Induction of cyclooxygenase-2 by activated Ha-ras oncogene in Rat-1 fibroblasts and the role of mitogen-activated protein kinase pathway
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NHERF2 specifically interacts with LPA2 receptor and defines the specificity and efficiency of receptor-mediated phospholipase C-beta3 activationAntimetastatic activity of a cyclooxygenase-2 inhibitorProstaglandins and cancerExpression of cyclooxygenase-2, p53 and Ki-67 in gastric cancerRAS oncogenes: weaving a tumorigenic webOncogenic K-Ras regulates proliferation and cell junctions in lung epithelial cells through induction of cyclooxygenase-2 and activation of metalloproteinase-9The bitter barricading of prostaglandin biosynthesis pathway: understanding the molecular mechanism of selective cyclooxygenase-2 inhibition by amarogentin, a secoiridoid glycoside from Swertia chirayita.Identification of a novel ligand-receptor pair constitutively activated by ras oncogenesModulation of cell-substrate adhesion by arachidonic acid: lipoxygenase regulates cell spreading and ERK1/2-inducible cyclooxygenase regulates cell migration in NIH-3T3 fibroblasts.P53-mediated induction of Cox-2 counteracts p53- or genotoxic stress-induced apoptosisBarrett's-related esophageal adenocarcinoma: is chemoprevention a potential option?Posttranscriptional regulation of cyclooxygenase-2 in rat intestinal epithelial cells.Antitumor activity of the MEK inhibitor trametinib on intestinal polyp formation in Apc(Δ716) mice involves stromal COX-2.Frequent co-localization of Cox-2 and laminin-5 gamma2 chain at the invasive front of early-stage lung adenocarcinomas.Cyclooxygenase-2 expression and its association with thyroid lesionsReactive oxygen species and lung tumorigenesis by mutant K-ras: a working hypothesis.More than structural cells, fibroblasts create and orchestrate the tumor microenvironment.The role of apoptosis in therapy and prophylaxis of epithelial tumours by nonsteroidal anti-inflammatory drugs (NSAIDs).ERK-1/-2 and p38 kinase oppositely regulate 15-deoxy-delta(12,14)-prostaglandinJ(2)-Induced PPAR-gamma activation that mediates dedifferentiation but not cyclooxygenase-2 expression in articular chondrocytes.Protein kinase D mediates synergistic expression of COX-2 induced by TNF-{alpha} and bradykinin in human colonic myofibroblasts.Aspirin and colorectal cancer: back to the future.Chemoprevention in experimental animals.Emerging evidence of epithelial-to-mesenchymal transition in lung carcinogenesis.Endogenous and exogenous fibroblast growth factor 2 support survival of chick retinal neurons by control of neuronal neuronal bcl-x(L) and bcl-2 expression through a fibroblast berowth factor receptor 1- and ERK-dependent pathway.Mutant KRAS Enhances Tumor Cell Fitness by Upregulating Stress Granules.An Asp49 phospholipase A2 from snake venom induces cyclooxygenase-2 expression and prostaglandin E2 production via activation of NF-κB, p38MAPK, and PKC in macrophages.Induction of COX-2 by LPS in macrophages is regulated by Tpl2-dependent CREB activation signals.The aryl hydrocarbon receptor attenuates tobacco smoke-induced cyclooxygenase-2 and prostaglandin production in lung fibroblasts through regulation of the NF-kappaB family member RelB.PGE2 inhibits apoptosis in human adenocarcinoma Caco-2 cell line through Ras-PI3K association and cAMP-dependent kinase A activation.Oncogenic RAS mutations in myeloma cells selectively induce cox-2 expression, which participates in enhanced adhesion to fibronectin and chemoresistance.Differential regulation of cyclooxygenase-2 in nontransformed and ras-transformed intestinal epithelial cells.Salmonella enterica serovar Typhimurium infection induces cyclooxygenase 2 expression in macrophages: involvement of Salmonella pathogenicity island 2.PEA3 is up-regulated in response to Wnt1 and activates the expression of cyclooxygenase-2.The ERK MAP kinase pathway mediates induction of SGK (serum- and glucocorticoid-inducible kinase) by growth factors.Transforming growth factor-beta1 enhances Ha-ras-induced expression of cyclooxygenase-2 in intestinal epithelial cells via stabilization of mRNA.Synergistic induction of cyclooxygenase-2 by transforming growth factor-beta1 and epidermal growth factor inhibits apoptosis in epithelial cells.Combined inhibition of extracellular signal-regulated kinases and HSP90 sensitizes human colon carcinoma cells to ionizing radiation.Regulation and function of COX-2 gene expression in isolated gastric parietal cells.Post-translational regulation of COX2 activity by FYN in prostate cancer cells.Statins inhibit cyclooxygenase-2 and matrix metalloproteinase-9 in human endothelial cells: anti-angiogenic actions possibly contributing to plaque stability.
P2860
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P2860
Induction of cyclooxygenase-2 by activated Ha-ras oncogene in Rat-1 fibroblasts and the role of mitogen-activated protein kinase pathway
description
1998 nî lūn-bûn
@nan
1998 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Induction of cyclooxygenase-2 ...... tivated protein kinase pathway
@ast
Induction of cyclooxygenase-2 ...... tivated protein kinase pathway
@en
Induction of cyclooxygenase-2 ...... tivated protein kinase pathway
@nl
type
label
Induction of cyclooxygenase-2 ...... tivated protein kinase pathway
@ast
Induction of cyclooxygenase-2 ...... tivated protein kinase pathway
@en
Induction of cyclooxygenase-2 ...... tivated protein kinase pathway
@nl
prefLabel
Induction of cyclooxygenase-2 ...... tivated protein kinase pathway
@ast
Induction of cyclooxygenase-2 ...... tivated protein kinase pathway
@en
Induction of cyclooxygenase-2 ...... tivated protein kinase pathway
@nl
P2093
P2860
P356
P1476
Induction of cyclooxygenase-2 ...... tivated protein kinase pathway
@en
P2093
P2860
P304
22120-22127
P356
10.1074/JBC.273.34.22120
P407
P577
1998-08-01T00:00:00Z