Loss of SHIP and CIS recruitment to the granulocyte colony-stimulating factor receptor contribute to hyperproliferative responses in severe congenital neutropenia/acute myelogenous leukemia
about
The role of suppressors of cytokine signalling in human neoplasmsG-CSFR ubiquitination critically regulates myeloid cell survival and proliferation.Granulocyte colony-stimulating factor: molecular mechanisms of action during steady state and 'emergency' hematopoiesis.Recent advances in the bcr-abl negative chronic myeloproliferative diseases.Src family kinases are important negative regulators of G-CSF-dependent granulopoiesisHematopoietic growth factors, signaling and the chronic myeloproliferative disorders.Role of the proteasome in modulating native G-CSFR expression.Establishment of cancer cell lines from rat hepatocholangiocarcinoma and assessment of the role of granulocyte-colony stimulating factor and hepatocyte growth factor in their growth, motility and survival.Inhibitor and activator: dual functions for SHIP in immunity and cancer.SOCS proteins in development and disease.Granulocyte colony-stimulating factor receptor mutations in myeloid malignancy.Granulocyte colony-stimulating factor receptor signaling in severe congenital neutropenia, chronic neutrophilic leukemia, and related malignancies.Alternatively spliced, truncated GCSF receptor promotes leukemogenic properties and sensitivity to JAK inhibition.Multiple pathways contribute to the hyperproliferative responses from truncated granulocyte colony-stimulating factor receptors.Tyrosine 729 of the G-CSF receptor controls the duration of receptor signaling: involvement of SOCS3 and SOCS1.Enhanced MAPK signaling is essential for CSF3R-induced leukemia.
P2860
Q27026783-E01519EE-4AB9-4030-826C-AB38DC8A1DDAQ33377020-9C6B50F8-D2A5-4B4B-A5CB-EBB934BF58FDQ33780538-34A555AD-3790-40FA-B8A8-6E61FC4AF1C1Q35126938-18EF6BCB-8427-434E-A91E-5E0A5CCB9156Q35849188-40F11E60-1750-4177-AE0A-071F5BB45DB2Q36630747-3A3CFCF4-6A23-4DCA-A606-355E91CC1920Q36915628-C7F322C5-1C13-4923-921F-68BD3FF3C61DQ37222193-D3E9A453-9976-4741-A4F6-5D93F6024073Q37820689-F8955EB8-ECA2-4958-A32F-7F188F512558Q38124037-DEEC4A53-995B-45DF-85F0-A35F22FD0591Q38211431-8DEF9801-BBF4-4063-A780-2502A49B3779Q38993081-99B694FF-E34F-45CA-8A2C-DA40A932A075Q39068979-557784E6-9688-46F4-968B-FC342361B96AQ40215423-49EAEEDB-AAC8-482E-9FE8-7B501C5CF925Q40395394-84AEA5A4-8119-45C8-BA81-CD17E613EF04Q41190362-6032B80A-5C42-44B2-B62E-176ACA20F5CA
P2860
Loss of SHIP and CIS recruitment to the granulocyte colony-stimulating factor receptor contribute to hyperproliferative responses in severe congenital neutropenia/acute myelogenous leukemia
description
2004 nî lūn-bûn
@nan
2004 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Loss of SHIP and CIS recruitme ...... nia/acute myelogenous leukemia
@ast
Loss of SHIP and CIS recruitme ...... nia/acute myelogenous leukemia
@en
Loss of SHIP and CIS recruitme ...... nia/acute myelogenous leukemia
@nl
type
label
Loss of SHIP and CIS recruitme ...... nia/acute myelogenous leukemia
@ast
Loss of SHIP and CIS recruitme ...... nia/acute myelogenous leukemia
@en
Loss of SHIP and CIS recruitme ...... nia/acute myelogenous leukemia
@nl
prefLabel
Loss of SHIP and CIS recruitme ...... nia/acute myelogenous leukemia
@ast
Loss of SHIP and CIS recruitme ...... nia/acute myelogenous leukemia
@en
Loss of SHIP and CIS recruitme ...... nia/acute myelogenous leukemia
@nl
P2093
P1476
Loss of SHIP and CIS recruitme ...... nia/acute myelogenous leukemia
@en
P2093
Amanda Agler
Anand Jacob
Belinda R Avalos
K Mark Coggeshall
Lawrence J Druhan
Lynn C O'donnell
Melissa G Hunter
P304
P356
10.4049/JIMMUNOL.173.8.5036
P407
P577
2004-10-15T00:00:00Z