Concerted action of poly(A) nucleases and decapping enzyme in mammalian mRNA turnover
about
Let-7b/c enhance the stability of a tissue-specific mRNA during mammalian organogenesis as part of a feedback loop involving KSRPAnti-proliferative protein Tob negatively regulates CPEB3 target by recruiting Caf1 deadenylaseHuman Ccr4-Not complex is a ligand-dependent repressor of nuclear receptor-mediated transcriptionCCR4-NOT deadenylates mRNA associated with RNA-induced silencing complexes in human cellsThe structural basis for the interaction between the CAF1 nuclease and the NOT1 scaffold of the human CCR4-NOT deadenylase complexDepletion of mammalian CCR4b deadenylase triggers elevation of the p27Kip1 mRNA level and impairs cell growthC2ORF29/CNOT11 and CNOT10 form a new module of the CCR4-NOT complexThe anti-proliferative activity of BTG/TOB proteins is mediated via the Caf1a (CNOT7) and Caf1b (CNOT8) deadenylase subunits of the Ccr4-not complexMultiple mRNA decapping enzymes in mammalian cellsNOT10 and C2orf29/NOT11 form a conserved module of the CCR4-NOT complex that docks onto the NOT1 N-terminal domainPhosphorylation at intrinsically disordered regions of PAM2 motif-containing proteins modulates their interactions with PABPC1 and influences mRNA fateMammalian miRNA RISC recruits CAF1 and PABP to affect PABP-dependent deadenylationThe BTG2 protein is a general activator of mRNA deadenylationPoly(A) nuclease interacts with the C-terminal domain of polyadenylate-binding protein domain from poly(A)-binding proteinThe Ccr4-NOT deadenylase subunits CNOT7 and CNOT8 have overlapping roles and modulate cell proliferationUpf1 phosphorylation triggers translational repression during nonsense-mediated mRNA decayThe Ccr4a (CNOT6) and Ccr4b (CNOT6L) deadenylase subunits of the human Ccr4-Not complex contribute to the prevention of cell death and senescenceQuantitative characterization of Tob interactions provides the thermodynamic basis for translation termination-coupled deadenylase regulationAn unconventional human Ccr4-Caf1 deadenylase complex in nuclear cajal bodiesInvolvement of the SMRT/NCoR-HDAC3 complex in transcriptional repression by the CNOT2 subunit of the human Ccr4-Not complexNot1 mediates recruitment of the deadenylase Caf1 to mRNAs targeted for degradation by tristetraprolinHuman Ccr4-Not complexes contain variable deadenylase subunitsYeast transcripts cleaved by an internal ribozyme provide new insight into the role of the cap and poly(A) tail in translation and mRNA decayTethering KSRP, a decay-promoting AU-rich element-binding protein, to mRNAs elicits mRNA decayThe roles of TTP and BRF proteins in regulated mRNA decayNew ways to meet your (3') end oligouridylation as a step on the path to destructionMechanism of mRNA deadenylation: evidence for a molecular interplay between translation termination factor eRF3 and mRNA deadenylasesHuman TOB, an antiproliferative transcription factor, is a poly(A)-binding protein-dependent positive regulator of cytoplasmic mRNA deadenylationThe organization and regulation of mRNA-protein complexesVirus-derived small RNAs: molecular footprints of host-pathogen interactionsCcr4-Not complex: the control freak of eukaryotic cellsThe long and the short of it: the role of the zinc finger polyadenosine RNA binding protein, Nab2, in control of poly(A) tail lengthMechanisms of deadenylation-dependent decayRecombinant messenger RNA technology and its application in cancer immunotherapy, transcript replacement therapies, pluripotent stem cell induction, and beyondProteins involved in the degradation of cytoplasmic mRNA in the major eukaryotic model systemsThe panorama of miRNA-mediated mechanisms in mammalian cellsThe role of mammalian poly(A)-binding proteins in co-ordinating mRNA turnoverHeterogeneity and complexity within the nuclease module of the Ccr4-Not complexPost-transcriptional Control of Tumor Cell Autonomous Metastatic Potential by CCR4-NOT Deadenylase CNOT7Two distinct cytokinesis pathways drive trypanosome cell division initiation from opposite cell ends.
