Synaptic vesicles position complexin to block spontaneous fusion - Wikidata - wikimedia - TriplyDB

Synaptic vesicles position complexin to block spontaneous fusion

Synaptic vesicles position complexin to block spontaneous fusion

http://www.wikidata.org/entity/Q28284213

about

Synaptotagmin-1 and -7 Are Redundantly Essential for Maintaining the Capacity of the Readily-Releasable Pool of Synaptic Vesicles Deconstructing complexin function in activating and clamping Ca2+-triggered exocytosis by comparing knockout and knockdown phenotypes Complexins: small but capable Synaptic vesicle recycling: steps and principles Evolutionary Divergence of the C-terminal Domain of Complexin Accounts for Functional Disparities between Vertebrate and Invertebrate Complexins Genetic analysis of the Complexin trans-clamping model for cross-linking SNARE complexes in vivo Membrane curvature sensing by the C-terminal domain of complexin.The accessory helix of complexin functions by stabilizing central helix secondary structure Synaptic activity regulates the abundance and binding of complexin.STARD4 Membrane Interactions and Sterol Binding.Evolutionary conservation of complexins: from choanoflagellates to mice.Phosphorylation of Complexin by PKA Regulates Activity-Dependent Spontaneous Neurotransmitter Release and Structural Synaptic Plasticity.Stabilization of spontaneous neurotransmitter release at ribbon synapses by ribbon-specific subtypes of complexin A time course of orchestrated endophilin action in sensing, bending, and stabilizing curved membranes.N-terminal domain of complexin independently activates calcium-triggered fusion.Molecular mechanisms of COMPLEXIN fusion clamp function in synaptic exocytosis revealed in a new Drosophila mutant Complexin-1 enhances the on-rate of vesicle docking via simultaneous SNARE and membrane interactions.C-terminal domain of mammalian complexin-1 localizes to highly curved membranes.Cognitive enhancing treatment with a PPARγ agonist normalizes dentate granule cell presynaptic function in Tg2576 APP mice.Complexin Mutants Reveal Partial Segregation between Recycling Pathways That Drive Evoked and Spontaneous Neurotransmission Complexin synchronizes primed vesicle exocytosis and regulates fusion pore dynamics.The blockade of the neurotransmitter release apparatus by botulinum neurotoxins.Unique Structural Features of Membrane-Bound C-Terminal Domain Motifs Modulate Complexin Inhibitory Function.Cortactin Is a Regulator of Activity-Dependent Synaptic Plasticity Controlled by Wingless.A C1-C2 Module in Munc13 Inhibits Calcium-Dependent Neurotransmitter Release.Complexin Binding to Membranes and Acceptor t-SNAREs Explains Its Clamping Effect on Fusion.Diverse modes of synaptic signaling, regulation, and plasticity distinguish two classes of C. elegans glutamatergic neurons.Hypothesis - buttressed rings assemble, clamp, and release SNAREpins for synaptic transmission.Hydrodynamics govern the pre-fusion docking time of synaptic vesicles.Cryo-EM structure and biochemical analysis reveal the basis of the functional difference between human PI3KC3-C1 and -C2.Nitric oxide-mediated posttranslational modifications control neurotransmitter release by modulating complexin farnesylation and enhancing its clamping ability.Solution NMR of SNAREs, complexin and α-synuclein in association with membrane-mimetics.Accessory and Central α-helices of Complexin Selectively Activate Ca2+ Triggering of Synaptic Exocytosis.A mechanism for exocytotic arrest by the Complexin C-terminus Mechanism of neurotransmitter release coming into focus Focused clamping of a single neuronal SNARE complex by complexin under high mechanical tension Local protein dynamics during microvesicle exocytosis in neuroendocrine cells

