Targeted disruption of the biglycan gene leads to an osteoporosis-like phenotype in mice - Wikidata - wikimedia - TriplyDB

Targeted disruption of the biglycan gene leads to an osteoporosis-like phenotype in mice

Targeted disruption of the biglycan gene leads to an osteoporosis-like phenotype in mice

http://www.wikidata.org/entity/Q28281780

about

Defects in tendon, ligament, and enthesis in response to genetic alterations in key proteoglycans and glycoproteins: a review Proteoglycan form and function: A comprehensive nomenclature of proteoglycans The novel small leucine-rich protein chondroadherin-like (CHADL) is expressed in cartilage and modulates chondrocyte differentiation Biglycan is a new extracellular component of the Chordin-BMP4 signaling pathway Biglycan binds to alpha- and gamma-sarcoglycan and regulates their expression during development The small leucine-rich repeat proteoglycan biglycan binds to alpha-dystroglycan and is upregulated in dystrophic muscle Articular cartilage and changes in arthritis: noncollagenous proteins and proteoglycans in the extracellular matrix of cartilage Short and tall stature: a new paradigm emerges The biology of small leucine-rich proteoglycans in bone pathophysiology Bone composition: relationship to bone fragility and antiosteoporotic drug effects Bone health and associated metabolic complications in neuromuscular diseases Insights into the key roles of proteoglycans in breast cancer biology and translational medicine Expression pattern and gene characterization of asporin. a newly discovered member of the leucine-rich repeat protein family Molecular interactions of biglycan and decorin with elastic fiber components: biglycan forms a ternary complex with tropoelastin and microfibril-associated glycoprotein 1 Bone morphogenetic protein-1/Tolloid-like proteinases process dentin matrix protein-1 Vibrational spectroscopic imaging for the evaluation of matrix and mineral chemistry Infrared imaging microscopy of bone: illustrations from a mouse model of Fabry disease Immunolocalization of proteoglycans in Meckel's cartilage of the rat The skeletal phenotype of chondroadherin deficient mice Contribution of extracellular matrix to the mechanical properties of the heart Biglycan and decorin bind close to the n-terminal region of the collagen VI triple helix.Finding genes in the C2C12 osteogenic pathway by k-nearest-neighbor classification of expression data.Biglycan and fibromodulin have essential roles in regulating chondrogenesis and extracellular matrix turnover in temporomandibular joint osteoarthritis.Biglycan and decorin differentially regulate signaling in the fetal membranes Interclass small leucine-rich repeat proteoglycan interactions regulate collagen fibrillogenesis and corneal stromal assembly.Key roles for the small leucine-rich proteoglycans in renal and pulmonary pathophysiology Inbred strain-specific effects of exercise in wild type and biglycan deficient mice.Increased C-telopeptide cross-linking of tendon type I collagen in fibromodulin-deficient mice.Pathophysiological Significance of Dermatan Sulfate Proteoglycans Revealed by Human Genetic Disorders.Exclusion of biglycan mutations in a cohort of patients with neuromuscular disorders.Thrombospondin-2 facilitates assembly of a type-I collagen-rich matrix in marrow stromal cells undergoing osteoblastic differentiation.The matrix component biglycan is proinflammatory and signals through Toll-like receptors 4 and 2 in macrophages Hydrolyzed eggshell membrane immobilized on phosphorylcholine polymer supplies extracellular matrix environment for human dermal fibroblasts.Bone morphogenetic protein-1 processes probiglycan.Fibromodulin and Biglycan Modulate Periodontium through TGFβ/BMP Signaling.Loss of dermatan-4-sulfotransferase 1 function results in adducted thumb-clubfoot syndrome.Uterine dysfunction in biglycan and decorin deficient mice leads to dystocia during parturition.Osteoadherin accumulates in the predentin towards the mineralization front in the developing tooth.Biglycan deficiency: increased aortic aneurysm formation and lack of atheroprotection.Extracellular microfibrils control osteoblast-supported osteoclastogenesis by restricting TGF{beta} stimulation of RANKL production

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P2860

Targeted disruption of the biglycan gene leads to an osteoporosis-like phenotype in mice

http://www.wikidata.org/entity/Q28281780

description

1998 nî lūn-bûn

@nan

1998 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

1998 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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1998年の論文

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1998年論文

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1998年論文

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1998年論文

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1998年論文

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1998年論文

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1998年论文

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name

Targeted disruption of the biglycan gene leads to an osteoporosis-like phenotype in mice

@ast

Targeted disruption of the biglycan gene leads to an osteoporosis-like phenotype in mice

@en

Targeted disruption of the biglycan gene leads to an osteoporosis-like phenotype in mice

@nl

type

label

Targeted disruption of the biglycan gene leads to an osteoporosis-like phenotype in mice

@ast

Targeted disruption of the biglycan gene leads to an osteoporosis-like phenotype in mice

@en

Targeted disruption of the biglycan gene leads to an osteoporosis-like phenotype in mice

@nl

prefLabel

Targeted disruption of the biglycan gene leads to an osteoporosis-like phenotype in mice

@ast

Targeted disruption of the biglycan gene leads to an osteoporosis-like phenotype in mice

@en

Targeted disruption of the biglycan gene leads to an osteoporosis-like phenotype in mice

@nl

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Targeted disruption of the biglycan gene leads to an osteoporosis-like phenotype in mice

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Bianco P

http://www.w3.org/2001/XMLSchema#string

Bonadio J

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Fisher LW

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Goldstein S

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Kulkarni AB

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Longenecker G

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Robey PG

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Satomura K

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Smith E

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Sommer B

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2325352

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10.1038/1746

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1

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20

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Adele L. Boskey

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Pedro Domínguez

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9731537

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