FXR in disorders of bile acid homeostasis.A novel RARα/CAR-mediated mechanism for regulation of human organic solute transporter-β gene expression.Farnesoid X receptor (FXR) gene deficiency impairs urine concentration in mice.Organic solute transporter, OSTalpha-OSTbeta: its role in bile acid transport and cholestasis.Lipid-sensing nuclear receptors in the pathophysiology and treatment of the metabolic syndrome.Nuclear receptors in bile acid metabolism Nuclear receptor control of enterohepatic circulation.Bile acid receptors as targets for drug development.

P2860

Q24651870-12E6D7FA-5640-4DF5-9159-E8268205BA63 Q24652624-EC4D86CB-7723-4DE1-BBED-D917E9E78C4E Q27014753-03FFC357-D58F-42A7-9EE0-418C96C4A56C Q28085493-A9D6E756-081E-4D9F-83FA-EE0BC1B5FAF9 Q28244875-3C0D92A4-2BD8-4D63-B695-0D29633AD8F7 Q28292663-7D7FA955-41F7-47C0-89D3-C40E9E342B9C Q28509995-1EB48EDE-548F-4A85-B5DE-931C35E63F1B Q33637849-C1622813-1050-4C60-8FB0-AB0DBDA3E589 Q33661459-43E1BDEE-06EE-4CFE-811D-01FF5B1FBB61 Q33693402-8BB826E7-BF59-4135-A2D5-9AC2F1FE0032 Q33709930-2AA2D739-2F84-49AE-B843-9E80548A37B6 Q34024552-6039703C-3C3A-49C5-859E-9E6729DB6268 Q34317385-21CF8A99-7145-442D-9DA6-FBBA5FCA8BE7 Q34333722-D3F5B891-42B6-44BA-89AF-E2515F2A149E Q34396606-B7268BE2-EE62-401C-A94F-07DD3C5D2E90 Q34545426-A0A952FD-220F-41AE-9285-F697DEA663FF Q34626518-3B9A80F5-4FFA-4613-B592-7BAC32971C59 Q35107308-3AFB84AD-7665-4317-A90A-53540E72718D Q35459985-2EF681E1-82EC-4F47-B81D-6921D0B20530 Q35839661-C9A6C391-894D-4FE2-931E-7229C9260213 Q36216779-AFE55E63-EFC4-4391-BBC2-31F0AFB7C454 Q36481061-D45AE4A2-0399-4B7E-BE2E-C3151E68E71F Q36580017-0255EEAC-7C90-4824-A8C1-530B73B54414 Q36774212-1265E29E-2F2D-410E-B45A-0F01DD76BB22 Q36807819-1F2ACDA3-A9A0-4850-8E03-8B9A5596EFC0 Q36843966-5DD49ECB-B1AB-4FC2-9EFE-706A533A5884 Q36865909-68A68DC9-E56F-4739-A7E1-189CCFD3255B Q36987335-CBA9C6F0-3235-48EF-B978-57B01148B224 Q37184702-4F8944A9-65F4-458E-A8D3-289641FB6867 Q37192731-2ADDE0A1-6447-40E0-9A62-88CBD15BBFF7 Q37222442-236C4E03-6B84-4A76-BA3D-F3E6E106969D Q37230857-22983FAF-6251-40A4-A5D7-2DAACD1E84C2 Q37300843-693FA3FB-70DA-4D60-92C2-044462C4E16D Q37575651-CE3AE606-D022-49F8-AAA3-254E4054ED8C Q37587745-3011AF45-EB3F-480D-9597-2A5ADFC2B6B7 Q37737636-3FEFF9DE-21F9-4006-BF6A-3713B213AD33 Q37900938-1B7CD8A9-248C-4A0F-9EA9-6E194213729F Q38074995-EC861B26-A922-43D9-A93D-17FB69DBE5C0 Q38110503-11FC8ACB-D605-40CE-8819-6ABCB74FAB1F Q38132058-329866DC-3972-486A-87C8-B0A39762D746

