Genomic structure of an attenuated quasi species of HIV-1 from a blood transfusion donor and recipients
about
Ability of HIV-1 Nef to downregulate CD4 and HLA class I differs among viral subtypesThe spread, treatment, and prevention of HIV-1: evolution of a global pandemicNegative factor from SIV binds to the catalytic subunit of the V-ATPase to internalize CD4 and to increase viral infectivityMechanism for down-regulation of CD28 by Nef.Human immunodeficiency virus type 1 Nef binds to tumor suppressor p53 and protects cells against p53-mediated apoptosis.Subunit H of the V-ATPase binds to the medium chain of adaptor protein complex 2 and connects Nef to the endocytic machineryHuman immunodeficiency virus type 1 Nef binds directly to Lck and mitogen-activated protein kinase, inhibiting kinase activityBinding of HIV-1 Nef to a novel thioesterase enzyme correlates with Nef-mediated CD4 down-regulationBinding of c-Raf1 kinase to a conserved acidic sequence within the carboxyl-terminal region of the HIV-1 Nef proteinMyristoyl moiety of HIV Nef is involved in regulation of the interaction with calmodulin in vivoSERINC3 and SERINC5 restrict HIV-1 infectivity and are counteracted by NefHIV-1 Nef promotes infection by excluding SERINC5 from virion incorporationStrong human immunodeficiency virus (HIV)-specific cytotoxic T-lymphocyte activity in Sydney Blood Bank Cohort patients infected with nef-defective HIV type 1Characterization of three nef-defective human immunodeficiency virus type 1 strains associated with long-term nonprogression. Australian Long-Term Nonprogressor Study Group.Activation of the PAK-related kinase by human immunodeficiency virus type 1 Nef in primary human peripheral blood lymphocytes and macrophages leads to phosphorylation of a PIX-p95 complexSeparable functions of Nef disrupt two aspects of T cell receptor machinery: CD4 expression and CD3 signalingCo-localization of HIV-1 Nef with the AP-2 adaptor protein complex correlates with Nef-induced CD4 down-regulationMechanism of Nef-induced CD4 endocytosis: Nef connects CD4 with the mu chain of adaptor complexes.Contribution of immune activation to the pathogenesis and transmission of human immunodeficiency virus type 1 infectionLeucine-specific, functional interactions between human immunodeficiency virus type 1 Nef and adaptor protein complexesPositive selection of HIV-1 cytotoxic T lymphocyte escape variants during primary infectionHIV-1 Nef disrupts intracellular trafficking of major histocompatibility complex class I, CD4, CD8, and CD28 by distinct pathways that share common elementsThe Nef protein of HIV-1 associates with rafts and primes T cells for activationThe Nef protein of human immunodeficiency virus type 1 enhances serine phosphorylation of the viral matrixVpr R77Q is associated with long-term nonprogressive HIV infection and impaired induction of apoptosisInduction of Fas ligand expression by HIV involves the interaction of Nef with the T cell receptor zeta chainHLA B*5701 is highly associated with restriction of virus replication in a subgroup of HIV-infected long term nonprogressorsInterleukin 10 is induced by recombinant HIV-1 Nef protein involving the calcium/calmodulin-dependent phosphodiesterase signal transduction pathwayThe association of Nef with a cellular serine/threonine kinase and its enhancement of infectivity are viral isolate dependentHuman immunodeficiency virus type 1 Nef associates with a member of the p21-activated kinase familyInteraction of HIV-1 Nef with the cellular dileucine-based sorting pathway is required for CD4 down-regulation and optimal viral infectivityHIV-1 can escape from RNA interference by evolving an alternative structure in its RNA genomeRole of viral evolutionary rate in HIV-1 disease progression in a linked cohortRemodeling of the Host Cell Plasma Membrane by HIV-1 Nef and Vpu: A Strategy to Ensure Viral Fitness and PersistenceStudies of retroviral infection in humanized miceSmall molecule inhibitors of the HIV-1 virulence factor, NefExosomes are unlikely involved in intercellular Nef transferDefinition of the stage of host cell genetic restriction of replication of human immunodeficiency virus type 1 in monocytes and monocyte-derived macrophages by using twins.Twin studies demonstrate a host cell genetic effect on productive human immunodeficiency virus infection of human monocytes and macrophages in vitroConformation of the dileucine-based sorting motif in HIV-1 Nef revealed by intermolecular domain assembly
P2860
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P2860
Genomic structure of an attenuated quasi species of HIV-1 from a blood transfusion donor and recipients
description
1995 nî lūn-bûn
@nan
1995 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
Genomic structure of an attenu ...... ansfusion donor and recipients
@ast
Genomic structure of an attenu ...... ansfusion donor and recipients
@en
Genomic structure of an attenu ...... ansfusion donor and recipients
@nl
type
label
Genomic structure of an attenu ...... ansfusion donor and recipients
@ast
Genomic structure of an attenu ...... ansfusion donor and recipients
@en
Genomic structure of an attenu ...... ansfusion donor and recipients
@nl
prefLabel
Genomic structure of an attenu ...... ansfusion donor and recipients
@ast
Genomic structure of an attenu ...... ansfusion donor and recipients
@en
Genomic structure of an attenu ...... ansfusion donor and recipients
@nl
P2093
P3181
P1433
P1476
Genomic structure of an attenu ...... ansfusion donor and recipients
@en
P2093
A Cunningham
A L Greenway
C Chatfield
D A McPhee
P304
P3181
P356
10.1126/SCIENCE.270.5238.988
P407
P577
1995-11-10T00:00:00Z