P2860

Q26269831-CD3A3CFE-C5EE-44DB-A965-1D6620483FA6 Q26269851-71AB5517-7B73-4AFE-B907-FF6FA0161F1C Q26798363-99BD0B4B-3B02-4A58-8759-F632E9278CFC Q26825177-555E548E-8EF8-4CC4-997D-E89AAAD439DF Q33729393-9F1C9D5A-23F8-4896-9F54-5C7AA7ABFD24 Q33925872-89C8D5C5-88C9-4C95-BABD-40F6D99EE6C5 Q34269080-8CC5E207-5C59-47C3-9951-910C163E6337 Q34729441-9B7061FE-2297-43A7-9640-A9AC513EC256 Q35221490-684EBF23-F426-44D6-8271-48C001FD8942 Q35923335-B44B5B1A-7E70-441B-9D8C-C9D8A988E812 Q36615769-65B3938A-0EFF-423F-B555-E4FEEB3EFB34 Q36844167-4AC20471-A73F-4609-A28B-9B5510B8C80B Q36959491-6D321812-8789-4123-9BCC-5BF5C9C0BF5E Q37052748-071E3ED9-6D30-44DA-84B0-9CF1759AFFB9 Q37181941-2A2C10B0-250A-497B-921F-71FCC2A379E6 Q37216827-ACFFD33A-AC1C-42B4-93DB-63B5CE8676B0 Q37370388-B5741C74-255D-4A1C-A058-7F6CB1629C07 Q37451152-9846993B-9F42-487E-9001-4CA91FF44BDC Q37479405-9D696C5B-0D90-4C3C-A76F-AAF5368B8674 Q37592135-18F07C7A-06F7-4F7D-A72A-091C41B27231 Q37677607-42FDE40D-CBB4-451A-B10F-07FEE525A940 Q38113138-1329D7CB-F928-4218-A3F8-CA2025A264AC Q42247505-425AE34B-F69B-4704-9EBB-B23438D3DBD4 Q42259062-20C439E8-0D40-47A3-BFE2-5A4EA4290BE2 Q42513230-5213FC6E-65FB-493A-A12D-245FF765FC90 Q45058072-E79C5487-3523-4E32-ABF3-5AF154BBCFF1 Q47104913-77D7007E-7F71-491D-AF9B-491BEF199E98 Q47139423-01BB0599-A4CF-44D5-8B05-447A9E3F5E73 Q48042734-29A13DD0-C1BA-4913-8D22-DF4D641AB041 Q50878334-E8E5310B-405B-4E15-BFC4-36075CCC3920 Q52598820-5050637E-9479-4EB5-9A4E-46CF89688377 Q52651765-9349FAE0-1701-4764-8E31-DBD91005D2C2 Q55324641-84243A23-E579-4E51-B6C7-9D88A0084958 Q56532061-26443F6D-9492-4D90-BC5F-C795C3819DE6 Q57173506-2B68956B-A8E9-4628-B6F1-18A3D14C2BD2 Q58759885-6A63AC24-D3AE-4863-A212-E35E724AF370 Q58806150-B66E0854-135C-423A-B705-112057530923

