The CYP2A3 gene product catalyzes coumarin 7-hydroxylation in human liver microsomes
about
Expression and alternative splicing of the cytochrome P-450 CYP2A7A genetic polymorphism in coumarin 7-hydroxylation: sequence of the human CYP2A genes and identification of variant CYP2A6 allelesPharmGKB summary: very important pharmacogene information for cytochrome P-450, family 2, subfamily A, polypeptide 6Genotyping of human cytochrome P450 2A6 (CYP2A6), a nicotine C-oxidasePolymorphisms of CYP2A6 and its practical consequencesFrequency of CYP2A6 gene deletion and its relation to risk of lung and esophageal cancer in the Chinese population.Analysis of coumarin 7-hydroxylation activity of cytochrome P450 2A6 using random mutagenesis.Predictors of Variation in CYP2A6 mRNA, Protein, and Enzyme Activity in a Human Liver Bank: Influence of Genetic and Nongenetic Factors.Five of 12 forms of vaccinia virus-expressed human hepatic cytochrome P450 metabolically activate aflatoxin B1Cigarette smoking.The role of CYP2B6 in human xenobiotic metabolism.Structural and functional studies of UDP-glucuronosyltransferases.Identification of human liver cytochrome P450 isoforms mediating omeprazole metabolismIdentification of human liver cytochrome P450 isoforms mediating secondary omeprazole metabolism.Diazepam metabolism by human liver microsomes is mediated by both S-mephenytoin hydroxylase and CYP3A isoforms.Human and mouse liver coumarin 7-hydroxylases do not metabolize warfarin in vitro.The role of pharmacogenetically-variable cytochrome P450 enzymes in drug abuse and dependence.Update information on human P450s.Genetic polymorphism of cytochrome P450 as a biomarker of susceptibility to environmental toxicity.12th meeting of the Scientific Group on Methodologies for the Safety Evaluation of Chemicals: susceptibility to environmental hazards.CYP2A13-catalysed coumarin metabolism: comparison with CYP2A5 and CYP2A6.The inhibition of CYP enzymes in mouse and human liver by pilocarpineHuman cytochromes P450: evolution and cDNA-directed expression.Genetic influences on smoking: candidate genes.Interindividual differences in nicotine metabolism and genetic polymorphisms of human CYP2A6.The contribution of common CYP2A6 alleles to variation in nicotine metabolism among European-AmericansOrphans in the human cytochrome P450 superfamily: approaches to discovering functions and relevance in pharmacology.Association of CYP2A6 deletion polymorphism with smoking habit and development of pulmonary emphysema.Competitive inhibition of coumarin 7-hydroxylation by pilocarpine and its interaction with mouse CYP 2A5 and human CYP 2A6CYP2A6 genetic variation and dexmedetomidine dispositionRegulation of cytochrome P450 gene expression in human colon and breast tumour xenograftsCYP2E1 active site residues in substrate recognition sequence 5 identified by photoaffinity labeling and homology modeling.Use of a predictive model derived from in vivo endophenotype measurements to demonstrate associations with a complex locus, CYP2A6.Cytochromes P-450 in rats: structures, functions, properties and relevant human forms.The human hepatic cytochromes P450 involved in drug metabolism.Hepatic CYP2A6 levels and nicotine metabolism: impact of genetic, physiological, environmental, and epigenetic factors.P450 and human cancer.Genetic variability in CYP2A6 and the pharmacokinetics of nicotine.Nicotine dependence pharmacogenetics: role of genetic variation in nicotine-metabolizing enzymesInter-individual Variability of Coumarin 7-hydroxylation (CYP2A6 activity) in an Iranian Population
P2860
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P2860
The CYP2A3 gene product catalyzes coumarin 7-hydroxylation in human liver microsomes
description
1990 nî lūn-bûn
@nan
1990 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1990 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1990年の論文
@ja
1990年論文
@yue
1990年論文
@zh-hant
1990年論文
@zh-hk
1990年論文
@zh-mo
1990年論文
@zh-tw
1990年论文
@wuu
name
The CYP2A3 gene product catalyzes coumarin 7-hydroxylation in human liver microsomes
@ast
The CYP2A3 gene product catalyzes coumarin 7-hydroxylation in human liver microsomes
@en
The CYP2A3 gene product catalyzes coumarin 7-hydroxylation in human liver microsomes
@nl
type
label
The CYP2A3 gene product catalyzes coumarin 7-hydroxylation in human liver microsomes
@ast
The CYP2A3 gene product catalyzes coumarin 7-hydroxylation in human liver microsomes
@en
The CYP2A3 gene product catalyzes coumarin 7-hydroxylation in human liver microsomes
@nl
prefLabel
The CYP2A3 gene product catalyzes coumarin 7-hydroxylation in human liver microsomes
@ast
The CYP2A3 gene product catalyzes coumarin 7-hydroxylation in human liver microsomes
@en
The CYP2A3 gene product catalyzes coumarin 7-hydroxylation in human liver microsomes
@nl
P2093
P356
P1433
P1476
The CYP2A3 gene product catalyzes coumarin 7-hydroxylation in human liver microsomes
@en
P2093
P304
P356
10.1021/BI00457A031
P407
P577
1990-02-06T00:00:00Z