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Quantitative visualization of DNA G-quadruplex structures in human cells

Quantitative visualization of DNA G-quadruplex structures in human cells

http://www.wikidata.org/entity/Q28285848

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Electrochemical sensors and biosensors based on nanomaterials and nanostructures Zika Virus Genomic RNA Possesses Conserved G-Quadruplexes Characteristic of the Flaviviridae Family Getting Ready for the Dance: FANCJ Irons Out DNA Wrinkles Structure and function of the telomeric CST complex G-quadruplexes and helicases G-quadruplexes and their regulatory roles in biology Replication of Structured DNA and its implication in epigenetic stability Activated Ras as a Therapeutic Target: Constraints on Directly Targeting Ras Isoforms and Wild-Type versus Mutated Proteins G-quadruplex formation in double strand DNA probed by NMM and CV fluorescence.Solution structure of the major G-quadruplex formed in the human VEGF promoter in K+: insights into loop interactions of the parallel G-quadruplexes Structural Studies on Dinuclear Ruthenium(II) Complexes That Bind Diastereoselectively to an Antiparallel Folded Human Telomere Sequence A G-quadruplex–containing RNA activates fluorescence in a GFP-like fluorophore Structural basis of DNA quadruplex-duplex junction formation Photoresponsive Formation of an Intermolecular Minimal G-Quadruplex Motif Solution and Solid-State Analysis of Binding of 13-Substituted Berberine Analogues to Human Telomeric G-quadruplexes Structure and possible function of a G-quadruplex in the long terminal repeat of the proviral HIV-1 genome NMR Structure of a Triangulenium-Based Long-Lived Fluorescence Probe Bound to a G-Quadruplex Effects of DNA supercoiling on chromatin architecture Do we know whether potential G-quadruplexes actually form in long functional RNA molecules?G-quadruplexes in pathogens: a common route to virulence control?G-quadruplexes: Emerging roles in neurodegenerative diseases and the non-coding transcriptome RNA Exosome Regulates AID DNA Mutator Activity in the B Cell Genome Mammalian DNA2 helicase/nuclease cleaves G-quadruplex DNA and is required for telomere integrity The G4 genome Targeting human telomeric G-quadruplex DNA and inhibition of telomerase activity with [(dmb)2Ru(obip)Ru(dmb)2](4+)Pyrrolobenzodiazepines (PBDs) do not bind to DNA G-quadruplexes BLM helicase facilitates telomere replication during leading strand synthesis of telomeres Single-molecule imaging reveals a common mechanism shared by G-quadruplex-resolving helicases A core extended naphtalene diimide G-quadruplex ligand potently inhibits herpes simplex virus 1 replication Conserved presence of G-quadruplex forming sequences in the Long Terminal Repeat Promoter of Lentiviruses A Nitroxide-Tagged Platinum(II) Complex Enables the Identification of a DNA G-Quadruplex Binding Mode Cobalt(III)porphyrin to target G-quadruplex DNA.Exploring possible DNA structures in real-time polymerase kinetics using Pacific Biosciences sequencer data G-quadruplexes with (4n - 1) guanines in the G-tetrad core: formation of a G-triad·water complex and implication for small-molecule binding Selective Luminescent Labeling of DNA and RNA Quadruplexes by π-Extended Ruthenium Light-Up Probes.G quadruplexes are genomewide targets of transcriptional helicases XPB and XPD.Specific targeting of telomeric multimeric G-quadruplexes by a new triaryl-substituted imidazole.Reversible manipulation of the G-quadruplex structures and enzymatic reactions through supramolecular host-guest interactions QGRS-Conserve: a computational method for discovering evolutionarily conserved G-quadruplex motifs.Proteomic Profiling Reveals a Specific Role for Translesion DNA Polymerase η in the Alternative Lengthening of Telomeres.

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Quantitative visualization of DNA G-quadruplex structures in human cells

http://www.wikidata.org/entity/Q28285848

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2013 nî lūn-bûn

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2013 թուականի Մարտին հրատարակուած գիտական յօդուած

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2013 թվականի մարտին հրատարակված գիտական հոդված

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2013年の論文

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Quantitative visualization of DNA G-quadruplex structures in human cells

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Quantitative visualization of DNA G-quadruplex structures in human cells

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Quantitative visualization of DNA G-quadruplex structures in human cells

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type

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Quantitative visualization of DNA G-quadruplex structures in human cells

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Quantitative visualization of DNA G-quadruplex structures in human cells

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Quantitative visualization of DNA G-quadruplex structures in human cells

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Quantitative visualization of DNA G-quadruplex structures in human cells

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Quantitative visualization of DNA G-quadruplex structures in human cells

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Quantitative visualization of DNA G-quadruplex structures in human cells

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Nature Chemistry

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Quantitative visualization of DNA G-quadruplex structures in human cells

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P2093

John McCafferty

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Shankar Balasubramanian

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P2860

Highly prevalent putative quadruplex sequence motifs in human DNA

Prevalence of quadruplexes in the human genome.

Direct evidence for a G-quadruplex in a promoter region and its targeting with a small molecule to repress c-MYC transcription

In vitro generated antibodies specific for telomeric guanine-quadruplex DNA react with Stylonychia lemnae macronuclei

Telomere end-binding proteins control the formation of G-quadruplex DNA structures in vivo

Formation of parallel four-stranded complexes by guanine-rich motifs in DNA and its implications for meiosis

Telomestatin-induced telomere uncapping is modulated by POT1 through G-overhang extension in HT1080 human tumor cells.

Application of phage display to high throughput antibody generation and characterization.

A novel small molecule that alters shelterin integrity and triggers a DNA-damage response at telomeres.

A single-molecule platform for investigation of interactions between G-quadruplexes and small-molecule ligands.

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182-186

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scholarly article

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613953

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10.1038/NCHEM.1548

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3

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5

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David Tannahill

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2013-01-20T00:00:00Z

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235669010

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1006538099

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23422559

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3622242

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