Dosage-dependent tumor suppression by histone deacetylases 1 and 2 through regulation of c-Myc collaborating genes and p53 function - Wikidata - wikimedia - TriplyDB

Dosage-dependent tumor suppression by histone deacetylases 1 and 2 through regulation of c-Myc collaborating genes and p53 function

Dosage-dependent tumor suppression by histone deacetylases 1 and 2 through regulation of c-Myc collaborating genes and p53 function

http://www.wikidata.org/entity/Q28283633

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Combating the epigenome: epigenetic drugs against non-Hodgkin's lymphoma New and emerging HDAC inhibitors for cancer treatment Mutations of Chromatin Structure Regulating Genes in Human Malignancies.The therapeutic potential of class I selective histone deacetylase inhibitors in ovarian cancer Sin3a-associated Hdac1 and Hdac2 are essential for hematopoietic stem cell homeostasis and contribute differentially to hematopoiesis.Histone deacetylase 2 and N-Myc reduce p53 protein phosphorylation at serine 46 by repressing gene transcription of tumor protein 53-induced nuclear protein 1 HDAC1 controls CD8+ T cell homeostasis and antiviral response.Gut microbiota in hypertension.Histone Deacetylase 3 Is Required for Efficient T Cell Development.USP4 inhibits p53 and NF-κB through deubiquitinating and stabilizing HDAC2.HDAC1 and HDAC2 in mouse oocytes and preimplantation embryos: Specificity versus compensation.Lentivirus-mediated Knockdown of HDAC1 Uncovers Its Role in Esophageal Cancer Metastasis and Chemosensitivity.Histone deacetylase 1 plays a predominant pro-oncogenic role in Eμ-myc driven B cell lymphoma Transcription and beyond: the role of mammalian class I lysine deacetylases Towards selective inhibition of histone deacetylase isoforms: what has been achieved, where we are and what will be next.Class I HDACs Affect DNA Replication, Repair, and Chromatin Structure: Implications for Cancer Therapy.Histone deacetylases and their inhibitors in cancer, neurological diseases and immune disorders.Histone deacetylases 1 and 2 regulate DNA replication and DNA repair: potential targets for genome stability-mechanism-based therapeutics for a subset of cancers.Histone deacetylase inhibitors and epigenetic regulation in lymphoid malignancies.Divergent roles of HDAC1 and HDAC2 in the regulation of epidermal development and tumorigenesis.A single allele of Hdac2 but not Hdac1 is sufficient for normal mouse brain development in the absence of its paralog.Knockdown of HDAC1 expression suppresses invasion and induces apoptosis in glioma cells HDAC10 as a potential therapeutic target in ovarian cancer.Metal-dependent Deacetylases: Cancer and Epigenetic Regulators An overview of investigational Histone deacetylase inhibitors (HDACis) for the treatment of non-Hodgkin's lymphoma.Epigenetic regulation of Smad2 and Smad3 by profilin-2 promotes lung cancer growth and metastasis.HDAC1 inhibition by melatonin leads to suppression of lung adenocarcinoma cells via induction of oxidative stress and activation of apoptotic pathways.The transcriptional repressor HDAC7 promotes apoptosis and c-Myc downregulation in particular types of leukemia and lymphoma.A common strategy for initiating the transition from proliferation to quiescence.A role for paralog-specific sumoylation in histone deacetylase 1 stability.A chemical probe toolbox for dissecting the cancer epigenome.Dynamic phosphorylation of Histone Deacetylase 1 by Aurora kinases during mitosis regulates zebrafish embryos development.Primary Pediatric Hypertension: Current Understanding and Emerging Concepts.Novel recurrent chromosomal aberrations detected in clonal plasma cells of light chain amyloidosis patients show potential adverse prognostic effect: first results from a genome-wide copy number array analysis.HDAC5 promotes colorectal cancer cell proliferation by up-regulating DLL4 expression Oxidative stress signaling to chromatin in health and disease.Divergent JNK Phosphorylation of HDAC3 in Triple-Negative Breast Cancer Cells Determines HDAC Inhibitor Binding and Selectivity.Acetylation and deacetylation in cancer stem-like cells.Mbd3/NuRD controls lymphoid cell fate and inhibits tumorigenesis by repressing a B cell transcriptional program.4-Phenybutyric acid promotes gastric cancer cell migration via histone deacetylase inhibition-mediated HER3/HER4 up-regulation.

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Dosage-dependent tumor suppression by histone deacetylases 1 and 2 through regulation of c-Myc collaborating genes and p53 function

http://www.wikidata.org/entity/Q28283633

description

2013 nî lūn-bûn

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2013 թուականի Մարտին հրատարակուած գիտական յօդուած

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2013 թվականի մարտին հրատարակված գիտական հոդված

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2013年の論文

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2013年論文

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2013年論文

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2013年論文

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2013年论文

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name

Dosage-dependent tumor suppres ...... orating genes and p53 function

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Dosage-dependent tumor suppres ...... orating genes and p53 function

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Dosage-dependent tumor suppres ...... orating genes and p53 function

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type

label

Dosage-dependent tumor suppres ...... orating genes and p53 function

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Dosage-dependent tumor suppres ...... orating genes and p53 function

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Dosage-dependent tumor suppres ...... orating genes and p53 function

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prefLabel

Dosage-dependent tumor suppres ...... orating genes and p53 function

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Dosage-dependent tumor suppres ...... orating genes and p53 function

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Dosage-dependent tumor suppres ...... orating genes and p53 function

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BLOOD-2012-08-450916

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Dosage-dependent tumor suppres ...... orating genes and p53 function

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Eva Yanover

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Jan-Hermen Dannenberg

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Lodewyk F Wessels

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Marinus R Heideman

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Roel H Wilting

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Ron M Kerkhoven

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P2860

Hallmarks of Cancer: The Next Generation

SIRT2 maintains genome integrity and suppresses tumorigenesis through regulating APC/C activity

DYRK1A and DYRK3 promote cell survival through phosphorylation and activation of SIRT1

Hdac1 and Hdac2 act redundantly to control p63 and p53 functions in epidermal progenitor cells

HDAC2 negatively regulates memory formation and synaptic plasticity.

Insertional mutagenesis reveals progression genes and checkpoints in MYC/Runx2 lymphomas

DNMT3A Mutations in Acute Myeloid Leukemia

Somatic mutations of the histone methyltransferase gene EZH2 in myelodysplastic syndromes.

Deacetylation of p53 modulates its effect on cell growth and apoptosis

Jdp2 downregulates Trp53 transcription to promote leukaemogenesis in the context of Trp53 heterozygosity

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2038-2050

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10.1182/BLOOD-2012-08-450916

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