Roles for proteolysis and trafficking in notch maturation and signal transduction
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Rel/NF-kappaB can trigger the Notch signaling pathway by inducing the expression of Jagged1, a ligand for Notch receptorsMammalian transcription factor ATF6 is synthesized as a transmembrane protein and activated by proteolysis in response to endoplasmic reticulum stressSKIP, a CBF1-associated protein, interacts with the ankyrin repeat domain of NotchIC To facilitate NotchIC functionIntegrity of intracellular domain of Notch ligand is indispensable for cleavage required for release of the Notch2 intracellular domain.A metalloprotease-disintegrin, MDC9/meltrin-gamma/ADAM9 and PKCdelta are involved in TPA-induced ectodomain shedding of membrane-anchored heparin-binding EGF-like growth factor.S phase-specific proteolytic cleavage is required to activate stable DNA binding by the CDP/Cut homeodomain proteinNotch signaling is essential for vascular morphogenesis in miceAn in vivo assay for the identification of target proteases which cleave membrane-associated substrates.Teneurin-1 is expressed in interconnected regions of the developing brain and is processed in vivoToll, a new piece in the puzzle of innate immunity.Activation of the Drosophila NF-kappaB factor Relish by rapid endoproteolytic cleavage.Notch3 pathway alterations in ovarian cancer.De novo transcriptome analysis of wing development-related signaling pathways in Locusta migratoria manilensis and Ostrinia furnacalis (Guenée)Periodic repression of Notch pathway genes governs the segmentation of Xenopus embryosSpecific knockdown of uPA/uPAR attenuates invasion in glioblastoma cells and xenografts by inhibition of cleavage and trafficking of Notch -1 receptorAberrant expression of Notch1/numb/snail signaling, an epithelial mesenchymal transition related pathway, in adenomyosis.Drosophila melanogaster auxilin regulates the internalization of Delta to control activity of the Notch signaling pathway.Phylogenetic footprinting analysis in the upstream regulatory regions of the Drosophila enhancer of split genes.Cathepsin S controls the trafficking and maturation of MHC class II molecules in dendritic cells.The N-terminal region of the CCAAT displacement protein (CDP)/Cux transcription factor functions as an autoinhibitory domain that modulates DNA binding.Identification of Notch1 as a frequent target for provirus insertional mutagenesis in T-cell lymphomas induced by leukemogenic mutants of mouse mammary tumor virus.Notch-1 activation by familial Alzheimer's disease (FAD)-linked mutant forms of presenilin-1.Murine leukemia provirus-mediated activation of the Notch1 gene leads to induction of HES-1 in a mouse T lymphoma cell line, DL-3.Fbxw7-dependent degradation of Notch is required for control of "stemness" and neuronal-glial differentiation in neural stem cells.Biochemical and pharmacological criteria define two shedding activities for TRANCE/OPGL that are distinct from the tumor necrosis factor alpha convertase.Widespread production of novel soluble protein isoforms by alternative splicing removal of transmembrane anchoring domains.Pre-NOTCH Expression and ProcessingPre-NOTCH Processing in GolgiNotch1 and Jagged1 expression by the developing pulmonary vasculature.NOTCH precursor cleaved to form mature NOTCHThe pattern of expression of Notch protein members in normal and pathological endometrium.
P2860
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P2860
Roles for proteolysis and trafficking in notch maturation and signal transduction
description
1998 nî lūn-bûn
@nan
1998 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Roles for proteolysis and trafficking in notch maturation and signal transduction
@ast
Roles for proteolysis and trafficking in notch maturation and signal transduction
@en
Roles for proteolysis and trafficking in notch maturation and signal transduction
@nl
type
label
Roles for proteolysis and trafficking in notch maturation and signal transduction
@ast
Roles for proteolysis and trafficking in notch maturation and signal transduction
@en
Roles for proteolysis and trafficking in notch maturation and signal transduction
@nl
prefLabel
Roles for proteolysis and trafficking in notch maturation and signal transduction
@ast
Roles for proteolysis and trafficking in notch maturation and signal transduction
@en
Roles for proteolysis and trafficking in notch maturation and signal transduction
@nl
P1433
P1476
Roles for proteolysis and trafficking in notch maturation and signal transduction
@en
P2093
P356
10.1016/S0092-8674(00)81583-4
P407
P577
1998-08-21T00:00:00Z