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HMB supplementation: clinical and athletic performance-related effects and mechanisms of action

HMB supplementation: clinical and athletic performance-related effects and mechanisms of action

http://www.wikidata.org/entity/Q28287244

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Leucine is a major regulator of muscle protein synthesis in neonates International Society of Sports Nutrition Position Stand: beta-hydroxy-beta-methylbutyrate (HMB)Beta-hydroxy-beta-methylbutyrate supplementation in health and disease: a systematic review of randomized trials Novel insights on nutrient management of sarcopenia in elderly β-Hydroxy β-methylbutyrate improves dexamethasone-induced muscle atrophy by modulating the muscle degradation pathway in SD rat Leucine and HMB differentially modulate proteasome system in skeletal muscle under different sarcopenic conditions The effects of 12 weeks of beta-hydroxy-beta-methylbutyrate free acid supplementation on muscle mass, strength, and power in resistance-trained individuals: a randomized, double-blind, placebo-controlled study.A metabolite of leucine (β-hydroxy-β-methylbutyrate) given to sows during pregnancy alters bone development of their newborn offspring by hormonal modulation.The role of leucine and its metabolites in protein and energy metabolism.Enteral β-hydroxy-β-methylbutyrate supplementation increases protein synthesis in skeletal muscle of neonatal pigs.Leucine Metabolism in T Cell Activation: mTOR Signaling and Beyond.β-Hydroxy-β-methylbutyrate (HMβ) supplementation stimulates skeletal muscle hypertrophy in rats via the mTOR pathway Immune Function and Muscle Adaptations to Resistance exercise in Older Adults: Study Protocol for a Randomized Controlled Trial of a Nutritional Supplement.Effects of dairy consumption on SIRT1 and mitochondrial biogenesis in adipocytes and muscle cells.The efficacy of a β-hydroxy-β-methylbutyrate supplementation on physical capacity, body composition and biochemical markers in elite rowers: a randomised, double-blind, placebo-controlled crossover study Protein synthesis in skeletal muscle of neonatal pigs is enhanced by administration of β-hydroxy-β-methylbutyrate.Simultaneous quantification of salivary 3-hydroxybutyrate, 3-hydroxyisobutyrate, 3-hydroxy-3-methylbutyrate, and 2-hydroxybutyrate as possible markers of amino acid and fatty acid catabolic pathways by LC-ESI-MS/MS.β-hydroxy-β-methylbutyrate did not enhance high intensity resistance training-induced improvements in myofiber dimensions and myogenic capacity in aged female rats The role of dietary protein intake in the prevention of sarcopenia of aging.High-intensity interval training and β-hydroxy-β-methylbutyric free acid improves aerobic power and metabolic thresholds.β-Hydroxy-β-methylbutyrate, mitochondrial biogenesis, and skeletal muscle health.Conversion of leucine to β-hydroxy-β-methylbutyrate by α-keto isocaproate dioxygenase is required for a potent stimulation of protein synthesis in L6 rat myotubes Effects of Dietary Supplementation of β-hydroxy-β-methylbutyrate on Sow Performance and mRNA Expression of Myogenic Markers in Skeletal Muscle of Neonatal Piglets.Effects of β-Hydroxy-β-methylbutyrate Free Acid Ingestion and Resistance Exercise on the Acute Endocrine Response.The Effect of a 12-Week Beta-hydroxy-beta-methylbutyrate (HMB) Supplementation on Highly-Trained Combat Sports Athletes: A Randomised, Double-Blind, Placebo-Controlled Crossover Study.Current knowledge about sports nutrition.Production of 2-ketoisocaproate with Corynebacterium glutamicum strains devoid of plasmids and heterologous genes.Metabolic engineering of Corynebacterium glutamicum for 2-ketoisocaproate production.Glucose intolerance induced by glucocorticoid excess is further impaired by co-administration with β-hydroxy-β-methylbutyrate in rats.Effects of β-hydroxy-β-methyl butyrate on working memory and cognitive flexibility in an animal model of aging.Effects of beta-hydroxy-beta-methylbutyrate (HMB) on the expression of ubiquitin ligases, protein synthesis pathways and contractile function in extensor digitorum longus (EDL) of fed and fasting rats.Metabolic and functional effects of beta-hydroxy-beta-methylbutyrate (HMB) supplementation in skeletal muscle.Effect of β-hydroxy-β-methylbutyrate in masticatory muscles of rats.The addition of beta-hydroxy-beta-methylbutyrate and isomaltulose to whey protein improves recovery from highly demanding resistance exercise.Effects of Alpha-hydroxy-isocaproic acid upon Body Composition in a Type I Diabetic Patient with Muscle Atrophy – A Case Study.

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HMB supplementation: clinical and athletic performance-related effects and mechanisms of action

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2011 nî lūn-bûn

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2011年の論文

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Antonio Herbert Lancha

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Fabio Santos Lira

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Lucas Guimarães-Ferreira

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Mário Alves de Siqueira Filho

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Vitor Felitti

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P2860

Effects of beta-hydroxy-beta-methylbutyrate (HMB) on exercise performance and body composition across varying levels of age, sex, and training experience: A review

Viral mediated expression of insulin-like growth factor I blocks the aging-related loss of skeletal muscle function

Akt/mTOR pathway is a crucial regulator of skeletal muscle hypertrophy and can prevent muscle atrophy in vivo

Beta-hydroxy-beta-methylbutyrate (HMB) stimulates myogenic cell proliferation, differentiation and survival via the MAPK/ERK and PI3K/Akt pathways

Protein degradation by the ubiquitin-proteasome pathway in normal and disease states

Beta-hydroxy-beta-methylbutyrate ingestion, Part I: effects on strength and fat free mass.

Creatine and beta-hydroxy-beta-methylbutyrate (HMB) additively increase lean body mass and muscle strength during a weight-training program.

Reversal of cancer-related wasting using oral supplementation with a combination of beta-hydroxy-beta-methylbutyrate, arginine, and glutamine.

Attenuation of proteasome-induced proteolysis in skeletal muscle by {beta}-hydroxy-{beta}-methylbutyrate in cancer-induced muscle loss.

Signaling pathways initiated by beta-hydroxy-beta-methylbutyrate to attenuate the depression of protein synthesis in skeletal muscle in response to cachectic stimuli.

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Marília Seelaender

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