P2860

Synaptic vesicles position complexin to block spontaneous fusion

http://www.wikidata.org/entity/Q28284213

description

2013 nî lūn-bûn

@nan

2013 թուականի Յունուարին հրատարակուած գիտական յօդուած

@hyw

2013 թվականի հունվարին հրատարակված գիտական հոդված

@hy

2013年の論文

@ja

2013年論文

@yue

2013年論文

@zh-hant

2013年論文

@zh-hk

2013年論文

@zh-mo

2013年論文

@zh-tw

2013年论文

@wuu

name

Synaptic vesicles position complexin to block spontaneous fusion

@ast

Synaptic vesicles position complexin to block spontaneous fusion

@en

Synaptic vesicles position complexin to block spontaneous fusion

@nl

type

label

Synaptic vesicles position complexin to block spontaneous fusion

@ast

Synaptic vesicles position complexin to block spontaneous fusion

@en

Synaptic vesicles position complexin to block spontaneous fusion

@nl

prefLabel

Synaptic vesicles position complexin to block spontaneous fusion

@ast

Synaptic vesicles position complexin to block spontaneous fusion

@en

Synaptic vesicles position complexin to block spontaneous fusion

@nl

P1433

Q28284213-E25BF45A-A036-4C08-A776-8119B64DE06F

P1476

Q28284213-CDA1F136-27AA-4492-A5C4-8A3FEEDAC61C

P2093

Q28284213-0A4C70DC-E464-4CD3-B888-516CC336EFFA

Q28284213-0FE579D9-4F72-401F-AC65-8365DBFE4663

Q28284213-31DADBBE-34AC-4BD1-B2D3-7CE3FA8E0D67

Q28284213-6EBBCE9E-647B-4222-AFBD-A1CB91C8F11A

Q28284213-7A51B181-00AC-4A0C-9BEA-77F95D9E76A7

Q28284213-8BC6637C-C82D-4726-9552-295BCF854A72

Q28284213-C9C6B41A-B971-43D5-A1FC-3F55EB10469F

Q28284213-CBD68757-317A-4B2C-90AD-07DBAC4EB6DC

P2860

Q28284213-061123D1-948A-4665-8686-C26A7F44E4AC

Q28284213-06B95648-F916-425C-B5D8-E4E7437A9136

Q28284213-083A13D1-7036-4A88-B486-3F7EED460E96

Q28284213-0A9315ED-136C-4404-9ECE-E92F7E279800

Q28284213-0B6A622F-C067-40AD-8154-6B476E694BDC

Q28284213-128F2F2F-A587-43B4-B6F2-D1044E6E8FF0

Q28284213-1292A72A-1EDD-4D77-B33B-9DB56B8FF81E

Q28284213-15B3ED88-0E71-4B26-833D-0A1C4BAAA373

Q28284213-1B3F7A2A-6D9E-4C4A-AAD4-88F47A3D8F28

Q28284213-2A4D4F3D-C3EF-4EE6-96B3-4512C12C8400

P304

Q28284213-841F2C83-9BE6-4CF0-B633-31E2C459FFFB

P31

Q28284213-D83E3549-1347-406F-B7C9-2DF3D08F31F1

P3181

Q28284213-4016BE5F-065B-47D8-9424-D8170888F456

P356

Q28284213-6E7EADBD-A49A-4A8F-9BC2-61EB3740195C

P407

Q28284213-90A0E22B-DCDD-4E80-8034-FE9483932BA1

P433

Q28284213-0750A585-F15A-4BA5-85B5-06552B96AA22

P478

Q28284213-FE1419E7-9205-4C2F-B62D-C693FC3FE404

P577

Q28284213-172C36CE-025C-4EF6-A420-B90C14DD1471

P5875

Q28284213-ADC06C41-4F7F-42C9-BEEF-0D5064525306

P698

Q28284213-399F1803-25E1-4854-A5DD-DA71F988DCE8

P932

Q28284213-8229D9C3-A8A5-4103-A740-D8F819ADD01D

P3181

P356

J.NEURON.2012.11.005

P1433

P1476

Synaptic vesicles position complexin to block spontaneous fusion

@en

P2093

David Eliezer

http://www.w3.org/2001/XMLSchema#string

David Snead

http://www.w3.org/2001/XMLSchema#string

Indu Menon

http://www.w3.org/2001/XMLSchema#string

Jeremy S Dittman

http://www.w3.org/2001/XMLSchema#string

Jihong Bai

http://www.w3.org/2001/XMLSchema#string

Rachel T Wragg

http://www.w3.org/2001/XMLSchema#string

Trudy F Ramlall

http://www.w3.org/2001/XMLSchema#string

Yongming Dong

http://www.w3.org/2001/XMLSchema#string

P2860

C-terminal complexin sequence is selectively required for clamping and priming but not for Ca2+ triggering of synaptic exocytosis

Synaptic vesicle exocytosis

Complexin controls the force transfer from SNARE complexes to membranes in fusion

Molecular machines governing exocytosis of synaptic vesicles

Distinct initial SNARE configurations underlying the diversity of exocytosis

The Parallel Worm Tracker: a platform for measuring average speed and drug-induced paralysis in nematodes

Three-dimensional structure of the complexin/SNARE complex

X-ray structure of a neuronal complexin-SNARE complex from squid

Complexin cross-links prefusion SNAREs into a zigzag array

NMRPipe: a multidimensional spectral processing system based on UNIX pipes

P304

323-334

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P3181

1717571

http://www.w3.org/2001/XMLSchema#string

P356

10.1016/J.NEURON.2012.11.005

http://www.w3.org/2001/XMLSchema#string

P407

P433

2

http://www.w3.org/2001/XMLSchema#string

P478

77

http://www.w3.org/2001/XMLSchema#string

P577

2013-01-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

235374292

http://www.w3.org/2001/XMLSchema#string

P698

23352168

http://www.w3.org/2001/XMLSchema#string

P932

3559010

http://www.w3.org/2001/XMLSchema#string