16 alpha-substituted analogs of the antiprogestin RU486 induce a unique conformation in the human progesterone receptor resulting in mixed agonist activity

16 alpha-substituted analogs of the antiprogestin RU486 induce a unique conformation in the human progesterone receptor resulting in mixed agonist activity

Item
http://www.wikidata.org/entity/Q28285029
Jun dimerization protein 2 functions as a progesterone receptor N-terminal domain coactivator.X-ray Structures of Progesterone Receptor Ligand Binding Domain in Its Agonist State Reveal Differing Mechanisms for Mixed Profiles of 11 -Substituted SteroidsCoactivator/corepressor ratios modulate PR-mediated transcription by the selective receptor modulator RU486The nuclear corepressors NCoR and SMRT are key regulators of both ligand- and 8-bromo-cyclic AMP-dependent transcriptional activity of the human progesterone receptor.Role of nonhuman primate models in the discovery and clinical development of selective progesterone receptor modulators (SPRMs).Progesterone inhibits the growth of human neuroblastoma: in vitro and in vivo evidence.Progesterone antagonists and progesterone receptor modulators.Understanding how long-acting β2 -adrenoceptor agonists enhance the clinical efficacy of inhaled corticosteroids in asthma - an update.Enhancement of estrogen receptor transcriptional activity by the coactivator GRIP-1 highlights the role of activation function 2 in determining estrogen receptor pharmacology.An analysis of glucocorticoid receptor-mediated gene expression in BEAS-2B human airway epithelial cells identifies distinct, ligand-directed, transcription profiles with implications for asthma therapeutics.Steroid-induced conformational changes at ends of the hormone-binding domain in the rat glucocorticoid receptor are independent of agonist versus antagonist activity.
P2860

16 alpha-substituted analogs of the antiprogestin RU486 induce a unique conformation in the human progesterone receptor resulting in mixed agonist activity

Item
http://www.wikidata.org/entity/Q28285029
description
1996 nî lūn-bûn
@nan
1996 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
name
16 alpha-substituted analogs o ...... ting in mixed agonist activity
@ast
16 alpha-substituted analogs o ...... ting in mixed agonist activity
@en
16 alpha-substituted analogs o ...... ting in mixed agonist activity
@nl
type
label
16 alpha-substituted analogs o ...... ting in mixed agonist activity
@ast
16 alpha-substituted analogs o ...... ting in mixed agonist activity
@en
16 alpha-substituted analogs o ...... ting in mixed agonist activity
@nl
prefLabel
16 alpha-substituted analogs o ...... ting in mixed agonist activity
@ast
16 alpha-substituted analogs o ...... ting in mixed agonist activity
@en
16 alpha-substituted analogs o ...... ting in mixed agonist activity
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P5875
P698
P932
P356
P1433
P1476
16 alpha-substituted analogs o ...... ting in mixed agonist activity
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P5875
P698
P932