The CREB coactivator TORC2 functions as a calcium- and cAMP-sensitive coincidence detector
about
SIK2 is a centrosome kinase required for bipolar mitotic spindle formation that provides a potential target for therapy in ovarian cancerPhosphorylation of CRTC3 by the salt-inducible kinases controls the interconversion of classically activated and regulatory macrophagesCryptochrome mediates circadian regulation of cAMP signaling and hepatic gluconeogenesisCooperative interactions between CBP and TORC2 confer selectivity to CREB target gene expressionIndividual CREB-target genes dictate usage of distinct cAMP-responsive coactivation mechanismsDifferential 14-3-3 affinity capture reveals new downstream targets of phosphatidylinositol 3-kinase signalingTORC2, a coactivator of cAMP-response element-binding protein, promotes Epstein-Barr virus reactivation from latency through interaction with viral BZLF1 proteinTMEM203 Is a Novel Regulator of Intracellular Calcium Homeostasis and Is Required for SpermatogenesisTORC1 and TORC2 coactivators are required for tax activation of the human T-cell leukemia virus type 1 long terminal repeatsTranscriptional activation by MEIS1A in response to protein kinase A signaling requires the transducers of regulated CREB family of CREB co-activatorsSelective coupling of type 6 adenylyl cyclase with type 2 IP3 receptors mediates direct sensitization of IP3 receptors by cAMPTORC1 is a calcium- and cAMP-sensitive coincidence detector involved in hippocampal long-term synaptic plasticityTORC2 regulates germinal center repression of the TCL1 oncoprotein to promote B cell development and inhibit transformationTransducer of regulated CREB-binding proteins (TORCs) induce PGC-1alpha transcription and mitochondrial biogenesis in muscle cellsThe liver-enriched transcription factor CREB-H is a growth suppressor protein underexpressed in hepatocellular carcinomaRegulation of glucose metabolism from a liver-centric perspectiveSkin cancer in organ transplant recipients: effects of immunosuppressive medications on DNA repairTargeting sirtuin 1 to improve metabolism: all you need is NAD(+)?Calcineurin inhibition and new-onset diabetes mellitus after transplantationMolecular, cellular, and structural mechanisms of cocaine addiction: a key role for microRNAsLkb1 controls brown adipose tissue growth and thermogenesis by regulating the intracellular localization of CRTC3Eicosanoids in the innate immune response: TLR and non-TLR routesConverging roles of ion channels, calcium, metabolic stress, and activity pattern of Substantia nigra dopaminergic neurons in health and Parkinson's diseaseTransducer of regulated CREB and late phase long-term synaptic potentiationCREB--a real culprit in oncogenesisThe CRTC1-SIK1 pathway regulates entrainment of the circadian clockMolecular identification and characterization of a family of kinases with homology to Ca2+/calmodulin-dependent protein kinases I/IVCreb coactivators direct anabolic responses and enhance performance of skeletal muscleGlucagon regulates gluconeogenesis through KAT2B- and WDR5-mediated epigenetic effectsLeptin-mediated increases in catecholamine signaling reduce adipose tissue inflammation via activation of macrophage HDAC4Suppressor of MEK null (SMEK)/protein phosphatase 4 catalytic subunit (PP4C) is a key regulator of hepatic gluconeogenesisFeeding and Fasting Signals Converge on the LKB1-SIK3 Pathway to Regulate Lipid Metabolism in DrosophilaRequirement of TORC1 for late-phase long-term potentiation in the hippocampusActivity-dependent transport of the transcriptional coactivator CRTC1 from synapse to nucleusCREB coactivator CRTC2/TORC2 and its regulator calcineurin crucially mediate follicle-stimulating hormone and transforming growth factor β1 upregulation of steroidogenesisCellular mechanisms underlying the regulation of dendritic development by hepatocyte growth factorGlucose-dependent insulinotropic polypeptide-mediated up-regulation of beta-cell antiapoptotic Bcl-2 gene expression is coordinated by cyclic AMP (cAMP) response element binding protein (CREB) and cAMP-responsive CREB coactivator 2Melatonin influences insulin secretion primarily via MT(1) receptors in rat insulinoma cells (INS-1) and mouse pancreatic isletsCa1.2 and CaV1.3 neuronal L-type calcium channels: differential targeting and signaling to pCREBThe kinase LKB1 mediates glucose homeostasis in liver and therapeutic effects of metformin
P2860
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P2860
The CREB coactivator TORC2 functions as a calcium- and cAMP-sensitive coincidence detector
description
2004 nî lūn-bûn
@nan
2004 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
The CREB coactivator TORC2 fun ...... sensitive coincidence detector
@ast
The CREB coactivator TORC2 fun ...... sensitive coincidence detector
@en
The CREB coactivator TORC2 fun ...... sensitive coincidence detector
@nl
type
label
The CREB coactivator TORC2 fun ...... sensitive coincidence detector
@ast
The CREB coactivator TORC2 fun ...... sensitive coincidence detector
@en
The CREB coactivator TORC2 fun ...... sensitive coincidence detector
@nl
prefLabel
The CREB coactivator TORC2 fun ...... sensitive coincidence detector
@ast
The CREB coactivator TORC2 fun ...... sensitive coincidence detector
@en
The CREB coactivator TORC2 fun ...... sensitive coincidence detector
@nl
P2093
P3181
P1433
P1476
The CREB coactivator TORC2 fun ...... sensitive coincidence detector
@en
P2093
Gianluca Canettieri
Hiroshi Takemori
Jennifer L Best
John R Yates
Marc Montminy
Michael D Conkright
Mitsuhiro Okamoto
Shawn Jeffries
Sherry Niessen
Yoshiko Katoh
P3181
P356
10.1016/J.CELL.2004.09.015
P407
P577
2004-10-01T00:00:00Z