Mildronate, an inhibitor of carnitine biosynthesis, induces an increase in gamma-butyrobetaine contents and cardioprotection in isolated rat heart infarction

Mildronate, an inhibitor of carnitine biosynthesis, induces an increase in gamma-butyrobetaine contents and cardioprotection in isolated rat heart infarction

Item
http://www.wikidata.org/entity/Q28281960
Development and application of a fluoride-detection-based fluorescence assay for γ-butyrobetaine hydroxylaseA photoreactive small-molecule probe for 2-oxoglutarate oxygenases.The cardioprotective effect of mildronate is diminished after co-treatment with L-carnitine.Efficacy and safety of mildronate for acute ischemic stroke: a randomized, double-blind, active-controlled phase II multicenter trial.Protective effects of mildronate in an experimental model of type 2 diabetes in Goto-Kakizaki rats.Metabolic therapy for the treatment of ischemic heart disease: reality and expectations.Muscle carnitine availability plays a central role in regulating fuel metabolism in the rodent.Inhibition of L-carnitine biosynthesis and transport by methyl-γ-butyrobetaine decreases fatty acid oxidation and protects against myocardial infarction.Modulating carnitine levels by targeting its biosynthesis pathway - selective inhibition of γ-butyrobetaine hydroxylase.Inhibition of carnitine acetyltransferase by mildronate, a regulator of energy metabolism.Human carnitine biosynthesis proceeds via (2S,3S)-3-hydroxy-Nε-trimethyllysine.Meldonium decreases the diet-increased plasma levels of trimethylamine N-oxide, a metabolite associated with atherosclerosis.Mildronate treatment alters γ-butyrobetaine and l-carnitine concentrations in healthy volunteers.Microencapsulation of mildronate in biodegradable and non-biodegradable polymers.Inhibited Carnitine Synthesis Causes Systemic Alteration of Nutrient Metabolism in Zebrafish.
P2860

Mildronate, an inhibitor of carnitine biosynthesis, induces an increase in gamma-butyrobetaine contents and cardioprotection in isolated rat heart infarction

Item
http://www.wikidata.org/entity/Q28281960
description
2006 nî lūn-bûn
@nan
2006 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Mildronate, an inhibitor of ca ...... isolated rat heart infarction
@ast
Mildronate, an inhibitor of ca ...... isolated rat heart infarction
@en
Mildronate, an inhibitor of ca ...... isolated rat heart infarction
@nl
type
label
Mildronate, an inhibitor of ca ...... isolated rat heart infarction
@ast
Mildronate, an inhibitor of ca ...... isolated rat heart infarction
@en
Mildronate, an inhibitor of ca ...... isolated rat heart infarction
@nl
prefLabel
Mildronate, an inhibitor of ca ...... isolated rat heart infarction
@ast
Mildronate, an inhibitor of ca ...... isolated rat heart infarction
@en
Mildronate, an inhibitor of ca ...... isolated rat heart infarction
@nl
P1433
P1476
P2093
P304
P31
P356
P407
P433
P478
P577
P698
P356
P1433
P1476
Mildronate, an inhibitor of ca ...... isolated rat heart infarction
@en
P2093
P304
P31
P356
10.1097/01.FJC.0000250077.07702.23
P407
P433
P478
P577
P698