P2860
Q21563369-8844CCB1-FBCE-4F0B-BBBC-7F0F15899A18Q24293599-FA0E0907-8FE9-4E70-83C9-3D3A375E7583Q24293751-458DD51B-A0E5-4BF7-8440-34B4239CE782Q24294694-B432B1F4-FB66-4195-B7E0-86CDC8A62A17Q24298677-F3FD7FF4-0500-4640-9284-1F36E18711E5Q24303821-158E0E2E-2DF6-4963-8545-2645A816AEF3Q24305555-4E71AFA3-2D0F-44FB-9D36-D48F927AE816Q24306032-B432B625-C5BA-466B-8497-1A4061907361Q24306739-DCD3478C-23EE-45B8-A3C3-1CC382A2B355Q24307925-D47420CA-F602-4B66-BD49-959B4CC172CAQ24310482-B48F43DF-EF29-444C-9AE7-5642D407F9F3Q24310618-C11DBCB2-C67F-4613-BDD1-D69CB38250ADQ24310741-8EAD6E27-483F-4F1C-ABB4-55375841923CQ24314646-3208D1E8-7047-48B0-842F-D912B4CDE611Q24314993-168E006D-8726-4CC2-A14D-2B3CD2F6A90AQ24323275-DFCF11CE-2239-4B49-A4A8-3E2201FFD3A9Q24336953-A7015785-AACB-4B40-AD28-00EDA3F12BAEQ24337126-82C7CB9B-D6E5-478B-B59D-7E2FC7A21FE9Q24337378-406BB2D4-219A-4356-9502-9683F55B2C11Q24337385-85DB1450-1D8C-4E6D-9770-94381365B69AQ24338694-F201318E-3E74-4CCA-AFF8-2E2160F561F9Q24339449-83BFDE7D-B3F1-49EC-A68E-220DBB3539A7Q24548790-71704D4B-3000-4AA8-8D8A-8089ACADD826Q24548948-EDD4620D-90B9-4322-B922-8D55D65FBE0DQ24633013-7F8E85CF-AB24-4822-B235-6DCA6E7F8585Q24647486-E2A6A0EB-814D-4846-9BF3-FB05070342C5Q24675982-58114CB7-B188-4182-AEB1-FB3414B9753FQ24681334-2179EA7D-672E-4428-AC0D-254085FE8359Q26744258-A6C7925B-DC7A-4B16-A6A1-C85E5A074240Q26750532-CFB0B9C3-AE1C-4EAD-AA7C-B87C24358FECQ26823940-7F6AAC3A-8A21-48DB-B61F-E52AA17CD0E9Q26825398-B9C46577-4670-4843-A818-9180BD3356C4Q26829435-05B9F3BE-74CF-4D97-B437-B5BC24FD31DEQ26861563-1335BA35-C738-4F0D-A6B1-0F1179CCD8F5Q26864165-145F2616-40BC-450A-8A64-863674BAED41Q27001268-7306A05B-1680-4826-9337-6C3DF0EA31F0Q27010244-AA3D7139-6143-44BE-AC5D-60EA4AF9D39FQ27023667-01C52CCC-7E43-44C9-B5D8-7077C3FA2FD1Q27309177-7A1D86C5-9B01-4281-B9CE-5F0DACD41D04Q27316118-6A6E421F-6252-4B98-AB91-1538F51A5D05
P2860
Concerted action of poly(A) nucleases and decapping enzyme in mammalian mRNA turnover
description
2005 nî lūn-bûn
@nan
2005 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Concerted action of poly(A) nucleases and decapping enzyme in mammalian mRNA turnover
@ast
Concerted action of poly(A) nucleases and decapping enzyme in mammalian mRNA turnover
@en
Concerted action of poly(A) nucleases and decapping enzyme in mammalian mRNA turnover
@nl
type
label
Concerted action of poly(A) nucleases and decapping enzyme in mammalian mRNA turnover
@ast
Concerted action of poly(A) nucleases and decapping enzyme in mammalian mRNA turnover
@en
Concerted action of poly(A) nucleases and decapping enzyme in mammalian mRNA turnover
@nl
prefLabel
Concerted action of poly(A) nucleases and decapping enzyme in mammalian mRNA turnover
@ast
Concerted action of poly(A) nucleases and decapping enzyme in mammalian mRNA turnover
@en
Concerted action of poly(A) nucleases and decapping enzyme in mammalian mRNA turnover
@nl
P2093
P2860
P3181
P356
P1476
Concerted action of poly(A) nucleases and decapping enzyme in mammalian mRNA turnover
@en
P2093
Akio Yamashita
Ann-Bin Shyu
Chyi-Ying A Chen
Tsung-Cheng Chang
Wenmiao Zhu
Yukiko Yamashita
Zhenping Zhong
P2860
P2888
P304
P3181
P356
10.1038/NSMB1016
P407
P577
2005-12-01T00:00:00Z