P2860

FXR regulates organic solute transporters alpha and beta in the adrenal gland, kidney, and intestine

http://www.wikidata.org/entity/Q28279170

description

2006 nî lūn-bûn

@nan

2006 թուականի Յունուարին հրատարակուած գիտական յօդուած

@hyw

2006 թվականի հունվարին հրատարակված գիտական հոդված

@hy

2006年の論文

@ja

2006年論文

@yue

2006年論文

@zh-hant

2006年論文

@zh-hk

2006年論文

@zh-mo

2006年論文

@zh-tw

2006年论文

@wuu

name

FXR regulates organic solute t ...... l gland, kidney, and intestine

@ast

FXR regulates organic solute t ...... l gland, kidney, and intestine

@en

FXR regulates organic solute t ...... l gland, kidney, and intestine

@nl

type

label

FXR regulates organic solute t ...... l gland, kidney, and intestine

@ast

FXR regulates organic solute t ...... l gland, kidney, and intestine

@en

FXR regulates organic solute t ...... l gland, kidney, and intestine

@nl

prefLabel

FXR regulates organic solute t ...... l gland, kidney, and intestine

@ast

FXR regulates organic solute t ...... l gland, kidney, and intestine

@en

FXR regulates organic solute t ...... l gland, kidney, and intestine

@nl

P1433

Q28279170-C0CAC388-4857-44D9-A68A-4BB6FC08852C

P1476

Q28279170-484763C6-C011-4796-81DE-1872D1DE5874

P2093

Q28279170-59E53DD5-0DF7-480D-8B6D-80E0E26E39E1

Q28279170-9ED524A0-B75E-4EE2-A51D-FBEF91F7F899

Q28279170-AF97CB93-A01C-4D24-953B-3A0A4BFF27B2

Q28279170-CF8531C5-6FDA-4DDA-B89A-D705F12F2DFE

Q28279170-E15BA62D-6BEC-48F5-A9F4-E327DF9FB084

Q28279170-E48D95E5-1F1E-417E-B4CD-723AAD6DC436

P304

Q28279170-16D32F95-380C-4147-9A65-7EE6E51587D8

P31

Q28279170-21B1E635-B643-4D24-8B03-9F9A896CD2E0

P356

Q28279170-9FBA5235-A1FB-47D2-A456-DFC43B563F53

P407

Q28279170-752994F5-157D-49EC-84E1-A6378546A6A0

P433

Q28279170-900D82AF-7AFB-4FE6-B127-A806C3684879

P478

Q28279170-DBB64FE8-6DAD-4C26-B70D-C0DA77089DD9

P577

Q28279170-D15D3437-3044-4517-A2BA-5F84FCF6EF79

P5875

Q28279170-CBA16550-E2CE-45BE-BF06-63251D8AD830

P698

Q28279170-72BADF9B-0FC9-4F46-9644-7B90222B2EA5

P356

JLR.M500417-JLR200

P1433

Journal of Lipid Research

P1476

FXR regulates organic solute t ...... l gland, kidney, and intestine

@en

P2093

Florence Y Lee

http://www.w3.org/2001/XMLSchema#string

Frank J Gonzalez

http://www.w3.org/2001/XMLSchema#string

Hans Lee

http://www.w3.org/2001/XMLSchema#string

Peter A Edwards

http://www.w3.org/2001/XMLSchema#string

Stanley F Nelson

http://www.w3.org/2001/XMLSchema#string

Yanqiao Zhang

http://www.w3.org/2001/XMLSchema#string

P304

201-14

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1194/JLR.M500417-JLR200

http://www.w3.org/2001/XMLSchema#string

P407

P433

1

http://www.w3.org/2001/XMLSchema#string

P478

47

http://www.w3.org/2001/XMLSchema#string

P577

2006-01-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

7514524

http://www.w3.org/2001/XMLSchema#string

P698

16251721

http://www.w3.org/2001/XMLSchema#string