The HIV nef protein associates with protein kinase C theta - Wikidata - wikimedia - TriplyDB

The HIV nef protein associates with protein kinase C theta

The HIV nef protein associates with protein kinase C theta

http://www.wikidata.org/entity/Q28282007

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Direct interaction in T-cells between thetaPKC and the tyrosine kinase p59fyn Mechanism for down-regulation of CD28 by Nef.Binding of c-Raf1 kinase to a conserved acidic sequence within the carboxyl-terminal region of the HIV-1 Nef protein Myristoyl moiety of HIV Nef is involved in regulation of the interaction with calmodulin in vivo Activation of the PAK-related kinase by human immunodeficiency virus type 1 Nef in primary human peripheral blood lymphocytes and macrophages leads to phosphorylation of a PIX-p95 complex The Nef protein of HIV-1 associates with rafts and primes T cells for activation Borna disease virus blocks potentiation of presynaptic activity through inhibition of protein kinase C signaling.PKC-Theta in Regulatory and Effector T-cell Functions Caspase-3-mediated cleavage of protein kinase C theta in induction of apoptosis A protein kinase Cdelta-binding protein SRBC whose expression is induced by serum starvation The pathogenicity of human immunodeficiency virus (HIV) type 1 Nef in CD4C/HIV transgenic mice is abolished by mutation of its SH3-binding domain, and disease development is delayed in the absence of Hck.Activation of NFAT-dependent gene expression by Nef: conservation among divergent Nef alleles, dependence on SH3 binding and membrane association, and cooperation with protein kinase C-theta Zeta chain of the T-cell receptor interacts with nef of simian immunodeficiency virus and human immunodeficiency virus type 2 Simian immunodeficiency virus Nef protein delays the progression of CD4+ T cells through G1/S phase of the cell cycle.The therapeutic potential of adenosine triphosphate as an immune modulator in the treatment of HIV/AIDS: a combination approach with HAART.Immune selection in vitro reveals human immunodeficiency virus type 1 Nef sequence motifs important for its immune evasion function in vivo.14-3-3s are potential biomarkers for HIV-related neurodegeneration.Impact of Nef-mediated downregulation of major histocompatibility complex class I on immune response to simian immunodeficiency virus.Inhibition of Kaposi's sarcoma-associated herpesvirus lytic replication by HIV-1 Nef and cellular microRNA hsa-miR-1258.The T-cell receptor zeta chain contains two homologous domains with which simian immunodeficiency virus Nef interacts and mediates down-modulation.The NTPase/helicase domain of hepatitis C virus nonstructural protein 3 inhibits protein kinase C independently of its NTPase activity.Mutational analysis of human immunodeficiency virus type 1 (HIV-1) accessory genes: requirement of a site in the nef gene for HIV-1 replication in activated CD4+ T cells in vitro and in vivo.Regulation of human immunodeficiency virus type 1 infectivity by the ERK mitogen-activated protein kinase signaling pathway.Nef-mediated resistance of human immunodeficiency virus type 1 to antiviral cytotoxic T lymphocytes.Simultaneous assessment of CD4 and MHC-I downregulation by Nef primary isolates in the context of infection.Deletion of nef slows but does not prevent CD4-positive T-cell depletion in human immunodeficiency virus type 1-infected human-PBL-SCID mice.Activation of the T-cell receptor signaling pathway by Nef from an aggressive strain of simian immunodeficiency virus.Mechanisms of HIV receptor and co-receptor down-regulation by prostratin: role of conventional and novel PKC isoforms.Down-modulation of TCR/CD3 surface complexes after HIV-1 infection is associated with differential expression of the viral regulatory genes.T-Cell Signaling in HIV-1 Infection.PKC-theta-mediated signal delivery from the TCR/CD28 surface receptors.Impaired protein kinase C activation/translocation in Epstein-Barr virus-infected monocytes.Uncoupling activation-induced modulation of CD16 and CD69 in CD56+ cells during AIDS.Hyper-responsiveness to stimulation of human immunodeficiency virus-infected CD4+ T cells requires Nef and Tat virus gene products and results from higher NFAT, NF-kappaB, and AP-1 induction.Protein Kinase C-mediated Phosphorylation of HIV-I Nef in Human Cell Lines

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P2860

The HIV nef protein associates with protein kinase C theta

http://www.wikidata.org/entity/Q28282007

description

1996 nî lūn-bûn

@nan

1996 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

1996 թվականի հուլիսին հրատարակված գիտական հոդված

@hy

1996年の論文

@ja

1996年論文

@yue

1996年論文

@zh-hant

1996年論文

@zh-hk

1996年論文

@zh-mo

1996年論文

@zh-tw

1996年论文

@wuu

name

The HIV nef protein associates with protein kinase C theta

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The HIV nef protein associates with protein kinase C theta

@en

The HIV nef protein associates with protein kinase C theta

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type

label

The HIV nef protein associates with protein kinase C theta

@ast

The HIV nef protein associates with protein kinase C theta

@en

The HIV nef protein associates with protein kinase C theta

@nl

prefLabel

The HIV nef protein associates with protein kinase C theta

@ast

The HIV nef protein associates with protein kinase C theta

@en

The HIV nef protein associates with protein kinase C theta

@nl

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P2860

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P356

JBC.271.28.16753

P1433

Journal of Biological Chemistry

P1476

The HIV nef protein associates with protein kinase C theta

@en

P2093

B L Smith

http://www.w3.org/2001/XMLSchema#string

B W Krushelnycky

http://www.w3.org/2001/XMLSchema#string

D Mochly-Rosen

http://www.w3.org/2001/XMLSchema#string

P Berg

http://www.w3.org/2001/XMLSchema#string

P2860

Serine phosphorylation-independent downregulation of cell-surface CD4 by nef

Molecular cloning and characterization of PKC theta, a novel member of the protein kinase C (PKC) gene family expressed predominantly in hematopoietic cells

Nef induces CD4 endocytosis: requirement for a critical dileucine motif in the membrane-proximal CD4 cytoplasmic domain

Cloning of an intracellular receptor for protein kinase C: a homolog of the beta subunit of G proteins

Human immunodeficiency virus type 1 Nef associates with a cellular serine kinase in T lymphocytes

Protein kinase C--a question of specificity

Localization of protein kinases by anchoring proteins: a theme in signal transduction

Identification of intracellular receptor proteins for activated protein kinase C.

Expression of the type 1 human immunodeficiency virus Nef protein in T cells prevents antigen receptor-mediated induction of interleukin 2 mRNA.

HIV-1 Nef protein inhibits the recruitment of AP-1 DNA-binding activity in human T-cells.

P304

16753-7

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scholarly article

P356

10.1074/JBC.271.28.16753

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P407

P433

28

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P478

271

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P577

1996-07-12T00:00:00Z

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P698

8663223

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