A single base mutation in the androgen receptor gene causes androgen insensitivity in the testicular feminized rat
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Testosterone activates mitogen-activated protein kinase and the cAMP response element binding protein transcription factor in Sertoli cellsThe role of androgen receptors in the masculinization of brain and behavior: what we've learned from the testicular feminization mutationDysregulation of neonatal hippocampal cell genesis in the androgen insensitive Tfm ratSex differences in social investigation: effects of androgen receptors, hormones and test partner.Of mice and rats: key species variations in the sexual differentiation of brain and behaviorA role for the androgen receptor in the sexual differentiation of the olfactory system in miceMale rats with the testicular feminization mutation of the androgen receptor display elevated anxiety-related behavior and corticosterone response to mild stress.The organizational role of testicular hormones and the androgen receptor in anxiety-related behaviors and sensorimotor gating in rats.Myocyte androgen receptors increase metabolic rate and improve body composition by reducing fat mass.Beta-catenin binds to the activation function 2 region of the androgen receptor and modulates the effects of the N-terminal domain and TIF2 on ligand-dependent transcriptionAndrogen receptor and Kennedy disease/spinal bulbar muscular atrophyMembrane androgen receptors may mediate androgen reinforcement.Research needs for the risk assessment of health and environmental effects of endocrine disruptors: a report of the U.S. EPA-sponsored workshop.Synthesis and biological evaluations of putative metabolically stable analogs of VN/124-1 (TOK-001): head to head anti-tumor efficacy evaluation of VN/124-1 (TOK-001) and abiraterone in LAPC-4 human prostate cancer xenograft model.Sex- and age-dependent effects of androgens on glutamate-induced cell death and intracellular calcium regulation in the developing hippocampusMutations in the ligand-binding domain of the androgen receptor gene cluster in two regions of the gene.Androgen receptors are required for full masculinization of the ventromedial hypothalamus (VMH) in rats.A frame-shift mutation in the androgen receptor gene causes complete androgen insensitivity in the testicular-feminized mouse.Systemic hypotensive effects of testosterone are androgen structure-specific and neuronal nitric oxide synthase-dependent.Regulation of Sertoli-germ cell adhesion and sperm release by FSH and nonclassical testosterone signaling.Effects of androgens and estradiol on spine synapse formation in the prefrontal cortex of normal and testicular feminization mutant male ratsTurning sex inside-out: Peripheral contributions to sexual differentiation of the central nervous system.Role of androgens and the androgen receptor in remodeling of spine synapses in limbic brain areasMouse Spermatogenesis Requires Classical and Nonclassical Testosterone Signaling.Sex differences and laterality in astrocyte number and complexity in the adult rat medial amygdala.Sexual differentiation of the nervous system: where the action is.Androgen regulates the sexually dimorphic gastrin-releasing peptide system in the lumbar spinal cord that mediates male sexual functionNeuroprotective actions of androgens on motoneurons.A role for the androgen metabolite, 5alpha-androstane-3beta,17beta-diol, in modulating oestrogen receptor beta-mediated regulation of hormonal stress reactivity.Profiling human androgen receptor mutations reveals treatment effects in a mouse model of prostate cancerZinc fingers, zinc clusters, and zinc twists in DNA-binding protein domains.The Gastrin-Releasing Peptide Receptor (GRPR) in the Spinal Cord as a Novel Pharmacological TargetA distal activation domain is critical in the regulation of the rat androgen receptor gene promoterSystematic structure modifications of multitarget prostate cancer drug candidate galeterone to produce novel androgen receptor down-regulating agents as an approach to treatment of advanced prostate cancer.Evidence that the androgen receptor mediates sexual differentiation of mouse renal cytochrome P450 expression.
P2860
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P2860
A single base mutation in the androgen receptor gene causes androgen insensitivity in the testicular feminized rat
description
1990 nî lūn-bûn
@nan
1990 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1990 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1990年の論文
@ja
1990年論文
@yue
1990年論文
@zh-hant
1990年論文
@zh-hk
1990年論文
@zh-mo
1990年論文
@zh-tw
1990年论文
@wuu
name
A single base mutation in the ...... n the testicular feminized rat
@ast
A single base mutation in the ...... n the testicular feminized rat
@en
A single base mutation in the ...... n the testicular feminized rat
@nl
type
label
A single base mutation in the ...... n the testicular feminized rat
@ast
A single base mutation in the ...... n the testicular feminized rat
@en
A single base mutation in the ...... n the testicular feminized rat
@nl
prefLabel
A single base mutation in the ...... n the testicular feminized rat
@ast
A single base mutation in the ...... n the testicular feminized rat
@en
A single base mutation in the ...... n the testicular feminized rat
@nl
P2093
P1476
A single base mutation in the ...... n the testicular feminized rat
@en
P2093
D B Lubahn
D R Joseph
E M Wilson
F S French
J A Simental
V E Quarmby
W G Yarbrough
P304
P407
P577
1990-05-25T00:00:00Z